Motion‐Cyclo‐oxygenase‐2 Selective Nonsteroidal Anti‐Inflammatory Drugs are as Safe as Placebo for the Stomach: Arguments for the Motion

Traditional nonsteroidal anti-inflammatory drugs (NSAIDs) are known to cause gastritis, gastric and duodenal ulcers, and gastrointestinal (GI) blood loss, as well as alterations in small bowel permeability. Patients at a high risk for these complications include those who are older than 60 years of age, those with a previous history of complicated peptic disease and bleeding, and those who take high dose or multiple NSAIDs, including low dose …