Assessment of Scatter Compensation Strategies for 67Ga Tumor SPECT Using Numerical Observers and Human LROC Studies

Ga-67 citrate SPECT imaging is often used for oncological studies in order to diagnose or stage patient lymphomas. Because the decay of Ga-67 involves multiple emission energies, it is possible that many down-scattered photons will be present in photopeak acquisition data. We have previously shown through human observer LROC studies, that the inclusion of these scattered photons significantly degrades lesion detectability in simulations. We …