selected scholarly activity
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conferences
- Cytomegalovirus infection in steroid-refractory ulcerative colitis. American Journal of Gastroenterology. S257-S257. 2002
- Lack of female urinary inhibitors to Chlamydia trachomatis nucleic acid amplification in the Gen-Probe APTIMA Combo 2 assay. Clinical Infectious Diseases. 1247-1247. 2001
- Vascular invasion and persistent Chlamydia pneumoniae infection in mucosa-associated lymphoid tissue in a rabbit model. The FASEB Journal. A937-A937. 2001
- A rabbit model for disseminated Mycoplasma pneumoniae infection.. Modern Pathology. 144A-144A. 1998
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journal articles
- Enumeration of Viable Chlamydia from Infected Animals Using Immunofluorescent Microscopy. Methods in molecular biology (Clifton, N.J.). 2042:237-244. 2019
- Electrical Tweezer for Droplet Transportation, Extraction, Merging and DNA Analysis. Micromachines. 8:353-353. 2017
- Hospital admissions for lower respiratory tract infections among infants in the Canadian Arctic: a cohort study. CMAJ open. 4:E615-E622. 2016
- Immunization with chlamydial type III secretion antigens reduces vaginal shedding and prevents fallopian tube pathology following live C. muridarum challenge. Vaccine. 34:3979-3985. 2016
- Chlamydia Outer Protein (Cop) B from Chlamydia pneumoniae possesses characteristic features of a type III secretion (T3S) translocator protein. BMC Microbiology. 15:163. 2015
- Targeting PI3K-p110α Suppresses Influenza Virus Infection in Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. 191:1012-1023. 2015
- Chlamydia pneumoniae CopD Translocator Protein Plays a Critical Role in Type III Secretion (T3S) and Infection. PLoS ONE. 9:e99315-e99315. 2014
- Multiplex loop-mediated isothermal amplification (M-LAMP) assay for the detection of influenza A/H1, A/H3 and influenza B can provide a specimen-to-result diagnosis in 40min with single genome copy sensitivity. Journal of Clinical Virology. 58:127-131. 2013
- Development of a Sensitive Loop-Mediated Isothermal Amplification Assay That Provides Specimen-to-Result Diagnosis of Respiratory Syncytial Virus Infection in 30 Minutes. Journal of Clinical Microbiology. 51:2696-2701. 2013
- Structural Characterization of a Novel Chlamydia pneumoniae Type III Secretion-Associated Protein, Cpn0803. PLoS ONE. 7:e30220-e30220. 2012
- Molecular diagnosis of respiratory virus infections. Critical Reviews in Clinical Laboratory Sciences. 48:217-249. 2011
- Prognosis of West Nile virus associated acute flaccid paralysis: a case series. Journal of Medical Case Reports. 5:395. 2011
- Evaluation and Clinical Validation of an Alcohol-Based Transport Medium for Preservation and Inactivation of Respiratory Viruses. Journal of Clinical Microbiology. 49:2138-2142. 2011
- Expectant management versus immediate treatment for low‐grade cervical intraepithelial neoplasia. Cancer. 117:1438-1445. 2011
- Chlamydia Pneumoniae CdsL Regulates CdsN ATPase Activity, and Disruption with a Peptide Mimetic Prevents Bacterial Invasion. Frontiers in Microbiology. 2:21. 2011
- Development of a novel bead-based multiplex PCR assay for combined subtyping and oseltamivir resistance genotyping (H275Y) of seasonal and pandemic H1N1 influenza A viruses. Journal of Clinical Virology. 49:277-282. 2010
- Interactions between flagellar and type III secretion proteins in Chlamydia pneumoniae. BMC Microbiology. 10:18. 2010
- Nucleic acid amplification-based diagnosis of respiratory virus infections. Expert Review of Anti-Infective Therapy. 8:1273-1292. 2010
- Development and Evaluation of a Flocked Nasal Midturbinate Swab for Self-Collection in Respiratory Virus Infection Diagnostic Testing. Journal of Clinical Microbiology. 48:3340-3342. 2010
- The role of cytology (Pap tests) and human papillomavirus testing in anal cancer screening. AIDS. 24:1307-1313. 2010
