Thiazoles Concept

subject area of

• A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis  Journal Articles
• A PIK3CA-mutant breast cancer metastatic patient-derived organoid approach to evaluate alpelisib treatment for multiple secondary lesions  Journal Articles
• A Phase III Randomized Trial of the Timing of Meloxicam With Iodine-125 Prostate Brachytherapy  Journal Articles
• A phase 2 PK/PD study of andexanet alfa for reversal of rivaroxaban and edoxaban anticoagulation in healthy volunteers  Journal Articles
• A prospective evaluation of edoxaban compared to warfarin in subjects undergoing cardioversion of atrial fibrillation: The EdoxabaN vs. warfarin in subjectS UndeRgoing cardiovErsion of Atrial Fibrillation (ENSURE-AF) study  Journal Articles
• A randomized phase II study of cediranib alone versus cediranib in combination with dasatinib in docetaxel resistant, castration resistant prostate cancer patients  Journal Articles
• Accuracy of a Rapid Diagnostic Test for the Presence of Direct Oral Factor Xa or Thrombin Inhibitors in Urine—A Multicenter Trial  Journal Articles
• Actin Filaments Facilitate Insulin Activation of the Src and Collagen Homologous/Mitogen-activated Protein Kinase Pathway Leading to DNA Synthesis and c-fos Expression  Journal Articles
• Actin filaments participate in the relocalization of phosphatidylinositol3-kinase to glucose transporter-containing compartments and in the stimulation of glucose uptake in 3T3-L1 adipocytes  Journal Articles
• Advantages and limitations of the new anticoagulants  Journal Articles
• Altered dopamine D2-like receptor binding in rats with behavioral sensitization to quinpirole: effects of pre-treatment with Ro 41-1049  Journal Articles
• Analysis of the potency of various low molecular weight chemical chaperones to prevent protein aggregation  Journal Articles
• Andexanet Alfa for Specific Anticoagulation Reversal in Patients with Acute Bleeding during Treatment with Edoxaban  Journal Articles
• Benzodiazepine-induced inhibition of human malignant melanoma (M-6) cell growth.  Journal Articles
• Bicyclic thiazolidine lactam peptidomimetics of the dopamine receptor modulating peptide Pro-Leu-Gly-NH2  Journal Articles
• Bivariate evaluation of thromboembolism and bleeding in clinical trials of anticoagulants in patients with atrial fibrillation  Journal Articles
• Bleeding and antidotes in new oral anticoagulants  Journal Articles
• Bleeding with Direct Oral Anticoagulants vs Warfarin: Clinical Experience  Journal Articles
• Bleeding with direct oral anticoagulants vs warfarin: clinical experience  Journal Articles
• Cardioversion of Atrial Fibrillation in ENGAGE AF‐TIMI 48  Journal Articles
• Cerebrovascular Events in 21 105 Patients With Atrial Fibrillation Randomized to Edoxaban Versus Warfarin  Journal Articles
• Cholinergic Surveillance over Hippocampal RNA Metabolism and Alzheimer's-Like Pathology  Journal Articles
• Clinical Experience With the New Oral Anticoagulants for Treatment of Venous Thromboembolism  Journal Articles
• Clinical Impact of Bleeding in Cancer-Associated Venous Thromboembolism: Results from the Hokusai VTE Cancer Study  Journal Articles
• Clinical Implications of Reversal Agents for Direct Oral Anticoagulants  Journal Articles
• Clorgyline-induced switch from locomotion to mouthing in sensitization to the dopamine D2/D3 agonist quinpirole in rats: role of sigma and imidazoline I2 receptors  Journal Articles
• Clothianidin alters leukocyte profiles and elevates measures of oxidative stress in tadpoles of the amphibian, Rana pipiens  Journal Articles
• Comparative effectiveness and safety of the novel oral anticoagulants: do the pivotal clinical trials point to a new paradigm?  Journal Articles
• Comparison of the effects of gastric antisecretory agents in healthy volunteers and patients with duodenal ulcer.  Journal Articles
• Controlling the Morphology of Organic Crystals with Filamentous Bacteriophages  Journal Articles
• Crosstalk between Notch and Sonic hedgehog signaling in a mouse model of amyotrophic lateral sclerosis  Journal Articles
• Decreased epithelial barrier function evoked by exposure to metabolic stress and nonpathogenicE. coliis enhanced by TNF-α  Journal Articles
• Design, Synthesis, and Dopamine Receptor Modulating Activity of Spiro Bicyclic Peptidomimetics ofl-Prolyl-l-leucyl-glycinamide  Journal Articles
