Platelet Activation Concept

subject area of

• A Significant Portion of the Aequorin Luminescent Signal from Stimulated Human and Rabbit Platelets is Due to Exposure of the Aequorin to Calcium in the Suspending Medium  Academic Article
• A comparative study of platelet factor 4‐enhanced platelet activation assays for the diagnosis of heparin‐induced thrombocytopenia  Academic Article
• A single dose of aprotinin prevents platelet hyporeactivity after coronary artery bypass graft surgery  Academic Article
• A trypsin-like platelet protease propagates protease-activated receptor-1 cleavage and platelet activation  Academic Article
• Activated platelets form protected zones of adhesion on fibrinogen and fibronectin-coated surfaces.  Academic Article
• Activation of platelets by sera containing igg1 heparin-dependent antibodies: an explanation for the predominance of the Fcγrlla “low responder” (his131) gene in patients with heparin-induced thrombocytopenia  Academic Article
• Acute coronary syndromes: a focus on thrombin.  Academic Article
• An Overview of the Heparin-Induced Thrombocytopenia Syndrome  Academic Article
• Antibody epitopes in vaccine-induced immune thrombotic thrombocytopaenia  Academic Article
• Antibody-mediated platelet activation.  Academic Article
• Antiplatelet Agents in Acute Coronary Syndromes  Academic Article
• Antiplatelet Drugs  Academic Article
• Antiplatelet Effect of Active Components Derived from Chinese Herbal Medicine  Academic Article
• Atorvastatin Delays Murine Platelet Activation In Vivo Even in the Absence of Endothelial NO Synthase  Academic Article
• Autoimmune HIT due to apheresis catheter heparin flushes for stem cell harvesting before autotransplantation for myeloma  Conference Paper
• Autoimmune heparin‐induced thrombocytopenia  Academic Article
• BF061, a novel antiplatelet and antithrombotic agent targeting P2Y12 receptor and phosphodiesterase  Academic Article
• Binding of Thrombin to the G-protein-linked Receptor, and Not to Glycoprotein Ib, Precedes Thrombin-mediated Platelet Activation  Academic Article
• Cardiovascular Devices and Platelet Interactions  Academic Article
• Clinical picture of heparin-induced thrombocytopenia (HIT) and its differentiation from non-HIT thrombocytopenia  Academic Article
• Clopidogrel does not suppress blood markers of coagulation activation in aspirin-treated patients with non-ST-elevation acute coronary syndromes  Academic Article
• Clopidogrel in acute coronary syndromes: Where are we now?  Academic Article
• Cold‐stored leukoreduced whole blood: Extending the time between donation and filtration has minimal impact on in vitro quality  Academic Article
• Combination of two complementary automated rapid assays for diagnosis of heparin‐induced thrombocytopenia (HIT)  Academic Article
• Comparison of the Proinflammatory and Procoagulant Properties of Nuclear, Mitochondrial, and Bacterial DNA  Academic Article
• Coordinate Activation of Human Platelet Protease-activated Receptor-1 and -4 in Response to Subnanomolar α-Thrombin  Academic Article
• Covalently linking heparin to antithrombin enhances prothrombinase inhibition on activated platelets  Academic Article
• Dark Chocolate Effect on Platelet Activity, C-Reactive Protein and Lipid Profile: A Pilot Study  Academic Article
• Delayed-Onset Heparin-Induced Thrombocytopenia and Thrombosis  Academic Article
• Determinants of donor platelet variability when testing for heparin-induced thrombocytopenia.  Academic Article
• Development of a high-yield expression and purification system for platelet factor 4  Academic Article
• Diagnosis of suspected inherited platelet function disorders: results of a worldwide survey  Academic Article
• Diannexin, an annexin A5 homodimer, binds phosphatidylserine with high affinity and is a potent inhibitor of platelet‐mediated events during thrombus formation  Academic Article
• Distinguishing between anti–platelet factor 4/heparin antibodies that can and cannot cause heparin‐induced thrombocytopenia  Academic Article
• Dual Pathway Inhibition for Vascular Protection in Patients with Atherosclerotic Disease: Rationale and Review of the Evidence  Academic Article
• Early‐onset and persisting thrombocytopenia in post‐cardiac surgery patients is rarely due to heparin‐induced thrombocytopenia, even when antibody tests are positive  Academic Article
• Effect of Atrial Fibrillation on Atrial Thrombogenesis in Humans: Impact of Rate and Rhythm  Academic Article
• Effect of C4-, C8- and C18- alkylation of poly(vinyl alcohol) hydrogels on the adsorption of albumin and fibrinogen from buffer and plasma: limited correlation with platelet interactions  Academic Article
• Effect of fondaparinux on platelet activation in the presence of heparin-dependent antibodies: a blinded comparative multicenter study with unfractionated heparin  Academic Article
• Effect of recombinant factor VIIa on melagatran-induced inhibition of thrombin generation and platelet activation in healthy volunteers  Academic Article
• Effects of ticagrelor versus clopidogrel on platelet function in fibrinolytic-treated STEMI patients undergoing early PCI  Academic Article
