Collimator-Detector Response Compensation in Quantitative SPECT Reconstruction

The purpose of this study was to investigate the importance of collimator-detector response compensation in single photon emission computed tomography (SPECT). The compensation methods included in this study addressed three important degrading factors, which are attenuation, scatter and collimator-detector response (CDR). Geometric response (GR) and septal penetration (SP) are two most important components of collimator-detector response. The …