Protein C
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A 23bp Insertion in the Endothelial Protein C Receptor (EPCR) Gene Impairs EPCR Function Academic Article
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A long-term follow-up study investigating health-related quality of life and resource use in survivors of severe sepsis: comparison of recombinant human activated protein C with standard care Academic Article
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A monoclonal antibody against activated protein C allows rapid detection of activated protein C in plasma and reveals a calcium ion dependent epitope involved in factor Va inactivation Academic Article
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A549 Lung Epithelial Cells Synthesize Anticoagulant Molecules on the Cell Surface and Matrix and in Conditioned Media Academic Article
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Acquired activated protein C resistance is associated with lupus anticoagulants and thrombotic events in pediatric patients with systemic lupus erythematosus Academic Article
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Activated Protein C Strengthens Cardiac Tolerance to Ischemic Insults in Aging Academic Article
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Activated Protein C Up-Regulates IL-10 and Inhibits Tissue Factor in Blood Monocytes Academic Article
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Activated Protein C in Ischemia-Reperfusion Injury After Experimental Lung Transplantation Academic Article
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Activated protein C generation is greatly decreased in plasma from newborns compared to adults in the presence or absence of endothelium Academic Article
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Activated protein C improves intestinal microcirculation in experimental endotoxaemia in the rat. Academic Article
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Activated protein C in sepsis and beyond: Update 2006 Academic Article
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Activated protein C resistance, factor V Leiden and peripheral vascular disease. Academic Article
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Activated protein C modulates inflammation, apoptosis and tissue factor procoagulant activity by regulating endoplasmic reticulum calcium depletion in blood monocytes Academic Article
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Activation of protein C and thrombin activable fibrinolysis inhibitor on cultured human endothelial cells Academic Article
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Advances in Antithrombotic Therapy: Novel Agents Academic Article
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Characterization of mice harboring a variant of EPCR with impaired ability to bind protein C: novel role of EPCR in hematopoiesis Academic Article
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Chronic venous abnormalities in symptomatic and asymptomatic protein C deficiency Academic Article
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Comparison of 5-mg and 10-mg Loading Doses in Initiation of Warfarin Therapy Academic Article
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Comparison of N-linked glycosylation of protein C in newborns and adults Academic Article
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Continuing Challenges of Sepsis Research Academic Article
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Conversion of thrombin into an anticoagulant by protein engineering Academic Article
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Covalent antithrombin-heparin effect on thrombin-thrombomodulin and activated protein C reaction with factor V/Va Academic Article
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Diagnostic and prognostic accuracy of Protein C in adult patients with sepsis: protocol for a systematic review and meta-analysis Academic Article
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Differential Expression of PCSK9 Modulates Infection, Inflammation, and Coagulation in a Murine Model of Sepsis Academic Article
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Differential Gene Expression in Thrombomodulin (TM; CD141)+ and TM− Dendritic Cell Subsets Academic Article
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Direct thrombin inhibitors for treatment of arterial thrombosis: potential differences between bivalirudin and hirudin Conference Paper
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Dissociation of Thrombin's Substrate Interactions Using Site-Directed Mutagenesis Academic Article
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Does activated protein C resistance increase the risk of systemic embolism in non rheumatic atrial fibrillation? Academic Article
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Dose-response study of recombinant human soluble thrombomodulin (ART-123) in the prevention of venous thromboembolism after total hip replacement Academic Article
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Drotrecogin alfa (activated) in patients with severe sepsis and a high risk of death. Academic Article
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Drotrecogin alfa (activated): does current evidence support treatment for any patients with severe sepsis? Academic Article
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Drotrecogin alfa (activated): down and not out, but not really in either. Academic Article
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Effect of covalent antithrombin-heparin on activated protein C inactivation by protein C inhibitor Academic Article
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Effects of activated protein C on the mesenteric microcirculation and cytokine release during experimental endotoxemia Academic Article
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Effects of the chemotherapeutic agent doxorubicin on the protein C anticoagulant pathway Academic Article
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Endogenous protein C activation in patients with severe sepsis Academic Article
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Evidence of a Founder Effect for the Protein C Gene 3363 Inserted C Mutation in Thrombophilic Pedigrees of French Origin Academic Article
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Exosite 2-Directed Ligands Attenuate Protein C Activation by the Thrombin–Thrombomodulin Complex Academic Article