• Endothelial and Platelet Activation in Acute Ischemic Stroke and Its Etiological Subtypes  Academic Article
• Enhanced antiplatelet effect of clopidogrel in patients whose platelets are least inhibited by aspirin: a randomized crossover trial  Academic Article
• Factor V Is Complexed with Multimerin in Resting Platelet Lysates and Colocalizes with Multimerin in Platelet α-Granules  Academic Article
• Failure of Aspirin to Prevent Atherothrombosis  Academic Article
• FcγRIIa proteolysis as a diagnostic biomarker for heparin-induced thrombocytopenia  Academic Article
• Fibronectin modulates formation of PF4/heparin complexes and is a potential factor for reducing risk of developing HIT  Academic Article
• Formation of anti–platelet factor 4/heparin antibodies after cardiac surgery: Influence of perioperative platelet activation, the inflammatory response, and histocompatibility leukocyte antigen status  Academic Article
• Frequency of positive anti-PF4/polyanion antibody tests after COVID-19 vaccination with ChAdOx1 nCoV-19 and BNT162b2  Academic Article
• HIT complicating fondaparinux prophylaxis: fondaparinux-dependent platelet activation as a marker for fondaparinux- induced HIT  Academic Article
• HIT paradigms and paradoxes  Academic Article
• HITlights: A career perspective on heparin-induced thrombocytopenia  Academic Article
• HUMAN PLATELET THROMBIN RECEPTORS  Academic Article
• Haemolytic uraemic syndrome is an immune-mediated disease: role of anti-CD36 antibodies  Academic Article
• Heparin and Platelets  Academic Article
• Heparin-Induced Thrombocytopenia  Academic Article
• Heparin-Induced Thrombocytopenia  Academic Article
• Heparin-Induced Thrombocytopenia Associated with Fondaparinux  Academic Article
• Heparin-Induced Thrombocytopenia: A Clinicopathologic Syndrome  Academic Article
• Heparin-Induced Thrombocytopenia: A Ten-Year Retrospective  Academic Article
• Heparin-Induced thrombocytopenia: IgG-Mediated platelet activation, platelet microparticle generation, and altered procoagulant/anticoagulant balance in the pathogenesis of thrombosis and venous limb gangrene complicating heparin-Induced thrombocytopenia  Academic Article
• Heparin-induced thrombocytopenia: A stoichiometry-based model to explain the differing immunogenicities of unfractionated heparin, low-molecular-weight heparin, and fondaparinux in different clinical settings  Academic Article
• Heparin-induced thrombocytopenia: a historical perspective  Academic Article
• Heparin-induced thrombocytopenia: pathogenesis and management  Academic Article
• Heparin‐induced skin lesions  Academic Article
• Heparin‐induced thrombocytopenia – therapeutic concentrations of danaparoid, unlike fondaparinux and direct thrombin inhibitors, inhibit formation of platelet factor 4–heparin complexes  Academic Article
• Heparin‐induced thrombocytopenia: a prospective study on the incidence, platelet‐activating capacity and clinical significance of antiplatelet factor 4/heparin antibodies of the IgG, IgM, and IgA classes  Academic Article
• High-dose intravenous immunoglobulin for the treatment and prevention of heparin-induced thrombocytopenia: a review  Academic Article
• High‐dose intravenous immunoglobulin to treat spontaneous heparin‐induced thrombocytopenia syndrome  Academic Article
• How I Diagnose and Manage HIT  Academic Article
• How I treat patients with a history of heparin-induced thrombocytopenia  Academic Article
• Immune heparin-induced thrombocytopenia can occur in patients receiving clopidogrel and aspirin  Academic Article
• In vitro evaluation of prestorage pooled leukoreduced whole blood-derived platelets stored for up to 7 days  Academic Article
• Influenza virus H1N1 activates platelets through FcγRIIA signaling and thrombin generation  Academic Article
• Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia  Academic Article
• Intensified antiplatelet therapy in patients after percutaneous coronary intervention with high on‐treatment platelet reactivity: the OPTImal Management of Antithrombotic Agents (OPTIMA)‐2 Trial  Academic Article
• Intravenous Immune Globulin to Prevent Heparin-Induced Thrombocytopenia  Academic Article
• Investigation of the mechanisms of monoclonal antibody-induced platelet activation  Academic Article
• Laboratory diagnosis of heparin‐induced thrombocytopenia  Academic Article
• Laboratory testing for heparin-induced thrombocytopenia.  Academic Article
• Lessons from vaccine-induced immune thrombotic thrombocytopenia  Academic Article
• Management of heparin-induced thrombocytopenia  Academic Article
• Measurement of fibrinogen binding to platelets in whole blood by flow cytometry: a micromethod for the detection of platelet activation  Academic Article
• Measurement of soluble P‐selectin and soluble CD40 ligand in serum and plasma  Academic Article
• Morphological analysis of microparticle generation in heparin-induced thrombocytopenia  Academic Article
• Multicentre evaluation of 5B9, a monoclonal anti‐PF4/heparin IgG mimicking human HIT antibodies, as an internal quality control in HIT functional assays: Communication from the ISTH SSC Subcommittee on Platelet Immunology  Academic Article
• Multimerin 1  Academic Article
