Journal article
Indomethacin prophylaxis, patent ductus arteriosus, and the risk of bronchopulmonary dysplasia: Further analyses from the Trial of Indomethacin Prophylaxis in Preterms (TIPP)
Abstract
OBJECTIVES: To determine the risk of bronchopulmonary dysplasia (BPD) in subgroups of infants with and without patent ductus arteriosus (PDA) who were randomized to indomethacin prophylaxis or placebo, and to examine whether adverse drug effects on edema formation and oxygenation may explain why indomethacin prophylaxis does not reduce BPD.
STUDY DESIGN: We studied 999 extremely low birth weight infants who participated in the Trial of …
Authors
Schmidt B; Roberts RS; Fanaroff A; Davis P; Kirpalani HM; Nwaesei C; Vincer M; Investigators T
Journal
The Journal of Pediatrics, Vol. 148, No. 6, pp. 730–734.e1
Publisher
Elsevier
Publication Date
6 2006
DOI
10.1016/j.jpeds.2006.01.047
ISSN
0022-3476