selected scholarly activity
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books
- Medical Imaging 2013
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chapters
- Multimodality Imaging with MR/PET and MR/SPECT. 359-402. 2017
- Methods and applications of dynamic SPECT imaging. 285-319. 2017
- Physics of PET and SPECT Imaging. 285-320. 2017
- Multimodality imaging with MR/PET and MR/SPECT. 359-402. 2013
- Multimodality Imaging with MR/PET and MR/SPECT. 315-358. 2010
- Attenuation, Scatter, and Spatial Resolution Compensation in SPECT. 473-498. 2004
- Chapter 22 Attenuation, Scatter, and Spatial Resolution Compensation in SPECT. 473-498. 2004
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conferences
- Ventilation Defect Burden Quantified by Technegas SPECT and 129Xe MRI Predicts Lung Cancer Resection Outcomes. C29. ADVANCED LUNG IMAGING; THE PULMONARY PAPARAZZI. a5227-a5227. 2024
- VQ-SPECT/CT Following Recovery From Non-critical COVID-19: 6 Month Longitudinal Follow-up. American Journal of Respiratory and Critical Care Medicine. 2023
- NUTRITIONAL STATUS OF GUATEMALAN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) AND THEIR SIBLINGS. A STUDY OF THE RELATIVE IMPACTS OF DISEASE AND SOCIO-ECONOMIC STATUS (SES). Pediatric Blood and Cancer. S575-S575. 2022
- SAFETY AND EFFICACY OF ALENDRONATE TO TREAT OSTEOPENIA IN CHILDREN DURING THERAPY FOR ACUTE LYMPHOBLASTIC LEUKEMIA. Pediatric Blood and Cancer. 2022
- Prevalence and Clinical Relevance of Ventilation Heterogeneity and Luminal Cellular Inflammation in Lung Cancer Patients Prior to Lung Resection: An Interim Analysis. American Journal of Respiratory and Critical Care Medicine. 2022
- Ventilation and Perfusion Abnormalities Following Recovery from Non-Critical COVID-19. C30. LIFE AND LUNGS AFTER COVID: FUNCTIONAL RECOVERY AND OUTCOMES FOLLOWING SARS-CoV2 INFECTION. a3920-a3920. 2022
- Bone health in long-term survivors of pediatric acute lymphoblastic leukemia. An assessment by peripheral quantitative computed tomography. Pediatric Blood and Cancer. 2021
- Bone Health in Long-Term Survivors of Acute Lymphoblastic Leukemia (ALL) Addressed by Peripheral Quantitative Computed Tomography (PQCT). Pediatric Blood and Cancer. S189-S190. 2021
- Body Composition of Children With Acute Lymphoblastic Leukemia (ALL) in Guatemala. An Assessment by Dual Energy X Ray Absorptiometry (DXA). Pediatric Blood and Cancer. S258-S258. 2020
- Optimizing the SPECT Imaging Workflow For Individualized Dosimetry in Lu177-DOTATATE Treatment Of Progressive Metastatic Neoendocrine Tumors. International Journal of Radiation Oncology Biology Physics. e588-e589. 2020
- Measurement of MR Gradient Effects in CZT Detectors Used in a SPECT/MRI System. 2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC). 1-6. 2020
- Monte Carlo Simulation of Diverging Collimator Geometries for Ring SPECT/MR. 2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC). 1-5. 2020
- 70 Quantifying Tumour Dose Using Individualized Dosimetry Methodology in 177LU Dotatate Therapy. Radiotherapy and Oncology. S32-S32. 2019
- QUANTIFYING TUMOUR DOSE USING INDIVIDUALIZED DOSIMETRY METHODOLOGY IN 177LU DOTATATE THERAPY. Radiotherapy and Oncology. S32-S32. 2019
- Quantifying Renal And Tumor Doses with Individualized Dosimetry In 177Lu DOTATATE Therapy – What Difference Does It Make?. International Journal of Radiation Oncology Biology Physics. S205-S205. 2019
- Sarcopenic Obesity in Long Term Survivors of Acute Lymphoblastic Leukemia (ALL). Pediatric Blood and Cancer. S421-S422. 2017
- Measuring the Mutual Effects of a CZT Detector and a 3T MRI for the Development of a Simultaneous MBI/MRI Insert. IEEE Transactions on Nuclear Science. 2558-2566. 2016
- Measuring the effect of CZT detector materials on MRI field homogeneity. 2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC). 2014
- Validation of convolution based forced detection SIMIND with analytical collimator response modeling using GATE. 2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC). 2014
