Journal article
A standardized infrared imaging technique that specifically detects UCP1-mediated thermogenesis in vivo
Abstract
The activation and expansion of brown adipose tissue (BAT) has emerged as a promising strategy to counter obesity and the metabolic syndrome by increasing energy expenditure. The subsequent testing and validation of novel agents that augment BAT necessitates accurate pre-clinical measurements in rodents regarding the capacity for BAT-derived thermogenesis. We present a novel method to measure BAT thermogenesis using infrared imaging following …
Authors
Crane JD; Mottillo EP; Farncombe TH; Morrison KM; Steinberg GR
Journal
Molecular Metabolism, Vol. 3, No. 4, pp. 490–494
Publisher
Elsevier
Publication Date
7 2014
DOI
10.1016/j.molmet.2014.04.007
ISSN
2212-8778