Imidazoles Concept

subject area of

• 1-phenyl-5-vinyl-2-imidazolidinethione, a proposed causative agent of Spanish toxic oil syndrome: Synthesis, and identification in one of a group of case-associated oil samples  Journal Articles
• 24-hour intragastric acidity and nocturnal acid secretion in patients with duodenal ulcer during oral administration of cimetidine and atropine.  Journal Articles
• A community-based clinical trial of Intra-Venous zOledRonic acid once Yearly in comparison to oral bisphosphonates in postmenopausal women with osteoporosis: The IVORY trial  Journal Articles
• A phase I dose-ranging trial of monthly infusions of zoledronic acid for the treatment of osteolytic bone metastases.  Journal Articles
• A phase III trial of tirasemtiv as a potential treatment for amyotrophic lateral sclerosis  Journal Articles
• AT ₁ Receptor Antagonist Treatment Caused Persistent Arterial Functional Changes in Young Spontaneously Hypertensive Rats  Journal Articles
• Activation of p38 mitogen-activated protein kinase during normal mitosis in the developing retina  Journal Articles
• Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release  Journal Articles
• Alteration of H2 receptor sensitivity in duodenal ulcer patients after maintenance treatment with an H2 receptor antagonist.  Journal Articles
• Antifracture Efficacy and Reduction of Mortality in Relation to Timing of the First Dose of Zoledronic Acid After Hip Fracture  Journal Articles
• Antineoplastic Agents. 362. Isolation and X-ray Crystal Structure of Dibromophakellstatin from the Indian Ocean Sponge Phakellia mauritiana  Journal Articles
• Association between timing of zoledronic acid infusion and hip fracture healing  Journal Articles
• Atomic resolution structure of obelin: soaking with calcium enhances electron density of the second oxygen atom substituted at the C2-position of coelenterazine  Journal Articles
• BMS-214662 induces mitochondrial apoptosis in chronic myeloid leukemia (CML) stem/progenitor cells, including CD34+38− cells, through activation of protein kinase Cβ  Journal Articles
• Bisphosphonate-Induced Orbital Inflammation: A Case Series and Review  Journal Articles
• Bone Health and Bone-targeted Therapies for Prostate Cancer: a Programme in Evidence-based Care — Cancer Care Ontario Clinical Practice Guideline  Journal Articles
• Bone Turnover Markers as Predictors of Skeletal Complications in Prostate Cancer, Lung Cancer, and Other Solid Tumors  Journal Articles
• Capacitative Ca2+ entry in HL-60 cells: tetrandrine and SK & F 96365 as probes.  Journal Articles
• Cellular approaches for diagnostic effects assessment in ecotoxicology: introductory remarks to an EU-funded project  Journal Articles
• Changes in cross‐sectional geometry of the distal femoral metaphysis associated with inflammatory arthritis are reduced by a bisphosphonate (zoledronate)  Journal Articles
• Clinical Risk Factors for Recurrent Fracture after Hip Fracture: A Prospective Study  Journal Articles
• Clinical Utility of Biochemical Markers of Bone Metabolism for Improving the Management of Patients with Advanced Multiple Myeloma  Journal Articles
• Clinical evaluation of the efficacy and safety of noberastine, a new H1 antagonist, in seasonal allergic rhinitis: A placebo-controlled, dose-response study  Journal Articles
• Clorgyline-induced switch from locomotion to mouthing in sensitization to the dopamine D2/D3 agonist quinpirole in rats: role of sigma and imidazoline I2 receptors  Journal Articles
• Comparison of the effects of gastric antisecretory agents in healthy volunteers and patients with duodenal ulcer.  Journal Articles
• Control of oxygen free radical formation from mitochondrial complex I: roles for protein kinase A and pyruvate dehydrogenase kinase  Journal Articles
• Cost-effectiveness of daclatasvir plus sofosbuvir-based regimen for treatment of hepatitis C virus genotype 3 infection in Canada  Journal Articles
• Covalent Immune Recruiters: Tools to Gain Chemical Control Over Immune Recognition  Journal Articles