- A novel inhibitor of Chlamydophila pneumoniae protein kinase D (PknD) inhibits phosphorylation of CdsD and suppresses bacterial replication. BMC Microbiology. 9:218. 2009
- Difficulty with mumps diagnosis: What is the contribution of mumps mimickers?. Journal of Clinical Virology. 46:381-383. 2009
- Cost Analysis of Multiplex PCR Testing for Diagnosing Respiratory Virus Infections. Journal of Clinical Microbiology. 47:2812-2817. 2009
- Risk Factors and Viruses Associated With Hospitalization Due to Lower Respiratory Tract Infections in Canadian Inuit Children. Pediatric Infectious Disease Journal. 28:697-701. 2009
- Multiplex PCR tests sentinel the appearance of pandemic influenza viruses including H1N1 swine influenza. Journal of Clinical Virology. 45:200-202. 2009
- Characterization of the Putative Type III Secretion ATPase CdsN (Cpn0707) ofChlamydophila pneumoniae. Journal of Bacteriology. 190:6580-6588. 2008
- Detection of Respiratory Viruses by Molecular Methods. Clinical Microbiology Reviews. 21:716-747. 2008
- Asthma Management by Monitoring Sputum Neutrophil Count. Chest. 134:628-630. 2008
- Interactions between CdsD, CdsQ, and CdsL, Three PutativeChlamydophila pneumoniaeType III Secretion Proteins. Journal of Bacteriology. 190:2972-2980. 2008
- Chlamydophila pneumoniae PknD Exhibits Dual Amino Acid Specificity and Phosphorylates Cpn0712, a Putative Type III Secretion YscD Homolog. Journal of Bacteriology. 189:7549-7555. 2007
- Issues for reporting results. Journal of Clinical Virology. 40:S47-S50. 2007
- The clinical need for the RVP test. Journal of Clinical Virology. 40:S36-S38. 2007
- The pathogens. Journal of Clinical Virology. 40:S5-S10. 2007
- Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus. Journal of General Virology. 87:641-650. 2006
- Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus. Journal of General Virology. 87:641-650. 2006
- Molecular Diagnosis of Severe Acute Respiratory Syndrome. Journal of Molecular Diagnostics. 7:551-559. 2005
- Interobserver agreement in the interpretation of anal intraepithelial neoplasia. Cancer. 103:1447-1456. 2005
- Combining Human Papillomavirus Testing or Cervicography With Cytology to Detect Cervical Neoplasia. Archives of Pathology and Laboratory Medicine. 128:1257-1262. 2004
- Performance and Cost Evaluation of One Commercial andSix In-House Conventional and Real-Time ReverseTranscription-PCR Assays for Detection of Severe AcuteRespiratory SyndromeCoronavirus. Journal of Clinical Microbiology. 42:1471-1476. 2004
- Adjunctive Human Papillomavirus Testing in the 2-Year Follow-up of Women With Low-Grade Cervical Cytologic Abnormalities: A Randomized Trial and Economic Evaluation. Archives of Pathology and Laboratory Medicine. 127:1169-1175. 2003
- Incidence, clearance and predictors of human papillomavirus infection in women.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 168:421-425. 2003
- Chlamydiae Host Cell Interactions Revealed Using DNA Microarrays. Annals of the New York Academy of Sciences. 975:192-201. 2002
- Smoking, season, and detection of chlamydia pneumoniaeDNA in clinically stable COPD patients. BMC Infectious Diseases. 2:12. 2002
- Prevalence of infection with carcinogenic human papillomavirus among older women.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 167:871-873. 2002
- Strategic Targeting of Essential Host-pathogen Interactions in Chlamydial Disease. Infectious Disorders - Drug Targets. 2:201-216. 2002
- Influence of Clarithromycin on Early Atherosclerotic Lesions after Chlamydia pneumoniae Infection in a Rabbit Model. Antimicrobial Agents and Chemotherapy. 46:2321-2326. 2002
- Identification of MEK- and phosphoinositide 3-kinase-dependent signalling as essential events during Chlamydia pneumoniae invasion of HEp2 cells. Cellular Microbiology. 4:447-460. 2002
