Simultaneous $^{99m}{\hbox {Tc}}/^{111}{\hbox {In}}$ SPECT Reconstruction Using Accelerated Convolution-Based Forced Detection Monte Carlo

Simultaneous multi-isotope Single Photon Emission Computed Tomography (SPECT) imaging has a number of applications in cardiac, brain, and cancer imaging. The major concern however, is the significant crosstalk contamination due to photon scatter between the different isotopes. The current study focuses on a method of crosstalk compensation between two isotopes in simultaneous dual isotope SPECT acquisition applied to cancer imaging using 99mTc …