Cyclooxygenase Inhibitors Concept

subject area of

• A comparison of the therapeutic efficacy and tolerability of etoricoxib and diclofenac in patients with osteoarthritis  Journal Articles
• A human whole blood assay for clinical evaluation of biochemical efficacy of cyclooxygenase inhibitors  Journal Articles
• A randomized trial measuring fecal blood loss after treatment with rofecoxib, ibuprofen, or placebo in healthy subjects  Journal Articles
• A selective inhibitor of cyclooxygenase-2 reverses endotoxin-induced pyretic responses in non-human primates  Journal Articles
• Abnormal prostaglandin E2 production blocks myogenic differentiation in myotonic dystrophy  Journal Articles
• Analysis of Prostaglandin G/H Synthase-2 Inhibition Using Peroxidase-Induced Luminol Luminescence  Journal Articles
• Antiplatelet Drugs  Journal Articles
• Appropriateness of NSAID and Coxib prescribing for patients with osteoarthritis by primary care physicians in Ontario: results from the CANOAR study.  Journal Articles
• Aspirin in the treatment of cardiovascular disease: A review  Journal Articles
• Aspirin resistance: does it exist and is it an important clinical problem?  Journal Articles
• Aspirin-Resistant Thromboxane Biosynthesis and the Risk of Myocardial Infarction, Stroke, or Cardiovascular Death in Patients at High Risk for Cardiovascular Events  Journal Articles
• Association of cyclooxygenase-2 genetic variant with cardiovascular disease  Journal Articles
• Association of renin–angiotensin and endothelial nitric oxide synthase gene polymorphisms with blood pressure progression and incident hypertension: prospective cohort study  Journal Articles
• Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX‐2 inhibitor  Journal Articles
• Cardiovascular Thrombotic Events in Controlled, Clinical Trials of Rofecoxib  Journal Articles
• Cardiovascular safety of rofecoxib (Vioxx): lessons learned and unanswered questions  Journal Articles
• Celecoxib as an adjunct in the treatment of depressive or mixed episodes of bipolar disorder: a double‐blind, randomized, placebo‐controlled study  Journal Articles
• Changes in rates of upper gastrointestinal hemorrhage after the introduction of cyclooxygenase-2 inhibitors in British Columbia and Ontario  Journal Articles
• Clinical effects of early angiotensin-converting enzyme inhibitor treatment for acute myocardial infarction are similar in the presence and absence of aspirin  Journal Articles
• Cobra venom cardiotoxin induces aggregation of washed rat platelets: dual effects of Ca2+.  Journal Articles
• Complementary studies of the gastrointestinal safety of the cyclo‐oxygenase‐2‐selective inhibitor etoricoxib  Journal Articles
• Corticospinal excitability is associated with hypocapnia but not changes in cerebral blood flow  Journal Articles
• Cost-Effectiveness of Pharmaceutical Management for Osteoarthritis Pain  Journal Articles
• Cyclooxygenase Inhibitors and the Antiplatelet Effects of Aspirin  Journal Articles
• Cyclooxygenase-2 (COX-2) in acute myocardial infarction: cellular expression and use of selective COX-2 inhibitor  Conferences
• Cyclooxygenase-2 Inhibitors  Journal Articles
• Differential Effect of a Selective Cyclooxygenase-2 Inhibitor Versus Indomethacin on Renal Blood Flow in Conscious Volume-Depleted Dogs  Journal Articles
• Effect of Prophylactic Indomethacin in Extremely Low Birth Weight Infants Based on the Predicted Risk of Severe Intraventricular Hemorrhage  Journal Articles
• Effect of calcium concentration and inhibitors on the responses of platelets stimulated with collagen: Contrast between human and rabbit platelets  Journal Articles
• Effect of cardiovascular comorbidities and concomitant aspirin use on selection of cyclooxygenase inhibitor among rheumatologists  Journal Articles
• Effect of cyclooxygenase-2 inhibition with rofecoxib on endothelial dysfunction and inflammatory markers in patients with coronary artery disease  Journal Articles
• Effect of indomethacin on allergen-induced asthmatic responses  Journal Articles
• Effect of prostaglandin synthesis inhibitors on spontaneous and endotoxin-induced abortion in mice  Journal Articles
• Effective, selective and specific inhibition of COX-1 may overcome the “aspirin paradox”  Journal Articles
• Effectiveness and safety of treatments used for the management of patent ductus arteriosus (PDA) in preterm infants: a protocol for a systematic review and network meta-analysis  Journal Articles
• Effectiveness and tolerance of anti‐inflammatory drugs' add‐on therapy in major mental disorders: a systematic qualitative review  Journal Articles
• Effects of some naturally occurring prostanoids and some cyclooxygenase inhibitors on the contractility of the human lower uterine segment in vitro  Journal Articles
• Eicosanoid interactions in the canine proximal colon  Journal Articles
• Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2.  Journal Articles
• Evaluation of Health-Related Values and Preferences of Adults Who Were Preterm Infants and Parents of Preterm Infants Concerning Use of Prophylactic Cyclooxygenase Inhibitor Drugs  Journal Articles
• Evidence-Based Recommendations for Short- and Long-Term Management of Uninvestigated Dyspepsia in Primary Care: An Update of the Canadian Dyspepsia Working Group (CanDys) Clinical Management Tool  Journal Articles
• Function of cyclo‐oxygenase‐1 and cyclo‐oxygenase‐2 in the ductus arteriosus from foetal lamb: differential development and change by oxygen and endotoxin  Journal Articles
