Journal article
Replication and cytopathaology of human parvovirus B19 in human umbilical cord blood erythroid progenitor cells
Abstract
Human parvovirus B19 productively infected erythroid progenitor (EP) cells from umbilical cord blood, in vitro as shown by an increase of viral DNA in supernatant fluid assayed by dot blot hybridization and liquid scintillation counting. Progeny virus was released into the supernatant fluid of CD34+ EP cells which had been purified by immunomagnetic separation. This supernatant fluid was infectious for bone marrow cells. Erythroid bursts …
Authors
Sosa CE; Mahony JB; Luinstra KE; Sternbach M; Chernesky MA
Journal
Journal of Medical Virology, Vol. 36, No. 2, pp. 125–130
Publisher
Wiley
Publication Date
February 1992
DOI
10.1002/jmv.1890360209
ISSN
0146-6615