• Detection and quantification of endoplasmic reticulum stress in living cells using the fluorescent compound, Thioflavin T  Journal Articles
• Different binding sites for the neuropeptide Y Y1 antagonists 1229U91 and J-104870 on human Y1 receptors  Journal Articles
• Direct Oral Anticoagulants for Stroke Prevention in Patients With Device-Detected Atrial Fibrillation: A Study-Level Meta-Analysis of the NOAH-AFNET 6 and ARTESiA Trials  Journal Articles
• Direct oral anticoagulants compared with vitamin K antagonists for acute venous thromboembolism: evidence from phase 3 trials  Journal Articles
• Direct oral anticoagulants compared with vitamin K antagonists for acute venous thromboembolism: evidence from phase 3 trials.  Journal Articles
• Direct oral anticoagulants: evidence and unresolved issues  Journal Articles
• Dose reduction of edoxaban preserves efficacy and safety for the treatment of venous thromboembolism  Journal Articles
• Dynamic relationships between age, amyloid-β deposition, and glucose metabolism link to the regional vulnerability to Alzheimer’s disease  Journal Articles
• Dyspepsia  Journal Articles
• ENNOBLE-ATE trial: an open-label, randomised, multi-centre, observational study of edoxaban for children with cardiac diseases at risk of thromboembolism  Journal Articles
• Edoxaban and amiodarone: interactions on multiple levels  Journal Articles
• Edoxaban for the Prevention of Thromboembolism in Patients With Atrial Fibrillation and Bioprosthetic Valves  Journal Articles
• Edoxaban for the Treatment of Cancer-Associated Venous Thromboembolism  Journal Articles
• Edoxaban for the Treatment of Venous Thromboembolism in Patients with Cancer  Journal Articles
• Edoxaban for treatment of venous thromboembolism in patient groups with different types of cancer: Results from the Hokusai VTE Cancer study  Journal Articles
• Edoxaban for treatment of venous thromboembolism in patients with cancer  Journal Articles
• Edoxaban for venous thromboembolism in patients with cancer: results from a non-inferiority subgroup analysis of the Hokusai-VTE randomised, double-blind, double-dummy trial  Journal Articles
• Edoxaban is non-inferior to low-molecular-weight heparin for treating cancer-associated venous thromboembolism  Journal Articles
• Edoxaban versus Warfarin in Patients with Atrial Fibrillation  Journal Articles
• Edoxaban versus enoxaparin–warfarin in patients undergoing cardioversion of atrial fibrillation (ENSURE-AF): a randomised, open-label, phase 3b trial  Journal Articles
• Effect of hyperthermia on liver cell lines: important findings for thermal therapy in hepatocellular carcinoma.  Journal Articles
• Effects of the NSAIDs meloxicam and indomethacin on cartilage proteoglycan synthesis and joint responses to calcium pyrophosphate crystals in dogs.  Journal Articles
• Efficacy and safety of a two‐drug direct‐acting antiviral agent regimen ruzasvir 180 mg and uprifosbuvir 450 mg for 12 weeks in adults with chronic hepatitis C virus genotype 1, 2, 3, 4, 5 or 6  Journal Articles
• Evaluation of peroxisome proliferator‐activated receptor agonists on interleukin‐5‐induced eosinophil differentiation  Journal Articles
• Evaluation of the MRX PT DOAC assay for detection of clinically relevant factor Xa inhibitor drug levels.  Journal Articles
• Evolving use of new oral anticoagulants for treatment of venous thromboembolism  Journal Articles
• Extended duration of anticoagulation with edoxaban in patients with venous thromboembolism: a post-hoc analysis of the Hokusai-VTE study  Journal Articles
• Extended treatment with edoxaban in cancer patients with venous thromboembolism: A post‐hoc analysis of the Hokusai‐VTE Cancer study  Journal Articles
• Factor Xa and thrombin as targets for new oral anticoagulants  Journal Articles
• Gastrointestinal Bleeding With Edoxaban Versus Warfarin  Journal Articles
• Haloperidol (but not ziprasidone) withdrawal potentiates sensitization to the hyperlocomotor effect of cocaine in mice  Journal Articles
• Identification of Small Molecule Chemical Inhibitors of the Collagen-Specific Chaperone Hsp47  Journal Articles
• Impact of Spontaneous Extracranial Bleeding Events on Health State Utility in Patients with Atrial Fibrillation: Results from the ENGAGE AF‐TIMI 48 Trial  Journal Articles