- 4D Reconstruction of dynamic studies performed using Discovery NM 530c. Journal of Nuclear Medicine. 2014
- A mathematical formulation of the single-pinhole transform and asymptotic properties in fourier space. IEEE Nuclear Science Symposium Conference Record. 2493-2496. 2012
- Accelerated Monte Carlo based simultaneous <sup>99m</sup>Tc/<sup>123</sup>I SPECT reconstruction. IEEE Nuclear Science Symposium Conference Record. 3337-3343. 2012
- Investigating the effect of incorporating backscatter photons in molecular breast imaging. IEEE Nuclear Science Symposium Conference Record. 3049-3053. 2012
- Obtaining patient-specific dose estimates in nuclear medicine studies. IEEE Nuclear Science Symposium Conference Record. 2559-2563. 2012
- Modelling Particle Deposition And Bronchoconstriction In A Rodent Lung Model. A108. AIRWAYS HYPERRESPONSIVENESS: CAUSES AND TREATMENTS. a2426-a2426. 2012
- Investigating silicon photomultipliers for use in a gamma camera. IEEE Nuclear Science Symposium Conference Record. 3372-3377. 2011
- Simultaneous <sup>99m</sup>Tc/<sup>111</sup>In SPECT image reconstruction using convolution based forced detection. IEEE Nuclear Science Symposium Conference Record. 2625-2631. 2011
- Survival of non-small cell lung cancer (NSCLC) patients in a randomized trial as predicted by the FDG-PET standardized uptake value (SUV).. Journal of Clinical Oncology. 7076-7076. 2010
- D- and L-enantiomers of 2-and 6-FDOPA for melanoma imaging. Journal of Nuclear Medicine. 2009
- PET imaging standards for the Ontario Provincial Registry of Cardiac Viability Imaging with FDG PET (CADRE). Journal of Nuclear Medicine. 2009
- Creation of a Pulmonary Model To Aid in Small Animal Imaging.. American Journal of Respiratory and Critical Care Medicine. 2009
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Reactivity and Selectivity of F2 Toward 3,4,6-Tri-O-acetyl-
D -Glucal in Anhydrous HF: Synthesis of [18F]2-Fluoro-2-deoxy-β-D -allose and Its Use for the Detection of a Breast Tumor. ACS Symposium Series. 211-235. 2009 - A low cost data acquisition system for small field of view gamma cameras. IEEE Nuclear Science Symposium Conference Record. 2906-+. 2007
- Collimator-detector response compensation in quantitative SPECT reconstruction. IEEE Nuclear Science Symposium Conference Record. 3955-+. 2007
- FLUO 19-Reactivity and selectivity of F2 towards 3,4,6-tri-O-acetyl-D-glucal in anhydrous HF: Synthesis of [18F]-2-fluoro-2-deoxy-ss-D-allose ([18F]2-FD ss A) for the detection of breast tumor. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2006
- Accelerated SPECT Monte Carlo Simulation using Multiple Projection Sampling and Convolution-based Forced Detection. IEEE Nuclear Science Symposium Conference Record. 3142-3147. 2006
- Convolution-Based Forced Detection Monte Carlo Simulation Incorporating Septal Penetration Modeling. IEEE Nuclear Science Symposium Conference Record. 2053-2057. 2006
- FLUORINE-18 LABELLED AROMATIC AMINO ACIDS FOR TUMOR IMAGING USING PET. Journal of Labelled Compounds and Radiopharmaceuticals. S216-S216. 2005
- An Investigation of Reconstruction Strategies for Mediastinal Lesion Detection Using Hybrid Ga-67 SPECT Images. IEEE Nuclear Science Symposium Conference Record. 1691-1694. 2005
- Investigating acquisition protocols for gated, dynamic myocardial imaging in PET and SPECT. IEEE Nuclear Science Symposium Conference Record. 3272-3275. 2004
- Assessment of scatter compensation strategies for Ga-67 tumor SPECT using numerical observers and human LROC studies. IEEE Nuclear Science Symposium Conference Record. 1035-1039. 2003
- Evaluation of the impact of 4D reconstruction algorithms in quantitative dynamic SPECT. IEEE Nuclear Science Symposium Conference Record. 1023-1026. 2003
- Ga-67 tumor detection using penalized-EM with nonanatomical regularizers. IEEE Nuclear Science Symposium Conference Record. 1397-1401. 2003
- Impact of respiratory motion on the detection of solitary pulmonary nodules with SPECT tumor imaging of NeoTect. IEEE Nuclear Science Symposium Conference Record. 838-841. 2003
