Protein Kinases Concept

subject area of

• A Small Molecule Discrimination Map of the Antibiotic Resistance Kinome  Journal Articles
• A phase II clinical and pharmacodynamic study of temsirolimus in advanced neuroendocrine carcinomas  Conferences
• A vancomycin photoprobe identifies the histidine kinase VanSsc as a vancomycin receptor  Journal Articles
• AMP-Activated Protein Kinase Is Not Down-Regulated in Human Skeletal Muscle of Obese Females  Journal Articles
• AMPK β1 Deletion Reduces Appetite, Preventing Obesity and Hepatic Insulin Resistance  Journal Articles
• ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres  Journal Articles
• Active Site Interference and Asymmetric Activation in the Chemotaxis Protein Histidine Kinase CheA  Journal Articles
• Alterations in erythrocyte membrane material properties: a marker of the membrane abnormality in human and chicken muscular dystrophy.  Journal Articles
• Alterations of Membrane Phosphorylation in Erythrocyte Membranes from Patients with Duchenne Muscular Dystrophy  Journal Articles
• Alterations of erythrocyte ghost protein phosphorylation in the duchenne and myotonic muscular dystrophies  Journal Articles
• An acute bout of high-intensity interval training increases the nuclear abundance of PGC-1α and activates mitochondrial biogenesis in human skeletal muscle  Journal Articles
• Argos and Spitz group genes function to regulate midline glial cell number in Drosophila embryos  Journal Articles
• Bacterial Chemotaxis: The motor connection  Journal Articles
• Carbohydrate Does Not Augment Exercise-Induced Protein Accretion versus Protein Alone  Journal Articles
• Carbohydrate metabolism during prolonged exercise and recovery: interactions between pyruvate dehydrogenase, fatty acids, and amino acids  Journal Articles
• Characterization of an inducible vancomycin resistance system in Streptomyces coelicolor reveals a novel gene (vanK) required for drug resistance  Journal Articles
• Characterization of rcsB and rcsC from Escherichia coli O9:K30:H12 and examination of the role of the rcs regulatory system in expression of group I capsular polysaccharides  Journal Articles
• Chlamydiae Host Cell Interactions Revealed Using DNA Microarrays  Journal Articles
• Control of oxygen free radical formation from mitochondrial complex I: roles for protein kinase A and pyruvate dehydrogenase kinase  Journal Articles
• Crystal structure of an aminoglycoside 6'-N-acetyltransferase: defining the GCN5-related N-acetyltransferase superfamily fold  Journal Articles
• De Novo and Inherited Loss-of-Function Variants in TLK2: Clinical and Genotype-Phenotype Evaluation of a Distinct Neurodevelopmental Disorder  Journal Articles
• Determination of soluble CAMP-dependent protein kinase activity in guinea-pig tracheal smooth muscle  Journal Articles
• Dimerization Is Required for the Activity of the Protein Histidine Kinase CheA That Mediates Signal Transduction in Bacterial Chemotaxis  Journal Articles
• Dissociation of AMPK activity and ACCβ phosphorylation in human muscle during prolonged exercise  Journal Articles
• Drug evaluation: AP-23573--an mTOR inhibitor for the treatment of cancer.  Journal Articles
• ERK1 and ERK2 kinases activate hydroxyurea-induced S-phase checkpoint in MCF7 cells by mediating ATR activation  Journal Articles
• Effects of aerobic training on pyruvate dehydrogenase and pyruvate dehydrogenase kinase in human skeletal muscle  Journal Articles
• Effects of phosphodiesterase inhibitors on normal and chemically‐skinned isolated airway smooth muscle  Journal Articles
• Elevated n-3 fatty acids in a high-fat diet attenuate the increase in PDH kinase activity but not PDH activity in human skeletal muscle  Journal Articles
• Establishing the Principles of Recognition in the Adenine-Binding Region of an Aminoglycoside Antibiotic Kinase [APH(3‘)-IIIa]  Journal Articles
• Exercise training increases branched-chain oxoacid dehydrogenase kinase content in human skeletal muscle  Journal Articles
• Expression of cyclic-nucleotide-sensitive and -insensitive isoforms of the plasma membrane Ca2+ pump in smooth muscle and other tissues  Journal Articles
• FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in whole-body glucose homeostasis  Journal Articles