• Impact of age, comorbidity, and polypharmacy on the efficacy and safety of edoxaban for the treatment of venous thromboembolism: An analysis of the randomized, double-blind Hokusai-VTE trial  Journal Articles
• Inappropriate prescription of allopurinol and febuxostat and risk of adverse events in the elderly: results from the REPOSI registry  Journal Articles
• Incorporating edoxaban into the choice of anticoagulants for atrial fibrillation  Journal Articles
• Inhibition of Metabotropic Glutamate Receptor Signaling by the Huntingtin-binding Protein Optineurin  Journal Articles
• Inhibition of Microsurgical Thrombosis by the Platelet Glycoprotein IIb/IIIa Antagonist SR121566A  Journal Articles
• Inhibition of SREBP With Fatostatin Does Not Attenuate Early Diabetic Nephropathy in Male Mice  Journal Articles
• International Council for Standardization in Haematology (ICSH) Recommendations for Laboratory Measurement of Direct Oral Anticoagulants  Journal Articles
• Ischaemic and bleeding risk in atrial fibrillation with and without peripheral artery disease and efficacy and safety of full- and half-dose edoxaban vs. warfarin: insights from ENGAGE AF-TIMI 48  Journal Articles
• Laboratory Monitoring of Non–Vitamin K Antagonist Oral Anticoagulant Use in Patients With Atrial Fibrillation  Journal Articles
• Laboratory measurement of the direct oral anticoagulants  Journal Articles
• Linking Endogenous Factor Xa Activity, a Biologically Relevant Pharmacodynamic Marker, to Edoxaban Plasma Concentrations and Clinical Outcomes in the ENGAGE AF-TIMI 48 Trial  Journal Articles
• Magnetic resonance venography to assess thrombus resolution with edoxaban monotherapy versus parenteral anticoagulation/warfarin for symptomatic deep vein thrombosis: A multicenter feasibility study  Journal Articles
• Meloxicam selectively depresses the afterdischarge of rat spinal dorsal horn neurones in response to noxious stimulation  Journal Articles
• Merging the potential of microbial genetics with biological and chemical diversity: an even brighter future for marine natural product drug discovery  Journal Articles
• MicroRNA-mediated PTEN downregulation as a novel non-genetic mechanism of acquired resistance to PI3Kα inhibitors of head & neck squamous cell carcinoma.  Journal Articles
• Molecular Coproscopy: Dung and Diet of the Extinct Ground Sloth Nothrotheriops shastensis  Journal Articles
• NOAC monitoring, reversal agents, and post-approval safety and effectiveness evaluation: A cardiac safety research consortium think tank  Journal Articles
• New Anticoagulants for Atrial Fibrillation  Journal Articles
• New oral anticoagulant agents – general features and outcomes in subsets of patients  Journal Articles
• New oral anticoagulants for stroke prevention in atrial fibrillation: impact of study design, double counting and unexpected findings on interpretation of study results and conclusions  Journal Articles
• Nitrogen mustard drug resistant B-cell chronic lymphocytic leukemia as an in vivo model for crosslinking agent resistance  Journal Articles
• Novel Oral Factor Xa and Thrombin Inhibitors in the Management of Thromboembolism  Journal Articles
• Optimizing the safety of treatment for venous thromboembolism in the era of the direct oral anticoagulants  Journal Articles
• Oral Direct Factor Xa Inhibitors  Journal Articles
• Oral anticoagulants in coronary heart disease (Section IV) Position paper of the ESC Working Group on Thrombosis – Task Force on Anticoagulants in Heart Disease  Journal Articles
• Oral direct factor Xa inhibition with edoxaban for thromboprophylaxis after elective total hip replacement  Journal Articles
• Outcomes With Edoxaban Versus Warfarin in Patients With Previous Cerebrovascular Events  Journal Articles
• Outpatient Management in Patients with Venous Thromboembolism with Edoxaban: A Post Hoc Analysis of the Hokusai-VTE Study  Journal Articles
• Overview of the New Oral Anticoagulants  Journal Articles
• Oxidative Stress and Bioindicators of Reproductive Function in Pulp and Paper Mill Effluent Exposed White Sucker  Journal Articles
• Peri-operative Adverse Outcomes in Patients with Atrial Fibrillation Taking Warfarin or Edoxaban: Analysis of the ENGAGE AF-TIMI 48 Trial  Journal Articles
