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Evaluation of allergic lung inflammation by...
Journal article

Evaluation of allergic lung inflammation by computed tomography in a rat model in vivo

Abstract

The ability of micro-computed tomography (CT) to noninvasively evaluate allergic pulmonary inflammation in an experimental model was investigated. In addition, two image segmentation methods and the value of respiratory gating were investigated in the context of this model. Brown Norway rats were exposed to one of four doses of house dust mite (HDM) extract (0, 0.15, 15 or 150 microg) delivered intratracheally every 24 h for 10 days. CT …

Authors

Jobse BN; Johnson JR; Farncombe TH; Labiris R; Walker TD; Goncharova S; Jordana M

Journal

European Respiratory Journal, Vol. 33, No. 6, pp. 1437–1447

Publisher

European Respiratory Society (ERS)

Publication Date

6 2009

DOI

10.1183/09031936.00087508

ISSN

0903-1936