- Chlamydia pneumoniaeInfection of Endothelial Cells Induces Transcriptional Activation of Platelet‐Derived Growth Factor–B: A Potential Link to Intimal Thickening in a Rabbit Model of Atherosclerosis. Journal of Infectious Diseases. 185:1621-1630. 2002
- Effect of routine use of a multiplex PCR for detection of vanA- and vanB- mediated enterococcal resistance on accuracy, costs and earlier reporting. Diagnostic Microbiology and Infectious Disease. 41:215-220. 2001
- Randomised, blinded, placebo controlled trial of doxycycline for chronic seronegative arthritis. Annals of the Rheumatic Diseases. 60:1088-1094. 2001
- Dendritic cell discoveries provide new insight into the cellular immunobiology of DNA vaccines. Immunology Letters. 78:103-111. 2001
- Replicate PCR Testing and Probit Analysis for Detection and Quantitation of Chlamydia pneumoniae in Clinical Specimens. Journal of Clinical Microbiology. 39:1796-1801. 2001
- Chlamydia pneumoniae and atherosclerosis: does the evidence support a causal or contributory role?. FEMS Microbiology Letters. 197:1-9. 2001
- Evaluation of the NucliSens Basic Kit for Detection of Chlamydia trachomatis and Neisseria gonorrhoeae in Genital Tract Specimens Using Nucleic Acid Sequence-Based Amplification of 16S rRNA. Journal of Clinical Microbiology. 39:1429-1435. 2001
- Previous exposure to Chlamydia pneumoniae, Helicobacter pylori and other infections in Canadian patients with ischemic heart disease.. Canadian Journal of Cardiology. 17:270-276. 2001
- cDNA Array Analysis of Altered Gene Expression in Human Endothelial Cells in Response toChlamydia pneumoniaeInfection. Infection and Immunity. 69:1420-1427. 2001
- Circulating Nucleic Acids of Chlamydia pneumoniae and Cytomegalovirus in Patients Undergoing Coronary Angiography. Journal of Clinical Microbiology. 39:596-600. 2001
- Comparison of human papillomavirus DNA testing and repeat Papanicolaou test in women with low-grade cervical cytologic abnormalities: a randomized trial. CANADIAN MEDICAL ASSOCIATION JOURNAL. 163:701-707. 2000
- Comparison of human papillomavirus DNA testing and repeat Papanicolaou test in women with low-grade cervical cytologic abnormalities: a randomized trial. HPV Effectiveness in Lowgrade Paps (HELP) Study No. 1 Group.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 163:701-707. 2000
- Comparison of self-collected vaginal, vulvar and urine samples with physician-collected cervical samples for human papillomavirus testing to detect high-grade squamous intraepithelial lesions.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 163:513-518. 2000
- Prevalence and predictors of human papillomavirus infection in women in Ontario, Canada. CANADIAN MEDICAL ASSOCIATION JOURNAL. 163:503-508. 2000
- Prevalence and predictors of human papillomavirus infection in women in Ontario, Canada. Survey of HPV in Ontario Women (SHOW) Group.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 163:503-508. 2000
- Nucleic Acid Sequence Based Amplification (NASBA) of Chlamydia pneumoniae Major Outer Membrane Protein (ompA) mRNA with Bioluminescent Detection. Combinatorial Chemistry and High Throughput Screening. 3:315-327. 2000
- Quantitation of Chlamydia trachomatis 16S rRNA Using NASBA Amplification and a Bioluminescent Microtiter Plate Assay. Combinatorial Chemistry and High Throughput Screening. 3:303-313. 2000
- Analytical Sensitivity, Reproducibility of Results, and Clinical Performance of Five PCR Assays for Detecting Chlamydia pneumoniae DNA in Peripheral Blood Mononuclear Cells. Journal of Clinical Microbiology. 38:2622-2627. 2000
- The role of Chlamydia pneumoniae in atherosclerosis – recent evidence from animal models: Response. Trends in Microbiology. 8:257-257. 2000
- Generation of reactive oxygen species and formation of membrane lipid peroxides in cells infected with Chlamydia trachomatis. International Journal of Infectious Diseases. 4:46-50. 2000