• Perioperative Management of Patients Taking Direct Oral Anticoagulants  Journal Articles
• Periprocedural antithrombotic and bridging therapy: recommendations for standardized reporting in patients with arterial indications for chronic oral anticoagulant therapy  Journal Articles
• Possible Applications for Dopaminergic Agents Following Traumatic Brain Injury: Part 2  Journal Articles
• Profile of Patients Diagnosed With Acute Venous Thromboembolism in Routine Clinical Practice: The RE-COVERY DVT/PE™ Study  Journal Articles
• Prokinetics for functional dyspepsia  Journal Articles
• Prolonged protection against exercise-induced bronchoconstriction by the leukotriene D4–receptor antagonist cinalukast☆☆☆★  Journal Articles
• Pyonitrins A–D: Chimeric Natural Products Produced by Pseudomonas protegens  Journal Articles
• Quality of life in patients aged 65 years and older with overactive bladder treated with mirabegron across eight European countries: Secondary analysis of BELIEVE.  Journal Articles
• Randomised, parallel-group, multicentre, multinational phase 2 study comparing edoxaban, an oral factor Xa inhibitor, with warfarin for stroke prevention in patients with atrial fibrillation  Journal Articles
• Recurrent venous thromboembolism in patients with pulmonary embolism and right ventricular dysfunction: a post-hoc analysis of the Hokusai-VTE study  Journal Articles
• Regulation of kynurenine biosynthesis during influenza virus infection  Journal Articles
• Reversal of Direct Oral Anticoagulants: Current Status and Future Directions  Journal Articles
• Rheological blends for drug delivery. II. Prolongation of nerve blockade, biocompatibility, and in vitro–in vivo correlations  Journal Articles
• Risk factors for gastrointestinal bleeding in patients with gastrointestinal cancer using edoxaban  Journal Articles
• SREBP inhibition ameliorates renal injury after unilateral ureteral obstruction  Journal Articles
• SREBP-1 Mediates Angiotensin II-Induced TGF-β1 Upregulation and Glomerular Fibrosis  Journal Articles
• Selective cytotoxicity of gemcitabine in bladder cancer cell lines  Journal Articles
• Sensitivity of multiple life stages of 2 freshwater mussel species (Unionidae) to various pesticides detected in Ontario (Canada) surface waters  Journal Articles
• Sensitivity of the early-life stages of freshwater mollusks to neonicotinoid and butenolide insecticides  Journal Articles
• Sensory and vascular changes in a rat monoarthritis model: prophylactic and therapeutic effects of meloxicam  Journal Articles
• Severity of renal impairment in patients with heart failure and atrial fibrillation: implications for non‐vitamin K antagonist oral anticoagulant dose adjustment  Journal Articles
• Spanish toxic oil syndrome: An isothiocyanate-derived compound cannot be substantiated as a causative agent  Journal Articles
• Stroke and Mortality Risk in Patients With Various Patterns of Atrial Fibrillation  Journal Articles
• Stroke prevention in AF: Of Asians and non-Asians  Journal Articles
• Stroke prevention in atrial fibrillation: Closing the gap  Journal Articles
• Superoxides from mitochondrial complex III: the role of manganese superoxide dismutase  Journal Articles
• Synthesis and Dopamine Receptor Modulating Activity of Substituted Bicyclic Thiazolidine Lactam Peptidomimetics of l-Prolyl-l-leucyl-glycinamide  Journal Articles
• The Non-Vitamin K Antagonist Oral Anticoagulants in Heart Disease: Section V—Special Situations  Journal Articles
• The Thiazole-5-Carboxamide GPS491 Inhibits HIV-1, Adenovirus, and Coronavirus Replication by Altering RNA Processing/Accumulation  Journal Articles
• The treatment effects of acotiamide in esophagogastric outflow obstruction: a prospective longitudinal observational study.  Journal Articles
• Troglitazone monotherapy improves glycemic control in patients with type 2 diabetes mellitus: a randomized, controlled study. The Troglitazone Study Group.  Journal Articles
• Usual On-therapy Ranges of Drug Concentrations in Patients with Atrial Fibrillation Treated with Direct Oral Anticoagulants: A Systematic Review and Meta-analysis.  Journal Articles
• Validation of pH Dataloggers for Pharmacologic Studies  Journal Articles
• Venous thromboembolism management: where do novel anticoagulants fit?  Journal Articles