- Reducing dynamic bladder artifact in pelvic bone SPECT: an assessment of lesion detectability using numerical and human observers. 2003 IEEE Nuclear Science Symposium. Conference Record (IEEE Cat. No.03CH37515). 2686-2689. 2003
- A comparison of triple energy window scatter compensation methods for Ga-67 tumour imaging.. Journal of Nuclear Medicine. 54P-54P. 2002
- Reducing bladder artifacts in clinical pelvic SPECT images.. Journal of Nuclear Medicine. 54P-54P. 2002
- An investigation into the impact of photon scatter in the detection of /sup 67/Ga tumours using Channelized Hotelling and human observers. IEEE Nuclear Science Symposium Conference Record. 2214-2218. 2002
- An investigation of projection sampling for Ga-67 tumor detection. IEEE Nuclear Science Symposium Conference Record. 2263-2267. 2002
- Modeling the respiratory motion of solitary pulmonary nodules for investigating SPECT tumor imaging. IEEE Nuclear Science Symposium Conference Record. 1371-1375. 2002
- Optimization of iterative reconstructions of /sup 99m/Tc cardiac SPECT studies using numerical observers. IEEE Nuclear Science Symposium Conference Record. 2156-2160. 2002
- Preliminary results of a clinical validation of the dSPECT method for determination of renal glomerular filtration rate (GFR). IEEE Nuclear Science Symposium Conference Record. 1079-1082. 2002
- Performance of the dSPECT method using radiopharmaceuticals with fast uptake and/or washout kinetics.. Journal of Nuclear Medicine. 46P-46P. 2001
- ROC optimization study of Tc-99m cardiac SPECT reconstructions with attenuation, scatter and resolution compensation using hybrid images.. Journal of Nuclear Medicine. 198P-198P. 2001
- Reduction of hot bladder artifact in pelvic imaging using single camera rotation dynamic SPECT (dSPECT).. Journal of Nuclear Medicine. 139P-140P. 2001
- Simultaneous emission-transmission imaging with Ga-67 and a Tc-99m scanning line source.. Journal of Nuclear Medicine. 196P-197P. 2001
- A dynamic expectation maximization algorithm for single camera rotation dynamic SPECT (dSPECT). IEEE Nuclear Science Symposium Conference Record. 15/31-15/35. 2000
- Assessment of performance for the dynamic SPECT (dSPECT) method. IEEE Nuclear Science Symposium Conference Record. 18/109-18/113. 2000
- Comparison of different figure of merit functions for dynamic single photon emission computed tomography (dSPECT). IEEE Nuclear Science Symposium Conference Record. 15/151-15/155. 2000
- The impact of noisy attenuation maps and patient motion on human-observer performance at Ga-67 lesion detection in SPECT. IEEE Nuclear Science Symposium Conference Record. 13/10-13/14. 2000
- The application of dynamic SPECT imaging (dSPECT) to renal imaging.. Journal of Nuclear Medicine. 198P-198P. 2000
- Dynamic SPECT imaging using a single camera rotation (dSPECT). IEEE Transactions on Nuclear Science. 1055-1061. 1999
- The incorporation of organ uptake into dynamic SPECT (dSPECT) image reconstruction. IEEE Nuclear Science Symposium Conference Record. 1132-1136. 1999
- Kinetic parameter estimation from dynamic SPECT studies.. Journal of Nuclear Medicine. 65P-65P. 1998
- Three approaches to dynamic SPECT imaging. IEEE Nuclear Science Symposium Conference Record. 1451-1455. 1998
- Dynamic heart-in-thorax phantom for functional SPECT. IEEE Transactions on Nuclear Science. 1600-1605. 1997
- Dynamic heart-in-thorax phantom for functional SPECT. IEEE Nuclear Science Symposium Conference Record. 1893-1897. 1997
- Thorax phantom for dynamic functional SPECT imaging. Journal of Nuclear Medicine. 991-991. 1996
- Quantification of I-131 uptake in metastases from thyroid carcinoma. IRPA9 - 1996 INTERNATIONAL CONGRESS ON RADIATION PROTECTION / NINTH INTERNATIONAL CONGRESS OF THE INTERNATIONAL RADIATION PROTECTION ASSOCIATION, PROCEEDINGS, VOL 3. C503-C503. 1996
- Comparison of ventilation defects quantified by Technegas V-SPECT and hyperpolarized 129Xe MRI. Proceedings of the International Society for Magnetic Resonance in Medicine ... Scientific Meeting and Exhibition..
