Journal article
Some properties of aminopeptidase associated with rat brain cortical synaptosomes
Abstract
To understand the breakdown of peptides in the brain, we studied the aminopeptidase associated with synaptosome particles. A continuous spectrophotometric assay in stirred cuvettes was used to follow the kinetics of inactivation by EDTA and by diethyl pyrocarbonate. The sensitivity of the enzyme towards puromycin and leucine hydroxamate was also determined. The results are consistent with the presence of a single species of aminopeptidase in …
Authors
Chan WW-C; Demmer W; Brand K
Journal
Biochemistry and Cell Biology, Vol. 61, No. 11, pp. 1185–1190
Publisher
Canadian Science Publishing
Publication Date
November 1, 1983
DOI
10.1139/o83-152
ISSN
0829-8211