Biochemistry and Cell Biology

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New roles for PagP in bacterial evasion of host immune defenses 2014
A cell-based high-throughput screening system to identify inhibitors of the VirB8 type IV secretion system component from Brucella suis 2008
A chemical biology approach to probing aminoglycoside phosphotransferase structure and function 2008
A chemical genetic matrix for rational discovery of novel small molecule synergies 2008
A multicomponent platform for elucidating targets of antifungal compounds 2008
Characterization of the putative cell wall stress signaling protein YwaCs and its applications in small molecule screening 2008
Dimerization of VirB8 is essential for type IV secretion system function 2008
Engineering amino acid responsive riboswitch biosensors 2008
Glycogen synthase kinase 3 beta inhibition assay using a sol-gel derived multi-component microarray 2008
Identification and in vitro characterization of novel adenosine kinase (AK) inhibitors 2008
Identification of an antibacterial small molecule with novel mode of action using forward chemical genetics 2008
Insights into the catalytic mechanism of phosphoheptose isomerase (GmhA), a drug target for combating gram-negative bacterial infection 2008
Interaction of the Escherichia coli GTPase EngA with the ribosome 2008
Investigating the requirement for teichoic acid polymers in gram-positive bacteria 2008
Novel effects of the cysteine alkylators N-ethylmaleimide and ethacrynic acid on mitochondrial fusion and fission dynamics 2008
Profiling of the transcriptional response of Escherichia coli yjeE to antibiotics suggests a role for this unknown ATPase in stress response 2008
Small and lethal: searching for new antibacterial compounds with novel modes of action 2008
Solid-phase assays for small molecule screening using sol-gel entrapped proteins 2008
The Canadian chemical biology network: a national resource for Canadian academics 2008
The coupling of an immobilized enzyme reactor with bioextraction - tandem mass spectrometry for identification of enzyme inhibitors in mixtures 2008
Using flow cytometry to select for artificial riboswitches 2008
An intrinsic exciton probe reports methylene unit resolution in the PagP hydrocarbon ruler 2006
Characterizing Bax-tBid function at the mitochondrial membrane isolated from bak(-/-) mice 2006
Hypothesis: huntingtin may function in membrane association and vesicular traffickingThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB — Membrane Proteins in Health and Disease. 2006
Structure-function studies of Pseudomonas aeruginosa type IV pilus cell-wall scaffold proteins 2006
Skeletal Muscle Mitochondrial Morphology Negatively Affected in Mice Lacking Xin. 102:373-384. 2024
Post-transcriptional regulation in hematopoiesis: RNA binding proteins take control. 97:10-20. 2019
Optimizing dimodular nonribosomal peptide synthetases and natural dipeptides in an Escherichia coli heterologous host. 91:203-208. 2013
The impact of the ovarian microenvironment on the anti-tumor effect of SPARC on ovarian cancer¹This article is part of Special Issue entitled Asilomar Chromatin and has undergone the Journal’s usual peer review process.. 90:96-107. 2012
CYB5D2 enhances HeLa cells survival of etoposide-induced cytotoxicity. 89:341-350. 2011
Effect of FKBP65, a putative elastin chaperone, on the coacervation of tropoelastin in vitro. 88:917-925. 2010
Chemical biology of tetracycline antibioticsThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB — Systems and Chemical Biology, and has undergone the Journal's usual peer review process.. 86:124-136. 2008
Comment: Canadian Chemical Biology Network: biochemistry back to the future / Commentaire : Réseau canadien de biologie chimique: la biochimie de retour vers le futur. 86:ix-xii. 2008
Introduction: Chemical Biology meets Systems Biology / Introduction : Convergence de la biologie chimique et de la biologie systémique. 86:vii-viii. 2008
Small and lethal: searching for new antibacterial compounds with novel modes of actionThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB — Systems and Chemical Biology, and has undergone the Journal's usual peer review process.. 86:111-115. 2008
Solid-phase assays for small molecule screening using sol-gel entrapped proteinsThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB — Systems and Chemical Biology, and has undergone the Journal's usual peer review process.. 86:100-110. 2008
Control of mitochondrial gene expression in the aging rat myocardium. 84:191-198. 2006
The structural basis for the serospecificity ofActinobacillus suisserogroup O:2. 84:184-190. 2006