- Can an Antibiotic (Macrolide) Prevent Chlamydia pneumoniae -Induced Atherosclerosis in a Rabbit Model?. Clinical and Vaccine Immunology. 6:891-894. 1999
- De Novo Induction of Atherosclerosis by Chlamydia pneumoniae in a Rabbit Model. Infection and Immunity. 67:6048-6055. 1999
- Direct detection of vanA and vanB genes in clinical specimens for rapid identification of vancomycin resistant enterococci (VRE) using multiplex PCR. Molecular and Cellular Probes. 13:275-281. 1999
- Chlamydia pneumoniae Infection of Human Endothelial Cells Induces Proliferation of Smooth Muscle Cells via an Endothelial Cell-Derived Soluble Factor(s). Infection and Immunity. 67:2909-2915. 1999
- Molecular Diagnosis of Chlamydia trachomatis Infections by Probe Hybridization, PCR, LCR, TMA, and Q-β Replicase. Methods in Molecular Medicine. 20:33-46. 1999
- Evaluation of clinical algorithms for the diagnosis of gonococcal and chlamydial infections among men with urethral discharge or dysuria and women with vaginal discharge in Benin (vol 74, pg S44, 1998). Sexually Transmitted Infections. 74:459-459. 1998
- Economic Evaluation of Hybrid Capture Human Papillomavirus Testing in Women with Low-Grade Papanicolaou Smear Abnormalities. Journal of Lower Genital Tract Disease. 2:213-220. 1998
- Predictors of positivity for hepatitis B and the derivation of a selective screening rule in a Canadian sexually transmitted diseases clinic1Presented in part at the 10th meeting of the International Society for Sexually Transmitted Diseases Research, Helsinki, Finland, August 29–September 1, 1993 and the 61st Meeting of the Canadian Association of Clinical Microbiology and Infectious Diseases, November 21–25, 1993, Vancouver, BC.1. Journal of Clinical Virology. 11:85-91. 1998
- Evaluation of clinical algorithms for the diagnosis of gonococcal and chlamydial infections among men with urethral discharge or dysuria and women with vaginal discharge in Benin.. Sexually Transmitted Infections. 74 Suppl 1:S44-S49. 1998
- Interaction between Chlamydia trachomatis and cellular components of the immune system. Medical Science Research. 26:115-118. 1998
- Markers of inflammation in induced sputum in acute bronchitis caused by Chlamydia pneumoniae.. Thorax. 52:929-931. 1997
- Detection of Chlamydia trachomatis, Neisseria gonorrhoeae, Ureaplasma urealyticum, and Mycoplasma genitalium in First-void Urine Specimens by Multiplex Polymerase Chain Reaction.. Molecular Diagnosis and Therapy. 2:161-168. 1997
- Detection of Chlamydia trachomatis, Neisseria gonorrhoeae, Ureaplasma urealyticum, and Mycoplasma genitalium in first-void urine specimens by multiplex polymerase chain reaction. Molecular Diagnosis and Therapy. 2:161-168. 1997
- Urinary inhibitors of polymerase chain reaction and ligase chain reaction and testing of multiple specimens may contribute to lower assay sensitivities for diagnosingChlamydia trachomatisinfected women. Molecular and Cellular Probes. 11:243-249. 1997
- Understanding and enhancing compliance with the second dose of hepatitis B vaccine: a cohort analysis and a randomized controlled trial.. CANADIAN MEDICAL ASSOCIATION JOURNAL. 157:143-148. 1997
- Ability of commercial ligase chain reaction and PCR assays to diagnose Chlamydia trachomatis infections in men by testing first-void urine. Journal of Clinical Microbiology. 35:982-984. 1997
- HIV infection in female prostitutes from Benin: association with symptomatic but not asymptomatic gonococcal or chlamydial infections.. AIDS. 11:685-686. 1997
- Evaluation of a Screening Algorithm for the Diagnosis of Genital Infections With Neisseria gonorrhoeae and Chlamydia trachomatis Among Female Sex Workers in Bénin. Sexually Transmitted Diseases. 24:109-115. 1997
- Multiplex Polymerase Chain Reaction for the Diagnosis of Sexually Transmitted Diseases. Clinics in Laboratory Medicine. 16:61-71. 1996
