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Quantitation of Chlamydia trachomatis 16S rRNA...
Journal article

Quantitation of Chlamydia trachomatis 16S rRNA using NASBA amplification and a bioluminescent microtiter plate assay.

Abstract

We developed a nucleic acid sequence based amplification (NASBA) assay which employs the recombinant photoprotein Aequorin in a microtiter plate format for detection and quantitation of C. trachomatis that may be useful in large scale epidemiological studies aimed at improving our understanding of factors affecting transmission of this sexually transmitted pathogen. The conditions for NASBA amplification of the16S rRNA target were optimized (90 …

Authors

Song X; Coombes BK; Mahony JB

Journal

Combinatorial Chemistry & High Throughput Screening, Vol. 3, No. 4, pp. 303–313

Publisher

Bentham Science Publishers

Publication Date

August 2000

DOI

10.2174/1386207003331571

ISSN

1386-2073