• Fatty acids stimulate AMP‐activated protein kinase and enhance fatty acid oxidation in L6 myotubes  Journal Articles
• Genetic identification of effectors downstream of Neu (ErbB-2) autophosphorylation sites in a Drosophila model  Journal Articles
• Genomic Minimalism in the Early Diverging Intestinal Parasite Giardia lamblia  Journal Articles
• Genomics of Loa loa, a Wolbachia-free filarial parasite of humans  Journal Articles
• HSV Cheats the Executioner  Journal Articles
• Human skeletal muscle PDH kinase activity and isoform expression during a 3-day high-fat/low-carbohydrate diet  Journal Articles
• Human skeletal muscle pyruvate dehydrogenase kinase activity increases after a low-carbohydrate diet  Journal Articles
• Hybrid sensor kinase PA1611 in Pseudomonas aeruginosa regulates transitions between acute and chronic infection through direct interaction with RetS  Journal Articles
• Identification of Rhizobium-specific intergenic mosaic elements within an essential two-component regulatory system of Rhizobium species  Journal Articles
• Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion  Journal Articles
• Immunoprecipitation of protein kinase activity from adenovirus 5-infected cells using antiserum directed against tumour antigens  Journal Articles
• Inflammation in Obesity is a Common Link Between Defects in Fatty Acid Metabolism and Insulin Resistance  Journal Articles
• Inhibition of Aminoglycoside Antibiotic Resistance Enzymes by Protein Kinase Inhibitors  Journal Articles
• Inhibition of sporulation, glycopeptide antibiotic production and resistance in Streptomyces toyocaensis NRRL 15009 by protein kinase inhibitors  Journal Articles
• Involvement of the actin network in insulin signalling.  Conferences
• Kinase-specific responsiveness to incremental contractile activity in skeletal muscle with low and high mitochondrial content  Journal Articles
• Leukotriene D₄ receptors are not negatively coupled to adenylyl cyclase in guinea‐pig lung parenchyma  Journal Articles
• Mitogen-activated protein kinases Erk1/2 and p38 are required for maximal regulation of TIMP-1 by oncostatin M in murine fibroblasts  Journal Articles
• Molecular Analyses of Gene Products Associated with the Response of Cells to Mitogenic Stimulation  Journal Articles
• Multiple histidines in the periplasmic domain of the Salmonella enterica sensor kinase SsrA enhance signaling in response to extracellular acidification  Journal Articles
• Muscle fiber type comparison of PDH kinase activity and isoform expression in fed and fasted rats  Journal Articles
• Myotonic muscular dystrophy  Journal Articles
• Non-digestible oligosaccharides directly regulate host kinome to modulate host inflammatory responses without alterations in the gut microbiota  Journal Articles
• Nucleotide Variation in the Egfr Locus of Drosophila melanogaster  Journal Articles
• Out‐FOX(O)ing proteolysis in sepsis  Journal Articles
• Overproduction of polyomavirus middle T antigen in mammalian cells through the use of an adenovirus vector  Journal Articles
• PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function  Journal Articles
• Phosphorylation of PITSLRE p110 Isoforms Accompanies Their Processing by Caspases during Fas-mediated Cell Death  Journal Articles
• Phosphorylation of casein by human erythrocyte membrane-bound protein kinase: competition of casein with endogenous substrates  Journal Articles
• Phylogenetic relationship and virulence inference of Streptococcus Anginosus Group: curated annotation and whole-genome comparative analysis support distinct species designation  Journal Articles
• Prognostic impact of kinase-activating fusions and IKZF1 deletions in pediatric high-risk B-lineage acute lymphoblastic leukemia  Journal Articles
• Protein kinase activity immunoprecipitated from adenovirus infected cells by sera from tumor-bearing hamsters  Journal Articles
• Protein kinase and ATP-binding activity associated with the 72-kdalton single-stranded DNA-binding protein from early region 2A of human adenovirus type 5  Journal Articles
• Purification and characterization of VanR and the cytosolic domain of VanS: A two-component regulatory system required for vancomycin resistance in Enterococcus faecium BM4147  Journal Articles