- Multiplex PCR for detection of Chlamydia trachomatis and Neisseria gonorrhoeae in Genitourinary specimens. Journal of Clinical Microbiology. 33:3049-3053. 1995
- Lack of Specificity of HTLV Antibody Enzyme Immunoassays. Journal of Acquired Immune Deficiency Syndromes (1999). 9:523???524-523???524. 1995
- Diagnostic value of detecting JC virus DNA in cerebrospinal fluid of patients with progressive multifocal leukoencephalopathy. Journal of Clinical Microbiology. 33:484-486. 1995
- Immunology: Chlamydial immunoglobulin IgG and IgA antibodies in serum and semen are not associated with the presence of Chlamydia trachomatis DNA or rRNA in semen from male partners of infertile couples. Human Reproduction. 10:315-319. 1995
- Detection of Chlamydia trachomatis Antigens in Male Urethral Swabs and Urines With a Microparticle Enzyme Immunoassay. Sexually Transmitted Diseases. 22:55-59. 1995
- Diagnosis of Chlamydia trachomatis infections in men and women by testing first-void urine by ligase chain reaction. Journal of Clinical Microbiology. 32:2682-2685. 1994
- Role of confirmatory PCRs in determining performance of Chlamydia Amplicor PCR with endocervical specimens from women with a low prevalence of infection. Journal of Clinical Microbiology. 32:2490-2493. 1994
- Leukocyte esterase urine strips for the screening of men with urethritis--use in developing countries.. Sexually Transmitted Infections. 70:3-6. 1994
- Interlaboratory agreement study of a double set of PCR plasmid primers for detection of Chlamydia trachomatis in a variety of genitourinary specimens. Journal of Clinical Microbiology. 32:87-91. 1994
- Comparison of plasmid- and chromosome-based polymerase chain reaction assays for detecting Chlamydia trachomatis nucleic acids. Journal of Clinical Microbiology. 31:1753-1758. 1993
- Progressive multifocial leukoencephalopathy in a child with immunodeficiency and hyperimmunoglobulinemia M. Pediatric Infectious Disease Journal. 12:399-401. 1993
- Screening Urine with a Leukocyte Esterase Strip and Subsequent Chlamydial Testing of Asymptomatic Men Attending Primary Care Practitioners. Sexually Transmitted Diseases. 20:152-157. 1993
- Vertical Transmission of Viral Hepatitis. Transfusion Medicine Reviews. 7:112-120. 1993
- Effects of Broadening the Gold Standard on the Performance of a Chemiluminometric Immunoassay to Detect Chlamydia trachomatis Antigens in Centrifuged First Void Urine and Urethral Swab Samples from Men. Sexually Transmitted Diseases. 19:315-319. 1992
- Chlamydia trachomatis confirmatory testing of PCR-positive genitourinary specimens using a second set of plasmid primers. Molecular and Cellular Probes. 6:381-388. 1992
- Confirmatory polymerase chain reaction testing for Chlamydia trachomatis in first-void urine from asymptomatic and symptomatic men. Journal of Clinical Microbiology. 30:2241-2245. 1992
- Effectiveness and efficiency of selective vs universal screening for chlamydial infection in sexually active young women. JAMA Internal Medicine. 152:1837-1844. 1992
- Ciliary Function, Cell Viability, and in Vitro Effect of Ribavirin on Nasal Epithelial Cells in Acute Rhinorrhea. Chest. 102:284-287. 1992
- The effects of equine rhinovirus, influenza virus and herpesvirus infection on tracheal clearance rate in horses.. Canadian Journal of Veterinary Research. 56:115-121. 1992
- Chlamydial antibodies in children with lower respiratory disease. Pediatric Infectious Disease Journal. 11:68-71. 1992
- Replication and cytopathaology of human parvovirus B19 in human umbilical cord blood erythroid progenitor cells. Journal of Medical Virology. 36:125-130. 1992
- Nasal polyposis: in search of a viral etiology using DNA hybridization.. Journal of Otolaryngology - Head and Neck Surgery. 20:404-407. 1991
- The diagnosis of acute viral hepatitis A or B by microparticle enzyme immunoassay. Journal of Virological Methods. 34:291-296. 1991