Conserved P-loop GTPases of unknown function in bacteria: an emerging and vital ensemble in bacterial physiology. 83:738-746. 2005
Solid-state ²H NMR study of methyl-d₃-cobalamin. 76:423-428. 1998
Heat-induced thermal tolerance and radiation resistance to apoptosis in human lymphocytes. 75:393-397. 1997
Neuronal Cdc2-like kinase: from cell cycle to neuronal function. 74:419-429. 1996
Membrane permeation and intracellular trafficking of long chain fatty acids: insights fromEscherichia coliand 3T3-L1 adipocytes. 73:223-234. 1995
Modification of radiation-induced apoptosis in radiation- or hyperthermia-adapted human lymphocytes. 72:475-482. 1994
Role of proteolysis in apoptosis: involvement of serine proteases in internucleosomal DNA fragmentation in immature thymocytes. 71:488-500. 1993
Reconstitution of rabbit sarcoplasmic reticulum calcium ATPase in a series of phosphatidylcholines containing a saturated and an unsaturated chain: suggestion of an optimal lipid environment. 71:381-389. 1993
Synthesis and characterization of a fragment of an ice nucleation protein. 71:236-240. 1993
Fatty acid uptake in Escherichia coli: regulation by recruitment of fatty acyl-CoA synthetase to the plasma membrane. 71:51-56. 1993
Interrelationships of endoplasmic reticulum, mitochondria, intermediate filaments, and microtubules—a quadruple fluorescence labeling study. 70:1174-1186. 1992
Quantitative analysis of regions of adenovirus E1A products involved in interactions with cellular proteins. 70:1123-1134. 1992
Regulation of gene expression in oncogenically transformed cells. 70:980-997. 1992
Transport of Ca²⁺ by diltiazem across the lipid bilayer in model liposomes. 70:608-612. 1992
Multifactorial resistance to antineoplastic agents in drug-resistant P388 murine leukemia, Chinese hamster ovary, and human HeLa cells, with emphasis on the role of DNA topoisomerase II. 70:354-364. 1992
Fatty acid uptake in Candida tropicalis: induction of a saturable process. 70:76-80. 1992
Peptide hormones, neurotransmitters, and drugs as Ca²⁺ ionophores: implications for signal transduction. 69:93-95. 1991
Microtubules, mitochondria, and molecular chaperones: a new hypothesis for in vivo assembly of microtubules. 68:1352-1363. 1990
Cross-resistance and biochemical characteristics of second-step mutants of HeLa cells resistant to cardiac glycosides. 68:852-857. 1990
Synthesis of acyl-CoA thioesters. 68:308-312. 1990
A comparison of two procedures used for complexing Fe(III) with human apotransferrin. II. Uptake of Fe(III) by K-562 cells from ⁵⁵Fe∙transferrins and Fe∙[³H]transferrins. 65:271-279. 1987
A comparison of two procedures used for complexing Fe(III) with human apotransferrin: I. physicochemical properties of the Fe(III) transferrin products. 64:936-945. 1986
Aggregation of smooth muscle membranes and its use in the preparation of plasma membrane enriched fraction from gastric fundus smooth muscle. 64:535-542. 1986
Chinese hamster ovary cell mutants specifically affected in the phosphorylation of C-purine nucleosides. 63:1044-1048. 1985
Protein kinase and ATP-binding activity associated with the 72-kdalton single-stranded DNA-binding protein from early region 2A of human adenovirus type 5. 63:941-952. 1985
On the interaction between 5-hydroxytryptamine and N-acetylneuraminic acid under aqueous conditions. 63:757-763. 1985
Genetic and biochemical studies with mutants of mammalian cells affected in microtubule-related proteins other than tubulin: mitochondrial localization of a microtubule-related protein. 63:489-502. 1985
Release of ferrous iron from ferritin by liver microsomes: a possible role in the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin. 62:1293-1300. 1984
Association of the nucleocapsid protein N of vesicular stomatitis virus with phospholipids vesicles containing the matrix protein M. 62:1174-1180. 1984
Effects of heparin fractions of different affinities to antithrombin III and thrombin on the inactivation of thrombin and factor Xa by antithrombin III. 62:975-983. 1984
Biosynthetic utilization of photoreactive fatty acids by rat liver microsomes. 62:375-378. 1984
Some properties of aminopeptidase associated with rat brain cortical synaptosomes. 61:1185-1190. 1983
Antibodies to indolealkylamines II: site of conjugation of melatonin to protein using formaldehyde. 61:1096-1101. 1983
Interaction of D-phenylalanine with Co(II)-substituted rabbit muscle pyruvate kinase: kinetic and optical properties. 60:861-866. 1982
The structural heterogeneity of the carbohydrate moiety of desiaiylated human transferrin. 60:624-630. 1982
Vitellogenin mRNA in locust fat body: identification, isolation, and quantitative changes induced by juvenile hormone. 60:243-251. 1982