• Pyruvate overrides inhibition of PDH during exercise after a low-carbohydrate diet  Journal Articles
• Rapamycin does not prevent increases in myofibrillar or mitochondrial protein synthesis following endurance exercise  Journal Articles
• Rapid upregulation of pyruvate dehydrogenase kinase activity in human skeletal muscle during prolonged exercise  Journal Articles
• Real-time fluorogenic kinase assay using protein as substrate  Journal Articles
• Receptor domains of two-component signal transduction systems  Journal Articles
• Receptor-mediated protein kinase activation and the mechanism of transmembrane signaling in bacterial chemotaxis  Journal Articles
• Reduced AMP-activated protein kinase activity in mouse skeletal muscle does not exacerbate the development of insulin resistance with obesity  Journal Articles
• Regulation of NADH/CoQ Oxidoreductase: Do Phosphorylation Events Affect Activity?  Journal Articles
• Resistance exercise decreases eIF2Bε phosphorylation and potentiates the feeding-induced stimulation of p70^S6K1 and rpS6 in young men  Journal Articles
• Salicylate enhances the response of prostate cancer to radiotherapy  Journal Articles
• Sirolimus and mTORC1: centre stage in the story of what makes muscles bigger?  Journal Articles
• Site-directed mutagenesis of the src gene of Rous sarcoma virus: construction and characterization of a deletion mutant temperature sensitive for transformation  Journal Articles
• Site-directed point mutation in the src gene oF rous sarcoma virus results in an inactive src gene product  Journal Articles
• Skeletal muscle glucose uptake during contraction is regulated by nitric oxide and ROS independently of AMPK  Journal Articles
• Skeletal muscle metabolism is unaffected by DCA infusion and hyperoxia after onset of intense aerobic exercise  Journal Articles
• Small-Molecule Modulators of Listeria monocytogenes Biofilm Development  Journal Articles
• Specific attenuation of protein kinase phosphorylation in muscle with a high mitochondrial content  Journal Articles
• Structure of an Enzyme Required for Aminoglycoside Antibiotic Resistance Reveals Homology to Eukaryotic Protein Kinases  Journal Articles
• TATA-binding protein activates transcription when upstream of a GCN4-binding site in a novel yeast promoter.  Journal Articles
• Targeting AMP-activated protein kinase (AMPK) for treatment of autosomal dominant polycystic kidney disease  Journal Articles
• Tests for the replication of an association between Egfr and natural variation in Drosophila melanogaster wing morphology  Journal Articles
• The Mycobacterium tuberculosis DosR Regulon Assists in Metabolic Homeostasis and Enables Rapid Recovery from Nonrespiring Dormancy  Journal Articles
• The AMPK agonist 5‐aminoimidazole‐4‐carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation‐associated cachectic muscle wasting  Journal Articles
• The activity of the Ets transcription factor PEA3 is regulated by two distinct MAPK cascades.  Journal Articles
• The catalytic subunit of protein kinase A triggers activation of the type V cyclic GMP-specific phosphodiesterase from guinea-pig lung  Journal Articles
• The effect of membrane cholesterol depletion upon erythrocyte membrane-bound enzymes  Journal Articles
• The effect of methacholine and histamine on cyclic AMP-dependent protein kinase activity in the guinea-pig isolated trachea  Journal Articles
• The major site of tyrosine phosphorylation in polyomavirus middle T antigen is not required for transformation  Journal Articles
• The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue  Journal Articles
• Titin is a Target of Matrix Metalloproteinase-2  Journal Articles
• Transcriptome Profiling and Functional Analysis ofAgrobacterium tumefaciensReveals a General Conserved Response to Acidic Conditions (pH 5.5) and a Complex Acid-Mediated Signaling Involved inAgrobacterium-Plant Interactions  Journal Articles
• Transforming Proteins of Human Adenovirus 5: Studies with Infected and Transformed Cells  Journal Articles
• Two isoprenylated flavonoids from Dorstenia psilurus activate AMPK, stimulate glucose uptake, inhibit glucose production and lower glycemia  Journal Articles
• Underactivation of the adiponectin–adiponectin receptor 1 axis in clear cell renal cell carcinoma: implications for progression  Journal Articles