• Cross-over study comparing effects of treatment with an angiotensin converting enzyme inhibitor and an angiotensin II type 1 receptor antagonist on cardiovascular changes in hypertension  Journal Articles
• Current Perspectives in the Pharmacological Studies of Store-Operated Ca2+ Entry Blockers.  Journal Articles
• Dual effects of SK&F 96365 in human leukemic HL-60 cells  Journal Articles
• Editorial: healing of refractory reflux oesophagitis – an ongoing unmet clinical need  Journal Articles
• Editorial: potassium‐competitive acid blockers for acid‐related diseases—tegoprazan, a new kid on the block  Journal Articles
• Effect of bisphosphonates on pain and quality of life in patients with bone metastases  Journal Articles
• Effect of zoledronic acid on the doxycycline-induced decrease in tumour burden in a bone metastasis model of human breast cancer  Journal Articles
• Effect on Intragastric pH of a PPI with a Prolonged Plasma Half-Life: Comparison between Tenatoprazole and Esomeprazole on the Duration of Acid Suppression in Healthy Male Volunteers  Journal Articles
• Effects of phosphodiesterase inhibitors on normal and chemically‐skinned isolated airway smooth muscle  Journal Articles
• Effects of pumaprazole (BY841), a novel reversible proton pump antagonist, and of omeprazole, on intragastric acidity before and after cure of Helicobacter pylori infection  Journal Articles
• Efficacy and safety of a once-yearly i.v. Infusion of zoledronic acid 5 mg versus a once-weekly 70-mg oral alendronate in the treatment of male osteoporosis: A randomized, multicenter, double-blind, active-controlled study  Journal Articles
• Efficacy of Bisphosphonates in the Management of Skeletal Complications of Bone Metastases and Selection of Clinical Endpoints  Journal Articles
• Efficacy of bisphosphonates in the management of skeletal complications of bone metastases and selection of clinical endpoints.  Journal Articles
• Electrochemical detection of 4(5)-methylimidazole in aqueous solutions  Journal Articles
• Experience with ponatinib in paediatric patients with leukaemia  Journal Articles
• Gastric secretory studies in humans with impromidine (SK&F 92676)—a specific histamine H2 receptor agonist  Journal Articles
• Glucose transporter expression in L6 muscle cells: Regulation through insulin- and stress-activated pathways  Journal Articles
• HEALING OF GASTRIC ULCER DURING TREATMENT WITH CIMETIDINE  Journal Articles
• HR 720, a novel angiotensin receptor antagonist inhibits the angiotensin II-induced trophic effects, fibronectin release and fibronectin-EIIIA+ expression in rat aortic vascular smooth muscle cells in vitro.  Journal Articles
• High-affinity pH-dependent passive Ca binding by myometrial plasma membrane vesicles  Journal Articles
• Histamine H₂Receptors and Intrinsic Factor Secretion  Journal Articles
• Hplc/Electrospray Ionization Mass Spectrometric Analysis of the Heterocyclic Aromatic Amine Carcinogen 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Human Milk  Journal Articles
• Human airway smooth muscle promotes eosinophil differentiation  Journal Articles
• Imidazole-Based [2 + 1] Re(I)/^99mTc(I) Complexes as Isostructural Nuclear and Optical Probes  Journal Articles
• Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development  Journal Articles
• Inhibition of smooth muscle 5′-nucleotidase by imidazole and its reversal by magnesium  Journal Articles
• Inhibition of the colony-stimulating-factor-1 receptor affects the resistance of lung cancer cells to cisplatin  Journal Articles
• Markers of Bone Metabolism and Survival in Men with Hormone-Refractory Metastatic Prostate Cancer  Journal Articles
• Melatonin triggers p53Ser phosphorylation and prevents DNA damage accumulation  Journal Articles
• Network meta-analysis of therapies for previously untreated advanced BRAF-mutated melanoma  Journal Articles
• Nitric oxide modulates mechanical strain-induced activation of p38 MAPK in mesangial cells  Journal Articles