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Final Results of the RHAPSODY Trial: A Multi-Center, Phase 2 Trial Using a Continual Reassessment Method to Determine the Safety and Tolerability of 3K3A-APC, A Recombinant Variant of Human Activated Protein C, in Combination with Tissue Plasminogen Activ Academic Article
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Full or Partial Substitution of the Reactive Center Loop of α-1-Proteinase Inhibitor by that of Heparin Cofactor II: P1 Arg Is Required for Maximal Thrombin Inhibition Academic Article
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Functional Mapping of the Surface Residues of Human Thrombin Academic Article
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Fusion of the C-terminal triskaidecapeptide of hirudin variant 3 to alpha1-proteinase inhibitor M358R increases the serpin-mediated rate of thrombin inhibition Academic Article
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Glycosaminoglycans Bind Factor Xa in a Ca2+-Dependent Fashion and Modulate Its Catalytic Activity Academic Article
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Heparin-induced thrombocytopenia and thrombosis: clinical and laboratory studies Academic Article
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Identification of the Protein C/Activated Protein C Binding Sites on the Endothelial Cell Protein C Receptor Academic Article
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Impact of Chemotherapy on Thrombin Generation and on the Protein C Pathway in Breast Cancer Patients Academic Article
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In the Presence of Phospholipids, Glycosaminoglycans Potentiate Factor Xa-Mediated Protein C Activation by Modulating Factor Xa Activity Academic Article
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Inherited Thrombophilia in Ischemic Stroke and Its Pathogenic Subtypes Academic Article
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Low Plasma Protein C Values Predict Mortality in Low Birth Weight Neonates With Septicemia Academic Article
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Mechanisms by Which Soluble Endothelial Cell Protein C Receptor Modulates Protein C and Activated Protein C Function Academic Article
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Modulation of Monocyte Function by Activated Protein C, a Natural Anticoagulant Academic Article
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Modulation of Thrombin’s Procoagulant and Anticoagulant Properties Conference Paper
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NMR Structures Reveal How Oxidation Inactivates Thrombomodulin Academic Article
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New Anticoagulants Academic Article
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New anticoagulants Conference Paper
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No Association Between Protein C Levels and Bacteremia in Children With Febrile Neutropenia Academic Article
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Patients with severe sepsis vary markedly in their ability to generate activated protein C Academic Article
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Problems of stopping trials early Academic Article
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Prognostic utility and characterization of cell-free DNA in patients with severe sepsis Academic Article
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Protective effects of activated protein C in sepsis Academic Article
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Protein C Assay Performance Academic Article
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Protein C deficiency and thromboembolism: recurrent mutation at Arg 306 in the protein C gene Academic Article
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Protein Engineering Thrombin for Optimal Specificity and Potency of Anticoagulant Activity in Vivo Academic Article
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Should adult patients be routinely tested for heritable thrombophilia after an episode of venous thromboembolism? Academic Article
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Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008 Academic Article
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Targeted Gene Sequencing Identifies Variants in the Protein C and Endothelial Protein C Receptor Genes in Patients With Unprovoked Venous Thromboembolism Academic Article
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The Pathogenesis of Venous Limb Gangrene Associated with Heparin-Induced Thrombocytopenia Academic Article
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The chemotherapy metabolite acrolein upregulates thrombin generation and impairs the protein C anticoagulant pathway in animal-based and cell-based models Academic Article
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The impact of the endothelial protein C receptor on thrombin generation and clot lysis Academic Article
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The plasma concentration of activated protein C appears normal in patients with haemophilia Academic Article
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The prognostic utility of protein C as a biomarker for adult sepsis: a systematic review and meta-analysis Academic Article
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Thrombin Interacts with Thrombomodulin, Protein C, and Thrombin-activatable Fibrinolysis Inhibitor via Specific and Distinct Domains Academic Article
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Thrombin generation, ProC(®)Global, prothrombin time and activated partial thromboplastin time in thawed plasma stored for seven days and after methylene blue/light pathogen inactivation. Academic Article
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Thromboepidemiology: Identifying patients with heritable risk for thrombin-mediated thromboembolic events Academic Article
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Treatment of endothelium with the chemotherapy agent vincristine affects activated protein C generation to a greater degree in newborn plasma than in adult plasma Academic Article
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Two different missense mutations at Arg 178 of the protein C (PROC) gene causing recurrent venous thrombosis Academic Article
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Type I protein C deficiency in French Canadians: evidence of a founder effect and association of specific protein C gene mutations with plasma protein C levels. Academic Article
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Zinc: An important cofactor in haemostasis and thrombosis Academic Article