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Modification of radiation-induced apoptosis in...
Journal article

Modification of radiation-induced apoptosis in radiation- or hyperthermia-adapted human lymphocytes

Abstract

We have investigated the influence of the cellular adaptive response to ionizing radiation on radiation-induced apoptosis in human cells. The adaptive response is believed to be a protective mechanism that confers resistance to the detrimental effects of ionizing radiation and that can be induced by different agents, including hyperthermia and radiation. We have used fluorescence analysis of DNA unwinding (FADU) to assay the induction of …

Authors

Cregan SP; Boreham DR; Walker PR; Brown DL; Mitchel RE

Journal

Biochemistry and Cell Biology, Vol. 72, No. 11-12, pp. 475–482

Publisher

Canadian Science Publishing

Publication Date

November 1, 1994

DOI

10.1139/o94-064

ISSN

0829-8211