Platelet Activation Concept

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• A Significant Portion of the Aequorin Luminescent Signal from Stimulated Human and Rabbit Platelets is Due to Exposure of the Aequorin to Calcium in the Suspending Medium  Journal Articles
• A comparative study of platelet factor 4‐enhanced platelet activation assays for the diagnosis of heparin‐induced thrombocytopenia  Journal Articles
• A single dose of aprotinin prevents platelet hyporeactivity after coronary artery bypass graft surgery  Journal Articles
• A trypsin-like platelet protease propagates protease-activated receptor-1 cleavage and platelet activation  Journal Articles
• Activated platelets form protected zones of adhesion on fibrinogen and fibronectin-coated surfaces.  Journal Articles
• Activation of platelets by sera containing igg1 heparin-dependent antibodies: an explanation for the predominance of the Fcγrlla “low responder” (his131) gene in patients with heparin-induced thrombocytopenia  Journal Articles
• Acute coronary syndromes: a focus on thrombin.  Journal Articles
• An Overview of the Heparin-Induced Thrombocytopenia Syndrome  Journal Articles
• Antibody epitopes in vaccine-induced immune thrombotic thrombocytopaenia  Journal Articles
• Antibody-mediated platelet activation.  Journal Articles
• Antiplatelet Agents in Acute Coronary Syndromes  Journal Articles
• Antiplatelet Drugs  Journal Articles
• Antiplatelet Effect of Active Components Derived from Chinese Herbal Medicine  Journal Articles
• Atorvastatin Delays Murine Platelet Activation In Vivo Even in the Absence of Endothelial NO Synthase  Journal Articles
• Autoimmune HIT due to apheresis catheter heparin flushes for stem cell harvesting before autotransplantation for myeloma  Conferences
• Autoimmune heparin‐induced thrombocytopenia  Journal Articles
• BF061, a novel antiplatelet and antithrombotic agent targeting P2Y12 receptor and phosphodiesterase  Journal Articles
• Binding of Thrombin to the G-protein-linked Receptor, and Not to Glycoprotein Ib, Precedes Thrombin-mediated Platelet Activation  Journal Articles
• Cardiovascular Devices and Platelet Interactions  Journal Articles
• Clinical picture of heparin-induced thrombocytopenia (HIT) and its differentiation from non-HIT thrombocytopenia  Journal Articles
• Clopidogrel does not suppress blood markers of coagulation activation in aspirin-treated patients with non-ST-elevation acute coronary syndromes  Journal Articles
• Clopidogrel in acute coronary syndromes: Where are we now?  Journal Articles
• Cold‐stored leukoreduced whole blood: Extending the time between donation and filtration has minimal impact on in vitro quality  Journal Articles
• Combination of two complementary automated rapid assays for diagnosis of heparin‐induced thrombocytopenia (HIT)  Journal Articles
• Comparison of the Proinflammatory and Procoagulant Properties of Nuclear, Mitochondrial, and Bacterial DNA  Journal Articles
• Coordinate Activation of Human Platelet Protease-activated Receptor-1 and -4 in Response to Subnanomolar α-Thrombin  Journal Articles
• Covalently linking heparin to antithrombin enhances prothrombinase inhibition on activated platelets  Journal Articles
• Dark Chocolate Effect on Platelet Activity, C-Reactive Protein and Lipid Profile: A Pilot Study  Journal Articles
• Delayed-Onset Heparin-Induced Thrombocytopenia and Thrombosis  Journal Articles
• Determinants of donor platelet variability when testing for heparin-induced thrombocytopenia.  Journal Articles
• Development of a high-yield expression and purification system for platelet factor 4  Journal Articles
• Diagnosis of suspected inherited platelet function disorders: results of a worldwide survey  Journal Articles
• Diannexin, an annexin A5 homodimer, binds phosphatidylserine with high affinity and is a potent inhibitor of platelet‐mediated events during thrombus formation  Journal Articles
• Distinguishing between anti–platelet factor 4/heparin antibodies that can and cannot cause heparin‐induced thrombocytopenia  Journal Articles
• Dual Pathway Inhibition for Vascular Protection in Patients with Atherosclerotic Disease: Rationale and Review of the Evidence  Journal Articles
• Early‐onset and persisting thrombocytopenia in post‐cardiac surgery patients is rarely due to heparin‐induced thrombocytopenia, even when antibody tests are positive  Journal Articles
• Effect of Atrial Fibrillation on Atrial Thrombogenesis in Humans: Impact of Rate and Rhythm  Journal Articles
• Effect of C4-, C8- and C18- alkylation of poly(vinyl alcohol) hydrogels on the adsorption of albumin and fibrinogen from buffer and plasma: limited correlation with platelet interactions  Journal Articles
• Effect of fondaparinux on platelet activation in the presence of heparin-dependent antibodies: a blinded comparative multicenter study with unfractionated heparin  Journal Articles
• Effect of recombinant factor VIIa on melagatran-induced inhibition of thrombin generation and platelet activation in healthy volunteers  Journal Articles
• Effects of ticagrelor versus clopidogrel on platelet function in fibrinolytic-treated STEMI patients undergoing early PCI  Journal Articles