• Normalization of bone markers is associated with improved survival in patients with bone metastases from solid tumors and elevated bone resorption receiving zoledronic acid  Journal Articles
• Once-Yearly Zoledronic Acid in Older Men Compared with Women with Recent Hip Fracture  Journal Articles
• Ondansetron; further progress in the prevention of nausea and vomiting induced by anti-cancer chemotherapy  Journal Articles
• Optimal management of metastatic bone disease  Journal Articles
• Optimal management of metastatic bone disease  Journal Articles
• Oral bisphosphonates  Journal Articles
• Oxmetidine: clinical pharmacological studies with a new H2-receptor antagonist.  Journal Articles
• Patient Management, and Time and Health Care Resource Utilization Associated with the Use of Intravenous Bisphosphonates For Patients with Metastatic Bone Disease: A Delphi Study  Journal Articles
• Phase 2 Study of Erlotinib in Combination With Linsitinib (OSI-906) or Placebo in Chemotherapy-Naive Patients With Non–Small-Cell Lung Cancer and Activating Epidermal Growth Factor Receptor Mutations  Journal Articles
• Phase 2 study evaluating intermittent and continuous linsitinib and weekly paclitaxel in patients with recurrent platinum resistant ovarian epithelial cancer  Journal Articles
• Phase I Dose-Escalation Study of Linsitinib (OSI-906) and Erlotinib in Patients with Advanced Solid Tumors  Journal Articles
• Plant alkaloids, tetrandrine and hernandezine, inhibit calcium-depletion stimulated calcium entry in human and bovine endothelial cells  Journal Articles
• Predictive Value of Bone Resorption and Formation Markers in Cancer Patients With Bone Metastases Receiving the Bisphosphonate Zoledronic Acid  Conferences
• Predictors of Skeletal Complications in Men with Hormone-Refractory Metastatic Prostate Cancer  Journal Articles
• Proton Pump Inhibitors and Survival Outcomes in Patients With Metastatic Renal Cell Carcinoma  Journal Articles
• REVIEW ARTICLE: The Role of Toll‐Like Receptor Ligands/Agonists in Protection Against Genital HSV‐2 Infection  Journal Articles
• Randomized Phase III Study of Matrix Metalloproteinase Inhibitor BMS-275291 in Combination With Paclitaxel and Carboplatin in Advanced Non-Small-Cell Lung Cancer: National Cancer Institute of Canada-Clinical Trials Group Study BR.18  Journal Articles
• Randomized phase II feasibility study of combining the matrix metalloproteinase inhibitor BMS-275291 with paclitaxel plus carboplatin in advanced non-small cell lung cancer  Journal Articles
• Receptor subtypes mediating spinal cardiovascular effects of angiotensin II in rat using losartan and PD 123319  Journal Articles
• Reduced Tissue Levels of Noradrenaline Are Associated with Behavioral Phenotypes of the TgCRND8 Mouse Model of Alzheimer's Disease  Journal Articles
• Reduction of Nilutamide by NO Synthases:  Implications for the Adverse Effects of This Nitroaromatic Antiandrogen Drug  Journal Articles
• Reorientation phenomena in imidazolium methyl sulfonate as probed by advanced solid-state NMR  Journal Articles
• Robust, anti-biofouling 2D nanogel films from poly(N-vinyl caprolactam-co-vinylimidazole) polymers  Journal Articles
• Role of Bone-Modifying Agents in Metastatic Breast Cancer: An American Society of Clinical Oncology–Cancer Care Ontario Focused Guideline Update  Journal Articles
• Sensitivity of the early-life stages of freshwater mollusks to neonicotinoid and butenolide insecticides  Journal Articles
• Spanish toxic oil syndrome: An isothiocyanate-derived compound cannot be substantiated as a causative agent  Journal Articles
• Spatial structure of the novel light-sensitive photoprotein berovin from the ctenophore Beroe abyssicola in the Ca2+-loaded apoprotein conformation state  Journal Articles
• Stability strengths oncogenic activity  Journal Articles
• Subgroup Variations in Bone Mineral Density Response to Zoledronic Acid After Hip Fracture  Journal Articles