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journal articles
- Sarcopenia in long‐term survivors of cancer in childhood and adolescence: A cross‐sectional study of calf muscle mass by peripheral quantitative computed tomography with an examination of the muscle–bone unit. Pediatric Blood and Cancer. 71:e30705. 2024
- The Nutritional Burden of Cancer: Nutritional Status and Body Composition Differences Between Children with Acute Lymphoblastic Leukemia and their Siblings in Guatemala. Nutrition and Cancer. 76:1-7. 2024
- Molecular brain differences and cannabis involvement: A systematic review of positron emission tomography studies. Journal of Psychiatric Research. 162:44-56. 2023
- Safety and Efficacy of Alendronate to Treat Osteopenia in Children During Therapy for Acute Lymphoblastic Leukemia: A Retrospective Cohort Study of Sequential Outcomes. Journal of Pediatric Hematology/Oncology. 45:200-206. 2023
- Comparison of ventilation defects quantified by Technegas SPECT and hyperpolarized 129Xe MRI. Frontiers in Physiology. 14:1133334. 2023
- The Influence of Body Composition on Bone Health in Long-term Survivors of Acute Lymphoblastic Leukemia in Childhood and Adolescence: Analyses by Dual-energy Radiograph Absorptiometry and Peripheral Quantitative Computed Tomography. Journal of Pediatric Hematology/Oncology. 44:423-431. 2022
- Ventilation and perfusion abnormalities following recovery from noncritical COVID-19. Canadian Journal of Respiratory, Critical Care, and Sleep Medicine. 6:304-313. 2022
- Use of pressure sensitive adhesives to create flexible ballistic composite laminates from UHMWPE fabric. Composite Structures. 287:115362-115362. 2022
- Use of patterned thermoplastic hot film to create flexible ballistic composite laminates from UHMWPE fabric. Materials and Design. 214:110403-110403. 2022
- Bone health in long‐term survivors of pediatric acute lymphoblastic leukemia. An assessment by peripheral quantitative computed tomography. Pediatric Blood and Cancer. 68:e29218. 2021
- Relationships of Bone Mineral Density to Whole Body Mass, Fat Mass and Fat-free Mass in Long-term Survivors of Acute Lymphoblastic Leukemia in Childhood. Journal of Pediatric Hematology/Oncology. 43:12-17. 2021
- Maternal and child factors associated with bone length traits in children at 3 years of age. Bone. 127:1-8. 2019
- Body composition in long‐term survivors of acute lymphoblastic leukemia diagnosed in childhood and adolescence: A focus on sarcopenic obesity. Cancer. 124:1225-1231. 2018
- The Dopamine Allosteric Agent, PAOPA, Demonstrates Therapeutic Potential in the Phencyclidine NMDA Pre-clinical Rat Model of Schizophrenia. Frontiers in Behavioral Neuroscience. 12:302. 2018
- A Comparison Between GATE and Accelerated Convolution-Based Forced Detection SIMIND for Low- and Medium-Energy Collimators: A Simulation Study. IEEE Transactions on Radiation and Plasma Medical Sciences. 1:36-45. 2017
- Characterization of 3-Dimensional PET Systems for Accurate Quantification of Myocardial Blood Flow. Journal of Nuclear Medicine. 58:103-109. 2017
- A Kernel Density Estimator-Based Maximum A Posteriori Image Reconstruction Method for Dynamic Emission Tomography Imaging. IEEE Transactions on Image Processing. 25:2233-2248. 2016
- An Adaptation of the Distance Driven Projection Method for Single Pinhole Collimators in SPECT Imaging. IEEE Transactions on Nuclear Science. 63:140-150. 2016
- Measuring the mutual effects between a CZT detector and MRI for the development of a simultaneous MBI/MRI insert. EJNMMI Physics. 2:A50. 2015
- Simultaneous <sup>99m</sup>tc/<sup>111</sup>in spect reconstruction using accelerated convolution-based forced detection monte carlo. IEEE Transactions on Nuclear Science. 62:2085-2095. 2015
- A standardized infrared imaging technique that specifically detects UCP1-mediated thermogenesis in vivo. Molecular Metabolism. 3:490-494. 2014
- Effects of MK-801 treatment across several pre-clinical analyses including a novel assessment of brain metabolic function utilizing PET and CT fused imaging in live rats. Neuropharmacology. 77:325-333. 2014
- Airway and pulmonary vascular measurements using contrast-enhanced micro-CT in rodents. American Journal of Physiology - Lung Cellular and Molecular Physiology. 304:L831-L843. 2013