• Endothelial and Platelet Activation in Acute Ischemic Stroke and Its Etiological Subtypes  Journal Articles
• Enhanced antiplatelet effect of clopidogrel in patients whose platelets are least inhibited by aspirin: a randomized crossover trial  Journal Articles
• Factor V Is Complexed with Multimerin in Resting Platelet Lysates and Colocalizes with Multimerin in Platelet α-Granules  Journal Articles
• Failure of Aspirin to Prevent Atherothrombosis  Journal Articles
• FcγRIIa proteolysis as a diagnostic biomarker for heparin-induced thrombocytopenia  Journal Articles
• Fibronectin modulates formation of PF4/heparin complexes and is a potential factor for reducing risk of developing HIT  Journal Articles
• Formation of anti–platelet factor 4/heparin antibodies after cardiac surgery: Influence of perioperative platelet activation, the inflammatory response, and histocompatibility leukocyte antigen status  Journal Articles
• Frequency of positive anti-PF4/polyanion antibody tests after COVID-19 vaccination with ChAdOx1 nCoV-19 and BNT162b2  Journal Articles
• HIT complicating fondaparinux prophylaxis: fondaparinux-dependent platelet activation as a marker for fondaparinux- induced HIT  Journal Articles
• HIT paradigms and paradoxes  Journal Articles
• HITlights: A career perspective on heparin‐induced thrombocytopenia  Journal Articles
• HUMAN PLATELET THROMBIN RECEPTORS  Journal Articles
• Heparin and Platelets  Journal Articles
• Heparin-Induced Thrombocytopenia  Journal Articles
• Heparin-Induced Thrombocytopenia  Journal Articles
• Heparin-Induced Thrombocytopenia Associated with Fondaparinux  Journal Articles
• Heparin-Induced Thrombocytopenia: A Clinicopathologic Syndrome  Journal Articles
• Heparin-Induced Thrombocytopenia: A Ten-Year Retrospective  Journal Articles
• Heparin-Induced thrombocytopenia: IgG-Mediated platelet activation, platelet microparticle generation, and altered procoagulant/anticoagulant balance in the pathogenesis of thrombosis and venous limb gangrene complicating heparin-Induced thrombocytopenia  Journal Articles
• Heparin-induced thrombocytopenia: A stoichiometry-based model to explain the differing immunogenicities of unfractionated heparin, low-molecular-weight heparin, and fondaparinux in different clinical settings  Journal Articles
• Heparin-induced thrombocytopenia: a historical perspective  Journal Articles
• Heparin‐induced skin lesions  Journal Articles
• Heparin‐induced thrombocytopenia – therapeutic concentrations of danaparoid, unlike fondaparinux and direct thrombin inhibitors, inhibit formation of platelet factor 4–heparin complexes  Journal Articles
• Heparin‐induced thrombocytopenia: a prospective study on the incidence, platelet‐activating capacity and clinical significance of antiplatelet factor 4/heparin antibodies of the IgG, IgM, and IgA classes  Journal Articles
• Heparin‐induced thrombocytopenia: pathogenesis and management  Journal Articles
• High-dose intravenous immunoglobulin for the treatment and prevention of heparin-induced thrombocytopenia: a review  Journal Articles
• High‐dose intravenous immunoglobulin to treat spontaneous heparin‐induced thrombocytopenia syndrome  Journal Articles
• How I Diagnose and Manage HIT  Journal Articles
• How I treat patients with a history of heparin-induced thrombocytopenia  Journal Articles
• Immune heparin-induced thrombocytopenia can occur in patients receiving clopidogrel and aspirin  Journal Articles
• In vitro evaluation of prestorage pooled leukoreduced whole blood–derived platelets stored for up to 7 days  Journal Articles
• Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia  Journal Articles
• Intensified antiplatelet therapy in patients after percutaneous coronary intervention with high on‐treatment platelet reactivity: the OPTImal Management of Antithrombotic Agents (OPTIMA)‐2 Trial  Journal Articles
• Intravenous Immune Globulin to Prevent Heparin-Induced Thrombocytopenia  Journal Articles
• Investigation of the mechanisms of monoclonal antibody-induced platelet activation  Journal Articles
• Laboratory diagnosis of heparin‐induced thrombocytopenia  Journal Articles
• Laboratory testing for heparin-induced thrombocytopenia.  Journal Articles
• Lessons from vaccine-induced immune thrombotic thrombocytopenia  Journal Articles
• Management of heparin-induced thrombocytopenia  Journal Articles
• Measurement of fibrinogen binding to platelets in whole blood by flow cytometry: a micromethod for the detection of platelet activation  Journal Articles
• Measurement of soluble P‐selectin and soluble CD40 ligand in serum and plasma  Journal Articles
• Mitochondrial-mediated inflammation and platelet activation in giant cell arteritis  Journal Articles
• Morphological analysis of microparticle generation in heparin-induced thrombocytopenia  Journal Articles
• Multicentre evaluation of 5B9, a monoclonal anti‐PF4/heparin IgG mimicking human HIT antibodies, as an internal quality control in HIT functional assays: Communication from the ISTH SSC Subcommittee on Platelet Immunology  Journal Articles
• Multimerin 1  Journal Articles
• New Approaches to the Diagnosis of Heparin-Induced Thrombocytopenia  Journal Articles