• New Approaches to the Diagnosis of Heparin-Induced Thrombocytopenia  Academic Article
• Nonheparin Anticoagulants for Heparin-Induced Thrombocytopenia  Academic Article
• PF4‐dependent immunoassays and inferential detection of HIT antibodies  Academic Article
• Panax notoginseng saponin is superior to aspirin in inhibiting platelet adhesion to injured endothelial cells through COX pathway in vitro  Academic Article
• Plasma exchange to remove HIT antibodies: dissociation between enzyme-immunoassay and platelet activation test reactivities  Academic Article
• Plasmin accelerates platelet‐dependent prothrombinase formation without activating the platelets  Academic Article
• Platelet Accumulation on Fibrin-coated Polyethylene: Role of Platelet Activation and Factor XIII \textbar Request PDF  Academic Article
• Platelet Activation Testing for Heparin-Induced Thrombocytopenia Antibodies  Academic Article
• Platelet activation and hypercoagulability following treatment with porcine factor VIII (HYATE:C)  Academic Article
• Platelet activation induced by porcine factor VIII (HYATE:C)  Academic Article
• Platelet-Activating Antibodies Are Detectable at the Earliest Onset of Heparin-Induced Thrombocytopenia, With Implications for the Operating Characteristics of the Serotonin-Release Assay  Academic Article
• Platelet-leukocyte aggregation under shear stress: Differential involvement of selectins and integrins  Academic Article
• Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration  Academic Article
• Prevalence and clinical implications of anti-PF4/heparin antibodies in intensive care patients: a prospective observational study  Academic Article
• Prognostic significance of platelet and microvessel counts in operable non-small cell lung cancer  Academic Article
• Prolonged Expression of Procoagulant Activity of Human Platelets Degranulated by Thrombin  Academic Article
• Protamine (heparin)‐induced thrombocytopenia: a review of the serological and clinical features associated with anti‐protamine/heparin antibodies  Academic Article
• Protease activated receptors 1 and 4 govern the responses of human platelets to thrombin  Academic Article
• Prothrombotic Effects of Hyperhomocysteinemia and Hypercholesterolemia in ApoE-Deficient Mice  Academic Article
• Quantitative interpretation of optical density measurements using PF4‐dependent enzyme‐immunoassays  Academic Article
• Rabbit lung macrophages stimulate platelets in vitro as observed by density-gradient centrifugation and transmission electron microscopy  Article
• Reasons for resistance to aspirin in cardiovascular disease.  Academic Article
• Rivaroxaban plus aspirin for cardiovascular protection: Rationale for the vascular dose and dual pathway inhibition  Academic Article
• Rivaroxaban with or without aspirin for prevention of cardiovascular disease  Academic Article
• Role of Secreted Adenosine Diphosphate in the Synergistic Effects of Cathepsin G on Human Platelets  Academic Article
• SARS-CoV-2 spike-dependent platelet activation in COVID-19 vaccine-induced thrombocytopenia  Academic Article
• Serotonin‐release assay‐positive but platelet factor 4‐dependent enzyme‐immunoassay negative: HIT or not HIT?  Academic Article
• Serum-induced platelet procoagulant activity: An assay for the characterization of prothrombotic disorders  Academic Article
• Short- and long-term oral antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention  Academic Article
• Site of Action for the Inhibition by Gold Sodium Thiomalate of Rabbit Platelet Activation  Academic Article
• Streptokinase and rt-PA activate platelets by a different way: implications on the rethrombosis rate after their administration in myocardial infarction.  Academic Article
• The COVID Complex: A Review of Platelet Activation and Immune Complexes in COVID-19  Academic Article
• The Effects of Steroids on Coagulation Dysfunction Induced by Cardiopulmonary Bypass: A Steroids in Cardiac Surgery (SIRS) Trial Substudy  Academic Article
• The association between platelet activation and FcγRIIa proteolysis  Academic Article
• The functions of the A1A2A3 domains in von Willebrand factor include multimerin 1 binding  Academic Article
• The mechanism of action of thrombin inhibitors.  Academic Article
• The role of fluid-phase immune complexes in the pathogenesis of heparin-induced thrombocytopenia  Academic Article
• The role of microRNAs in prethrombotic status associated with coronary artery disease  Academic Article
• The role of platelets and platelet inhibition in acute myocardial infarction  Academic Article
• Thrombin binding to platelets and their activation in plasma  Academic Article
• Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination  Academic Article
• Thrombus formation: direct real-time observation and digital analysis of thrombus assembly in a living mouse by confocal and widefield intravital microscopy  Academic Article
• Update on platelet procoagulant mechanisms in health and in bleeding disorders  Academic Article
• Zinc delays clot lysis by attenuating plasminogen activation and plasmin-mediated fibrin degradation  Academic Article
• p-155, a multimeric platelet protein that is expressed on activated platelets.  Academic Article