- Correlative single photon emission computed tomography imaging of [123I]altropane binding in the rat model of Parkinson's. Nuclear Medicine and Biology. 38:741-749. 2011
- Evaluation of allergic lung inflammation by computed tomography in a rat model in vivo. European Respiratory Journal. 33:1437-1447. 2009
- Comparison between conventional and "clinical" assessment of experimental lung fibrosis. Journal of Translational Medicine. 6:16. 2008
- An evaluation of iterative reconstruction strategies based on mediastinal lesion detection using hybrid Ga‐67 SPECT images. Medical Physics. 35:4808-4815. 2008
- Convolution-Based Forced Detection Monte Carlo Simulation Incorporating Septal Penetration Modeling. IEEE Transactions on Nuclear Science. 55:967-974. 2008
- The use of small animal imaging in respiratory disease drug discovery. Drug Discovery Today: Therapeutic Strategies. 5:81-85. 2008
- Software‐based respiratory gating for small animal conebeam CT. Medical Physics. 35:1785-1792. 2008
- Isostructural fluorescent and radioactive probes for monitoring neural stem and progenitor cell transplants. Nuclear Medicine and Biology. 35:159-169. 2008
- Accelerated SPECT Monte Carlo Simulation Using Multiple Projection Sampling and Convolution-Based Forced Detection. IEEE Transactions on Nuclear Science. 55:560-567. 2008
- Three-dimensional computed tomography imaging in an animal model of emphysema. European Respiratory Journal. 30:1082-1089. 2007
- An evaluation of iterative reconstruction strategies on mediastinal lesion detection using hybrid Ga-67 SPECT images. IEEE Nuclear Science Symposium Conference Record. 5:3486-3490. 2007
- Reducing Artifacts in Pelvic Bone SPECT: An Assessment of Lesion Detectability Using Numerical and Human Observers. IEEE Transactions on Nuclear Science. 53:2808-2813. 2006
- Simultaneous assessment of cardiac perfusion and function using 5-dimensional imaging with Tc-99m teboroxime. Journal of Nuclear Cardiology. 13:354-361. 2006
- Reducing bladder artifacts in clinical pelvic SPECT images.. Journal of Nuclear Medicine. 45:1309-1314. 2004
- Assessment of scatter compensation strategies for (67)Ga SPECT using numerical observers and human LROC studies.. Journal of Nuclear Medicine. 45:802-812. 2004
- An Overview of Attenuation and Scatter Correction of Planar and SPECT Data for Dosimetry Studies. Cancer Biotherapy and Radiopharmaceuticals. 18:181-190. 2003
- An optimization of reconstruction parameters and investigation into the impact of photon scatter in /sup 67/Ga SPECT. IEEE Transactions on Nuclear Science. 49:2148-2154. 2002
- Comparison of scatter compensation strategies for myocardial perfusion imaging using Tc-99m labeled sestamibi. IEEE Transactions on Nuclear Science. 49:2309-2314. 2002
- Optimization of iterative reconstructions of /sup 99m/Tc cardiac SPECT studies using numerical observers. IEEE Transactions on Nuclear Science. 49:2355-2360. 2002
- Comparison of different figure of merit functions for dynamic single photon emission computed tomography (dSPECT). IEEE Transactions on Nuclear Science. 49:761-767. 2002
- The impact of noisy and misaligned attenuation maps on human-observer performance at lesion detection in SPECT. IEEE Transactions on Nuclear Science. 49:753-760. 2002
- Comparison of scatter compensation strategies for cardiac perfusion imaging using Tc-99m labeled sestamibi. IEEE Nuclear Science Symposium Conference Record. 4:2188-2192. 2002
- Introduction to the physics of molecular imaging with radioactive tracers in small animals. Journal of cellular biochemistry. Supplement. 87:221-230. 2002
- The incorporation of organ uptake into dynamic SPECT (dSPECT) image reconstruction. IEEE Transactions on Nuclear Science. 48:3-9. 2001
- Performance of the dynamic single photon emission computed tomography (dSPECT) method for decreasing or increasing activity changes. Physics in Medicine and Biology. 45:3525-3543. 2000
- An evaluation of dynamic SPECT imaging methods. IEEE Nuclear Science Symposium Conference Record. 3:1959-1963. 1999
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preprints
- Safety and efficacy of alendronate to treat osteopenia in children during therapy for acute lymphoblastic leukemia. A retrospective cohort study of sequential outcomes. 2022
- Bone health in long-term survivors of acute lymphoblastic leukemia in children and ado-lecents. An assessment by peripheral quantitative computed tomography 2021