• Nonheparin Anticoagulants for Heparin-Induced Thrombocytopenia  Journal Articles
• PF4‐dependent immunoassays and inferential detection of HIT antibodies  Journal Articles
• Panax notoginseng saponin is superior to aspirin in inhibiting platelet adhesion to injured endothelial cells through COX pathway in vitro  Journal Articles
• Plasma exchange to remove HIT antibodies: dissociation between enzyme-immunoassay and platelet activation test reactivities  Journal Articles
• Plasmin accelerates platelet‐dependent prothrombinase formation without activating the platelets  Journal Articles
• Platelet Accumulation on Fibrin-coated Polyethylene: Role of Platelet Activation and Factor XIII \textbar Request PDF  Journal Articles
• Platelet Activation Testing for Heparin-Induced Thrombocytopenia Antibodies  Journal Articles
• Platelet activation and hypercoagulability following treatment with porcine factor VIII (HYATE:C)  Journal Articles
• Platelet activation induced by porcine factor VIII (HYATE:C)  Journal Articles
• Platelet-Activating Antibodies Are Detectable at the Earliest Onset of Heparin-Induced Thrombocytopenia, With Implications for the Operating Characteristics of the Serotonin-Release Assay  Journal Articles
• Platelet-leukocyte aggregation under shear stress: Differential involvement of selectins and integrins  Journal Articles
• Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration  Journal Articles
• Prevalence and clinical implications of anti-PF4/heparin antibodies in intensive care patients: a prospective observational study  Journal Articles
• Prognostic significance of platelet and microvessel counts in operable non-small cell lung cancer  Journal Articles
• Prolonged Expression of Procoagulant Activity of Human Platelets Degranulated by Thrombin  Journal Articles
• Protamine (heparin)‐induced thrombocytopenia: a review of the serological and clinical features associated with anti‐protamine/heparin antibodies  Journal Articles
• Protease activated receptors 1 and 4 govern the responses of human platelets to thrombin  Journal Articles
• Prothrombotic Effects of Hyperhomocysteinemia and Hypercholesterolemia in ApoE-Deficient Mice  Journal Articles
• Quantitative interpretation of optical density measurements using PF4‐dependent enzyme‐immunoassays  Journal Articles
• Rabbit lung macrophages stimulate platelets in vitro as observed by density-gradient centrifugation and transmission electron microscopy  Other
• Reasons for resistance to aspirin in cardiovascular disease.  Journal Articles
• Rivaroxaban plus aspirin for cardiovascular protection: Rationale for the vascular dose and dual pathway inhibition  Journal Articles
• Rivaroxaban with or without aspirin for prevention of cardiovascular disease  Journal Articles
• Role of Secreted Adenosine Diphosphate in the Synergistic Effects of Cathepsin G on Human Platelets  Journal Articles
• SARS-CoV-2 spike-dependent platelet activation in COVID-19 vaccine-induced thrombocytopenia  Journal Articles
• Serotonin‐release assay‐positive but platelet factor 4‐dependent enzyme‐immunoassay negative: HIT or not HIT?  Journal Articles
• Serum-induced platelet procoagulant activity: An assay for the characterization of prothrombotic disorders  Journal Articles
• Short- and long-term oral antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention  Journal Articles
• Streptokinase and rt-PA activate platelets by a different way: implications on the rethrombosis rate after their administration in myocardial infarction.  Journal Articles
• The COVID Complex: A Review of Platelet Activation and Immune Complexes in COVID-19  Journal Articles
• The Effects of Steroids on Coagulation Dysfunction Induced by Cardiopulmonary Bypass: A Steroids in Cardiac Surgery (SIRS) Trial Substudy  Journal Articles
• The association between platelet activation and FcγRIIa proteolysis  Journal Articles
• The functions of the A1A2A3 domains in von Willebrand factor include multimerin 1 binding  Journal Articles
• The impact of Gam-COVID-Vac, an Adv5/Adv26 COVID-19 vaccine, on the biomarkers of endothelial function, coagulation and platelet activation  Journal Articles
• The mechanism of action of thrombin inhibitors.  Journal Articles
• The role of fluid-phase immune complexes in the pathogenesis of heparin-induced thrombocytopenia  Journal Articles
• The role of microRNAs in prethrombotic status associated with coronary artery disease  Journal Articles
• The role of platelets and platelet inhibition in acute myocardial infarction  Journal Articles
• Thrombin binding to platelets and their activation in plasma  Journal Articles
• Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination  Journal Articles
• Thrombus formation: direct real-time observation and digital analysis of thrombus assembly in a living mouse by confocal and widefield intravital microscopy  Journal Articles
• Update on platelet procoagulant mechanisms in health and in bleeding disorders  Journal Articles
• Zinc delays clot lysis by attenuating plasminogen activation and plasmin-mediated fibrin degradation  Journal Articles
• p-155, a multimeric platelet protein that is expressed on activated platelets.  Journal Articles