subject area of
- A long-term follow-up study investigating health-related quality of life and resource use in survivors of severe sepsis: comparison of recombinant human activated protein C with standard care Academic Article
- A monoclonal antibody against activated protein C allows rapid detection of activated protein C in plasma and reveals a calcium ion dependent epitope involved in factor Va inactivation Academic Article
- Acquired activated protein C resistance is associated with lupus anticoagulants and thrombotic events in pediatric patients with systemic lupus erythematosus Academic Article
- Activated Protein C Up-Regulates IL-10 and Inhibits Tissue Factor in Blood Monocytes Academic Article
- Activated Protein C in Ischemia-Reperfusion Injury After Experimental Lung Transplantation Academic Article
- Activated protein C generation is greatly decreased in plasma from newborns compared to adults in the presence or absence of endothelium Academic Article
- Activated protein C improves intestinal microcirculation in experimental endotoxaemia in the rat. Academic Article
- Activated protein C in sepsis and beyond: Update 2006 Academic Article
- Activated protein C modulates inflammation, apoptosis and tissue factor procoagulant activity by regulating endoplasmic reticulum calcium depletion in blood monocytes Academic Article
- Activation of protein C and thrombin activable fibrinolysis inhibitor on cultured human endothelial cells Academic Article
- Advances in Antithrombotic Therapy: Novel Agents Academic Article
- Characterization of mice harboring a variant of EPCR with impaired ability to bind protein C: novel role of EPCR in hematopoiesis Academic Article
- Chronic venous abnormalities in symptomatic and asymptomatic protein C deficiency Academic Article
- Comparison of 5-mg and 10-mg Loading Doses in Initiation of Warfarin Therapy Academic Article
- Comparison of N-linked glycosylation of protein C in newborns and adults Academic Article
- Continuing Challenges of Sepsis Research Academic Article
- Covalent antithrombin-heparin effect on thrombin-thrombomodulin and activated protein C reaction with factor V/Va Academic Article
- Differential Expression of PCSK9 Modulates Infection, Inflammation, and Coagulation in a Murine Model of Sepsis Academic Article
- Direct thrombin inhibitors for treatment of arterial thrombosis: potential differences between bivalirudin and hirudin Conference Paper
- Does activated protein C resistance increase the risk of systemic embolism in non rheumatic atrial fibrillation? Academic Article
- Dose-response study of recombinant human soluble thrombomodulin (ART-123) in the prevention of venous thromboembolism after total hip replacement Academic Article
- Drotrecogin alfa (activated): does current evidence support treatment for any patients with severe sepsis? Academic Article
- Effect of covalent antithrombin-heparin on activated protein C inactivation by protein C inhibitor Academic Article
- Effects of activated protein C on the mesenteric microcirculation and cytokine release during experimental endotoxemia Academic Article
- Effects of the chemotherapeutic agent doxorubicin on the protein C anticoagulant pathway Academic Article
- Endogenous protein C activation in patients with severe sepsis Academic Article
- Evidence of a Founder Effect for the Protein C Gene 3363 Inserted C Mutation in Thrombophilic Pedigrees of French Origin Academic Article
- Exosite 2-Directed Ligands Attenuate Protein C Activation by the Thrombin–Thrombomodulin Complex Academic Article
- Full or Partial Substitution of the Reactive Center Loop of α-1-Proteinase Inhibitor by that of Heparin Cofactor II: P1 Arg Is Required for Maximal Thrombin Inhibition Academic Article
- Fusion of the C-terminal triskaidecapeptide of hirudin variant 3 to alpha1-proteinase inhibitor M358R increases the serpin-mediated rate of thrombin inhibition Academic Article
- Glycosaminoglycans Bind Factor Xa in a Ca 2+ -Dependent Fashion and Modulate Its Catalytic Activity † Academic Article
- Heparin-induced thrombocytopenia and thrombosis: clinical and laboratory studies Academic Article
- Identification of the Protein C/Activated Protein C Binding Sites on the Endothelial Cell Protein C Receptor Academic Article
- Impact of Chemotherapy on Thrombin Generation and on the Protein C Pathway in Breast Cancer Patients Academic Article
- In the Presence of Phospholipids, Glycosaminoglycans Potentiate Factor Xa-Mediated Protein C Activation by Modulating Factor Xa Activity † Academic Article
- Inherited Thrombophilia in Ischemic Stroke and Its Pathogenic Subtypes Academic Article
- Low Plasma Protein C Values Predict Mortality in Low Birth Weight Neonates With Septicemia Academic Article
- Mechanisms by Which Soluble Endothelial Cell Protein C Receptor Modulates Protein C and Activated Protein C Function Academic Article
- Modulation of Monocyte Function by Activated Protein C, a Natural Anticoagulant Academic Article
- NMR Structures Reveal How Oxidation Inactivates Thrombomodulin † Academic Article
- New Anticoagulants Academic Article
- New anticoagulants Conference Paper
- No Association Between Protein C Levels and Bacteremia in Children With Febrile Neutropenia Academic Article
- Patients with severe sepsis vary markedly in their ability to generate activated protein C Academic Article
- Problems of stopping trials early Academic Article
- Prognostic utility and characterization of cell-free DNA in patients with severe sepsis Academic Article
- Protective effects of activated protein C in sepsis Academic Article
- Protein C Assay Performance Academic Article
- Protein C deficiency and thromboembolism: recurrent mutation at Arg 306 in the protein C gene Academic Article
- Resistance to activated protein C is a risk factor for fibrostenosis in Crohn’s disease Academic Article
- Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008 Academic Article
- Targeted Gene Sequencing Identifies Variants in the Protein C and Endothelial Protein C Receptor Genes in Patients With Unprovoked Venous ThromboembolismSignificance Academic Article
- The Pathogenesis of Venous Limb Gangrene Associated with Heparin-Induced Thrombocytopenia Academic Article
- The chemotherapy metabolite acrolein upregulates thrombin generation and impairs the protein C anticoagulant pathway in animal-based and cell-based models Academic Article
- The impact of the endothelial protein C receptor on thrombin generation and clot lysis Academic Article
- The plasma concentration of activated protein C appears normal in patients with haemophilia Academic Article
- Thrombin generation, ProC(®)Global, prothrombin time and activated partial thromboplastin time in thawed plasma stored for seven days and after methylene blue/light pathogen inactivation. Academic Article
- Thromboepidemiology: Identifying patients with heritable risk for thrombin-mediated thromboembolic events Academic Article
- Treatment of endothelium with the chemotherapy agent vincristine affects activated protein C generation to a greater degree in newborn plasma than in adult plasma Academic Article
- Two different missense mutations at Arg 178 of the protein C (PROC) gene causing recurrent venous thrombosis. Academic Article
- Type I protein C deficiency in French Canadians: evidence of a founder effect and association of specific protein C gene mutations with plasma protein C levels. Academic Article
- Vitamin K1 metabolism and the production of des-carboxy prothrombin and protein C in the term and premature neonate. Academic Article
- Zinc: An important cofactor in haemostasis and thrombosis Academic Article
- “ProC Global”: A functional screening test that predicts recurrent venous thromboembolism Academic Article