• Hydrogen peroxide is an endothelium‐dependent contracting factor in rat renal artery  Journal Articles
• Ibuprofen fails to prevent brain pathology in a model of neuropsychiatric lupus.  Journal Articles
• Ibuprofen prophylaxis in preterm neonates  Journal Articles
• Incomplete Inhibition of Thromboxane Biosynthesis by Acetylsalicylic Acid  Journal Articles
• Incremental Cost-Effectiveness Analysis Comparing Rofecoxib with Nonselective NSAIDs in Osteoarthritis  Journal Articles
• Indomethacin prophylaxis, patent ductus arteriosus, and the risk of bronchopulmonary dysplasia: Further analyses from the Trial of Indomethacin Prophylaxis in Preterms (TIPP)  Journal Articles
• Inhibition of COX pathway in experimental myocardial infarction  Journal Articles
• Inhibition of COX pathway in experimental myocardial infarction.  Journal Articles
• Inhibition of Cyclooxygenase-2 Improves Cardiac Function in Myocardial Infarction  Journal Articles
• Involvement of eicosanoids and macrophage-like cells in cytokine-mediated changes in rat myenteric nerves  Journal Articles
• L-745,337: A selective inhibitor of cyclooxygenase-2 elicits antinociception but not gastric ulceration in rats  Journal Articles
• Late Asthmatic Responses  Journal Articles
• Leukotrienes in brain: natural occurrence and induced changes  Journal Articles
• Mechanisms of Aspirin-Intolerant Asthma: Identifying Inflammatory Pathways in the Pathogenesis of Asthma  Journal Articles
• Mediation and modulation by eicosanoids of responses of spinal dorsal horn neurons to glutamate and substance P receptor agonists: results with indomethacin in the rat in vivo  Journal Articles
• Mediators of acute lung injury in endotoxaemia.  Journal Articles
• Motion-Cyclo-oxygenase-2 Selective Nonsteroidal Anti-Inflammatory Drugs are as Safe as Placebo for the Stomach: Arguments for the Motion  Journal Articles
• Myths and facts in the use of anti-inflammatory drugs  Journal Articles
• NSAID-induced cyclooxygenase inhibition differentially depresses long-lasting versus brief synaptically-elicited responses of rat spinal dorsal horn neurons in vivo  Journal Articles
• Perivascular adipose tissue promotes vasoconstriction: the role of superoxide anion  Journal Articles
• Pharmacology of a selective cyclooxygenase-2 inhibitor, L-745,337: a novel nonsteroidal anti-inflammatory agent with an ulcerogenic sparing effect in rat and nonhuman primate stomach.  Journal Articles
• Platelet-Active Drugs  Journal Articles
• Platelet-active drugs : the relationships among dose, effectiveness, and side effects.  Journal Articles
• Platelet-active drugs: the relationships among dose, effectiveness, and side effects.  Journal Articles
• Practical considerations for the use of nonsteroidal anti-inflammatory drugs and cyclo-oxygenase-2 inhibitors in hypertension and kidney disease.  Journal Articles
• Prevention and 18-Month Outcomes of Serious Pulmonary Hemorrhage in Extremely Low Birth Weight Infants: Results From the Trial of Indomethacin Prophylaxis in Preterms  Journal Articles
• Prophylactic cyclo-oxygenase inhibitor drugs for the prevention of morbidity and mortality in extremely preterm infants: a clinical practice guideline incorporating family values and preferences  Journal Articles
• Prophylactic cyclo-oxygenase inhibitor drugs for the prevention of morbidity and mortality in preterm infants: a network meta-analysis  Journal Articles
• Prostaglandin E2 enhances interleukin 8 (IL-8) and IL-6 but inhibits GMCSF production by IL-1 stimulated human synovial fibroblasts in vitro.  Journal Articles
• Prostaglandin modulation of airway inflammation and hyperresponsiveness in mice sensitized without adjuvant  Journal Articles
• Re: Recommendations for the appropriate use of anti-inflammatory drugs in the era of the coxibs: defining the role of the gastroprotective agents.  Journal Articles
• Reasons for resistance to aspirin in cardiovascular disease.  Journal Articles
• Recommendations for the Appropriate Use of Anti-Inflammatory Drugs in the Era of the Coxibs: Defining the Role of Gastroprotective Agents  Journal Articles
• Regional tissue oxygenation in preterm born infants in association with echocardiographically significant patent ductus arteriosus  Journal Articles
• Revisiting the usefulness of thromboxane-A₂modulation in the treatment of bronchoconstriction in asthma  Journal Articles
• Rofecoxib [Vioxx, MK-0966; 4-(4'-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles.  Journal Articles
• Selective Cyclooxygenase-2 Inhibitors as Potential Therapeutic Agents for Inflammatory Diseases  Journal Articles
• Sensitivity of rabbit platelet and aortic cyclooxygenase to inhibition by aspirin  Journal Articles
• Sensitization of enteric reflexes in the rat colon in vitro  Journal Articles
• Sensory and vascular changes in a rat monoarthritis model: prophylactic and therapeutic effects of meloxicam  Journal Articles
• Should Aspirin Be Discontinued Before Coronary Artery Bypass Surgery?  Journal Articles
• The Role of Mast Cells in Intestinal Immunophysiology  Journal Articles
• The discovery of rofecoxib, [MK 966, VIOXX®, 4-(4′-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2 inhibitor  Journal Articles
• The gastrointestinal safety of the COX-2 selective inhibitor etoricoxib assessed by both endoscopy and analysis of upper gastrointestinal events  Journal Articles
• Thromboxane Prostanoid Receptor Activation Amplifies Airway Stretch-Activated Contractions Assessed in Perfused Intact Bovine Bronchial Segments  Journal Articles