• Superantigen immune stimulation activates epithelial STAT-1 and PI 3-K: PI 3-K regulation of permeability  Journal Articles
• Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines  Journal Articles
• Synthesis, characterization, structure, molecular modeling studies and biological activity of sterically crowded Pt(II) complexes containing bis(imidazole) ligands  Journal Articles
• TGF-β effects on epithelial ion transport and barrier: reduced Cl⁻ secretion blocked by a p38 MAPK inhibitor  Journal Articles
• The HORIZON Recurrent Fracture Trial: design of a clinical trial in the prevention of subsequent fractures after low trauma hip fracture repair  Journal Articles
• The Pharmacokinetics and Pharmacodynamics of Zoledronic Acid in Cancer Patients with Varying Degrees of Renal Function  Conferences
• The Use of Zoledronic Acid, a Novel, Highly Potent Bisphosphonate, for the Treatment of Hypercalcemia of Malignancy  Journal Articles
• The further development of rainbow trout primary epithelial cell cultures as a diagnostic tool in ecotoxicology risk assessment  Journal Articles
• The pharmacodynamics and pharmacokinetics of S‐tenatoprazole‐Na 30 mg, 60 mg and 90 mg vs. esomeprazole 40 mg in healthy male subjects  Journal Articles
• The role of thromboxane in allergen-induced asthmatic responses  Journal Articles
• Time and Labor Costs Associated With Administration of Intravenous Bisphosphonates for Breast or Prostate Cancer Patients With Metastatic Bone Disease: A Time and Motion Study  Journal Articles
• Tolerability of Different Dosing Regimens of Bisphosphonates for the Treatment of Osteoporosis and Malignant Bone Disease  Journal Articles
• Treatment of Hypertension with Clonidine  Journal Articles
• Treatment of advanced cancer of the prostate.  Journal Articles
• Use of Adjuvant Bisphosphonates and Other Bone-Modifying Agents in Breast Cancer: A Cancer Care Ontario and American Society of Clinical Oncology Clinical Practice Guideline  Journal Articles
• Vardenafil Improves Erectile Function in Men with Erectile Dysfunction Irrespective of Disease Severity and Disease Classification  Journal Articles
• Vardenafil Improves Patient Satisfaction with Erection Hardness, Orgasmic Function, and Overall Sexual Experience, While Improving Quality of Life in Men with Erectile Dysfunction  Journal Articles
• Vardenafil and Weaning from Inhaled Nitric Oxide: Effect on Pulmonary Hypertension in ARDS  Journal Articles
• Vasopressin Increases Intracellular NO Concentration via Ca ²⁺ Signaling in Inner Medullary Collecting Duct  Conferences
• Vasopressin increases intracellular NO concentration via Ca(2+) signaling in inner medullary collecting duct.  Journal Articles
• Zoledronate (CGP 42'446), a bisphosphonate, protects against metaphyseal intracortical defects in experimental inflammatory arthritis  Journal Articles
• Zoledronic Acid Is Superior to Pamidronate in the Treatment of Hypercalcemia of Malignancy: A Pooled Analysis of Two Randomized, Controlled Clinical Trials  Journal Articles
• Zoledronic Acid and Survival in Breast Cancer Patients with Bone Metastases and Elevated Markers of Osteoclast Activity  Journal Articles
• Zoledronic Acid and Survival in Patients with Metastatic Bone Disease from Lung Cancer and Elevated Markers of Osteoclast Activity  Journal Articles
• Zoledronic acid and survival in breast cancer patients with bone metastases and elevated markers of osteoclast activity.  Journal Articles
• Zoledronic acid in the treatment of hypercalcemia of malignancy: Results of the international clinical development program  Journal Articles
• Zoledronic acid is superior to pamidronate for the treatment of bone metastases in breast carcinoma patients with at least one osteolytic lesion  Journal Articles
• Zoledronic acid results in better health-related quality of life following hip fracture: the HORIZON–Recurrent Fracture Trial  Journal Articles
• Zoledronic acid use in cancer patients  Journal Articles
• p53: The pivot between cell cycle arrest and senescence  Journal Articles