Hybrid aspartate transcarbamoylase containing cross-linked subunits. 59:461-468. 1981
Conformation of cross-linked aspartate transcarbamoylase. 59:371-378. 1981
L-Phenylalanine induced changes of sulfhydryl reactivity in rabbit muscle pyruvate kinase. 59:92-99. 1981
Multivalent interaction between asialofetuin and plasma membrane preparations from the rat liver. 58:1414-1420. 1980
Antifreeze proteins from the shorthorn sculpin, Myoxocephalus scorpius: isolation and characterization.. 58:377-383. 1980
13C and 31P nuclear magnetic resonance of lipid dispersions from human aorta.. 58:206-207. 1980
Chromatography of heparin on Sepharose–lysine: molecular size fractionation and its relevance to thrombin and antithrombin III binding. 57:1183-1190. 1979
The effect of membrane cholesterol depletion upon erythrocyte membrane-bound enzymes. 57:1144-1152. 1979
Aspartate transcarbamoylase: loss of homotropic but not heterotropic interactions upon modification of the catalytic subunit with a bifunctional reagent. 57:798-805. 1979
Structure and function of aspartate transcarbamoylase studied using chymotrypsin as a probe. 56:654-658. 1978
Bovine transferrin glycopeptide: the relevance of its structure to interaction with the mammalian hepatic lectin that binds asialoglycoproteins. 56:339-344. 1978
Incorporation in vivo of [³²P]orthophosphate and [Me-³H]choline into rough microsomal, Golgi, and plasma membranes of rat liver. 55:876-885. 1977
Purification and properties of dihydrofolate reductase from methotrexate-sensitive and methotrexate-resistant Chinese hamster ovary cells. 55:445-452. 1977
Evidence from rotatory measurements for an intermediate state in the guanidine hydrochloride denaturation of β-lactoglobulin. 55:239-243. 1977
Further studies on aspartate transcarbamoylase: molecular weight of the c₃r₆ complex and analysis of succinate inhibition in the native enzyme. 54:1061-1068. 1976
Some experimental approaches for studying subunit interactions in enzymes. 54:521-528. 1976
Studies of the metabolism of asialotransferrins: nonspecific changes in the metabolic behaviour of human asialotransferrin in avians. 54:336-340. 1976
Studies of the Metabolism of Asialotransferrins: the in Vivo Behavior of Baboon and Rhesus Asialotransferrins. 53:1255-1261. 1975
Studies of the Metabolism of Asialotransferrins: the Metabolic Heterogeneity of Human Asialotransferrin. 53:1070-1077. 1975
Studies of the Metabolism of Asialotransferrins: Relationship Between the Carbohydrate Composition of Bovine, Canine, and Porcine Asialotransferrins and their Metabolic Behavior in the Rabbit. 52:845-853. 1974
Studies of the Metabolism of Asialotransferrins: The Mechanism for the Hypercatabolism of Human Asialotransferrin in the Rabbit. 52:645-651. 1974
Antibodies to Indolealkylamines; Serotonin and Melatonin. 52:196-202. 1974
Studies of the Metabolism of Asialotransferrins: Potentiation of the Catabolism of Human Asialotransferrin in the Rabbit. 52:155-161. 1974
Biosynthesis of Vitamin B₆. Incorporation of Terminally Labelled Glucose. 51:1412-1416. 1973
Studies on Protein Subunits. V. Specific Interaction between Matrix–Bound Subunits of Aldolase and Soluble Aldolase Subunits. 51:1240-1247. 1973
Chromatography of Drosophila tRNA on BD-cellolose. 51:896-902. 1973
The Electron Paramagnetic Resonance Spectrum of Ferricytochrome c and Lysine-Modified Derivatives at Alkaline pH. 51:465-471. 1973
The pH-Induced Transition of Iodinated Ferricytochrome c: Electron Paramagnetic Resonance and Absorption Spectra. 51:472-475. 1973
Further Codon Assignments in an Extremely Halophilic Bacterium using a Cell-Free Protein-Synthesizing System and a Ribosomal Binding Assay. 50:600-609. 1972
Hemoglobin Binding by Enzymatic Fragments of Haptoglobin. 49:637-640. 1971
The Electron Paramagnetic Resonance Spectrum at 77 °K of Lyophilized and Frozen Solutions of Horse Heart Ferricytochrome c. 49:328-331. 1971
Fragmentation of Haptoglobin by Plasmin. 49:90-96. 1971
Reaction of N-methyl-N'-nitro-N-nitrosoguanidine with protein: formation of nitroguanido derivatives.. 46:1410-1415. 1968
Inactivation of biologically active N-methyl-N-nitroso compounds in aqueous solution: effect of various conditions of pH and illumination.. 46:807-811. 1968
A simple method for the isolation of fraction I protein of chloroplasts.. 46:441-444. 1968
Inhibition of Euglena macromolecule synthesis by N-methyl-N-nitro-N-nitrosoguanidine and N-methyl-N-nitroso-p-toluenesulfonamide.. 45:1357-1363. 1967
EFFECTS OF SOME NITROFURANS ON DNA SYNTHESIS AND PROPHAGE INDUCTION.. 42:1245-1247. 1964

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