Journal article
Leukotrienes in brain: natural occurrence and induced changes
Abstract
Peptidoleukotrienes (SP-LTs) (both total product and individual LTC4 and LTE4 and LTB4 were measured by radioimmunoassay in cerebrospinal fluid (CSF) collected from the third ventricle of conscious cats. Total SP-LT was expressed as LTE4 after treating samples with crude gamma-glutamyltranspeptidase. Prostaglandin (PG) E2 and thromboxane (TX) B2, the stable metabolite of TXA2, were also assayed in part of the experiments. Under basal …
Authors
Hynes N; Bishai I; Lees J; Coceani F
Journal
Brain Research, Vol. 553, No. 1, pp. 4–13
Publisher
Elsevier
Publication Date
7 1991
DOI
10.1016/0006-8993(91)90222-h
ISSN
0006-8993
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Administration, OralAnimalsArachidonic AcidBody TemperatureBrain ChemistryCatsCerebrospinal FluidCerebrospinal Fluid ProteinsCyclooxygenase InhibitorsDinoprostoneFemaleIn Vitro TechniquesInjections, IntraventricularLeukotrienesLipoxygenase InhibitorsMalePlatelet Activating FactorPyrogensRadioimmunoassayThromboxane B2