Journal article
Development of a novel bead-based multiplex PCR assay for combined subtyping and oseltamivir resistance genotyping (H275Y) of seasonal and pandemic H1N1 influenza A viruses
Abstract
BACKGROUND: The identification of influenza A virus subtypes in clinical specimens is becoming increasingly important for clinical laboratories since seasonal H1N1, H3N2 and pandemic H1N1 influenza A viruses can have defined antiviral resistance patterns and subtyping can be used as a surrogate for antiviral resistance testing.
OBJECTIVES: To develop a novel multiplex PCR (M-PCR) assay for the combined identification of influenza A subtype and …
Authors
Mahony JB; Chong S; Luinstra K; Petrich A; Smieja M
Journal
Journal of Clinical Virology, Vol. 49, No. 4, pp. 277–282
Publisher
Elsevier
Publication Date
December 2010
DOI
10.1016/j.jcv.2010.08.006
ISSN
1386-6532