- Analysis of a pregnancy‐screening and neonatal‐immunization program for hepatitis B in Hamilton, Ontario, Canada, 1977‐1988. Journal of Medical Virology. 35:50-54. 1991
- Comparison of Cervical, Urethral, and Urine Specimens for the Detection of Chlamydia trachomatis in Women. Journal of Infectious Diseases. 164:205-208. 1991
- Negative staining in the detection of viruses in clinical specimens. Micron. 22:449-460. 1991
- A new immune complex dot assay for detection of rotavirus antigen in faeces. Journal of Virological Methods. 29:157-166. 1990
- Sensitive solid-phase immune electron microscopy double-antibody technique with gold-immunoglobulin G complexes for detecting rotavirus in cell culture and feces. Journal of Clinical Microbiology. 28:864-868. 1990
- Role of Ureaplasma urealyticum and other pathogens in the development of chronic lung disease of prematurity.. Pediatric Infectious Disease Journal. 7:547-551. 1988
- Value of the Gram-Stained Urethral Smear in the Management of Men with Urethritis. Sexually Transmitted Diseases. 15:78-84. 1988
- Tubal factor infertility: an association with prior chlamydial infection and asymptomatic salpingitis. Fertility and Sterility. 49:451-457. 1988
- Chlamydial pneumonia in Costa Rica: results of a case-control study.. Bulletin of the World Health Organization. 66:365-368. 1988
- Combined testing for antibodies to rubella non-structural and envelope proteins sentinels infections in two outbreaks. Diagnostic Microbiology and Infectious Disease. 8:173-177. 1987
- Cost and performance analysis of haemagglutination inhibition, passive haemagglutination, radial haemolysis, and enzyme immunoassay for measuring rubella antibody. Journal of Virological Methods. 18:133-142. 1987
- Detection of chlamydial inclusions in cell culture or biopsy tissue by alkaline phosphatase-anti-alkaline phosphatase staining. Journal of Clinical Microbiology. 25:1864-1867. 1987
- Accuracy of immunoglobulin M immunoassay for diagnosis of chlamydial infections in infants and adults. Journal of Clinical Microbiology. 24:731-735. 1986
- Seroconversion After Hepatitis B Vaccination. ACP journal club. 105:293-293. 1986
- Detection of Chlamydia trachomatis Antigens by Enzyme Immunoassay and Immunofluorescence in Genital Specimens from Symptomatic and Asymptomatic Men and Women. Journal of Infectious Diseases. 154:141-148. 1986
- Differences in antibody responses with rapid agglutination tests for the detection of rubella antibodies. Journal of Clinical Microbiology. 23:772-776. 1986
- Effect of swab type and storage temperature on the isolation of Chlamydia trachomatis from clinical specimens. Journal of Clinical Microbiology. 22:865-867. 1985
- Clinical evaluation of the sensitivity and specificity of a commercially available enzyme immunoassay for detection of rubella virus-specific immunoglobulin M. Journal of Clinical Microbiology. 20:400-404. 1984
- Identification and typing of herpes simplex virus by enzyme immunoassay with monoclonal antibodies. Journal of Clinical Microbiology. 20:162-166. 1984
- Detection of viral antigens, particles, and early antibodies in diagnosis.. Yale Journal of Biology and Medicine. 57:757-776. 1984
- Measurement of BK papovavirus IgG and IgM by radioimmunoassay (RIA). Journal of Medical Virology. 14:101-114. 1984
- Detection of Antichlamydial Immunoglobulin G and M Antibodies by Enzyme-Linked Immunosorbent Assay. Journal of Clinical Microbiology. 18:270-275. 1983
- The Structural Conservation of S100 Protein During Evolution: Analysis by Reactivity with a Monoclonal Antibody. Journal of Neurochemistry. 41:107-112. 1983
- Analysis of Messenger RNA Coding for S100 Protein in the Mammalian Brain. Journal of Neurochemistry. 35:823-828. 1980
- Fate of mRNA following disaggregation of brain polysomes after administration of (+)-lysergic acid diethylamide in vivo. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 565:161-172. 1979