Platelet Factor 4
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Overview
subject area of
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A Spontaneous Prothrombotic Disorder Resembling Heparin-induced Thrombocytopenia Academic Article
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A comparative study of platelet factor 4‐enhanced platelet activation assays for the diagnosis of heparin‐induced thrombocytopenia Academic Article
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A prospective study measuring the development of antibodies against platelet factor 4-heparin in healthy males after exposure to heparins Academic Article
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Abnormal megakaryocyte development and platelet function in Nbeal2−/− mice Academic Article
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Activation of platelets by sera containing igg1 heparin-dependent antibodies: an explanation for the predominance of the Fcγrlla “low responder” (his131) gene in patients with heparin-induced thrombocytopenia Academic Article
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Adjunct Immune Globulin for Vaccine-Induced Immune Thrombotic Thrombocytopenia Academic Article
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An Overview of the Heparin-Induced Thrombocytopenia Syndrome Academic Article
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An international external quality assessment for laboratory diagnosis of heparin-induced thrombocytopenia Academic Article
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Anti-PF4/heparin antibodies and venous graft occlusion in postcoronary artery bypass surgery patients randomized to postoperative unfractionated heparin or fondaparinux thromboprophylaxis Academic Article
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Anti-PF4/heparin antibody formation postorthopedic surgery thromboprophylaxis: the role of non-drug risk factors and evidence for a stoichiometry-based model of immunization Academic Article
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Antibody epitopes in vaccine-induced immune thrombotic thrombocytopaenia Academic Article
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Antiphospholipid and anti-PF4 antibodies: an association affecting anti-PF4/heparin assay analysis Academic Article
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Anti–platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein Academic Article
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Anti–platelet factor 4/heparin antibodies in orthopedic surgery patients receiving antithrombotic prophylaxis with fondaparinux or enoxaparin Academic Article
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Anti–protamine-heparin antibodies: incidence, clinical relevance, and pathogenesis Academic Article
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Autoimmune heparin-induced thrombocytopenia Academic Article
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B cells, PF4/heparin complexes, and complement Academic Article
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Benefit and risk of heparin for maintaining peripheral venous catheters in neonates: a placebo-controlled trial Academic Article
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Cellular immune responses to platelet factor 4 and heparin complexes in patients with heparin-induced thrombocytopenia Academic Article
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Characterization of platelet factor 4 amino acids that bind pathogenic antibodies in heparin‐induced thrombocytopenia Academic Article
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Chemistry, Measurement, and Clinical Significance of Platelet Specific Proteins Academic Article
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Clinical effectiveness of a Bayesian algorithm for the diagnosis and management of heparin-induced thrombocytopenia Academic Article
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Clinical picture of heparin-induced thrombocytopenia (HIT) and its differentiation from non-HIT thrombocytopenia Academic Article
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Clinical sample investigation (CSI) hematology: pinpointing the precise onset of heparin-induced thrombocytopenia (HIT) Academic Article
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Close Approximation of Two Platelet Factor 4 Tetramers by Charge Neutralization Forms the Antigens Recognized by HIT Antibodies Academic Article
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Combination of 4Ts score and PF4/H-PaGIA for diagnosis and management of heparin-induced thrombocytopenia: prospective cohort study Academic Article
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Combination of two complementary automated rapid assays for diagnosis of heparin‐induced thrombocytopenia (HIT) Academic Article
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Combined use of the high heparin step and optical density to optimize diagnostic sensitivity and specificity of an anti-PF4/heparin enzyme-immunoassay Academic Article
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Confirmatory procedure and other maneuvers to assess pathogenicity of platelet factor 4 (PF4)-dependent antibodies – distinguishing "signal" from "noise" Academic Article
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Delayed-Onset Heparin-Induced Thrombocytopenia and Cerebral Thrombosis after a Single Administration of Unfractionated Heparin Academic Article
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Delayed-Onset Heparin-Induced Thrombocytopenia and Thrombosis Academic Article
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Delayed-onset HIT caused by low-molecular-weight heparin manifesting during fondaparinux prophylaxis Academic Article
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Development of a high-yield expression and purification system for platelet factor 4 Academic Article
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Diagnostic accuracy of IgG-specific versus polyspecific enzyme-linked immunoassays in heparin-induced thrombocytopenia: a systematic review and meta-analysis Academic Article
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Distinguishing between anti-platelet factor 4/heparin antibodies that can and cannot cause heparin-induced thrombocytopenia Academic Article
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Early-onset and persisting thrombocytopenia in post-cardiac surgery patients is rarely due to heparin-induced thrombocytopenia, even when antibody tests are positive Academic Article
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Effect of anti-platelet factor-4/heparin antibody induction on early saphenous vein graft occlusion after coronary artery bypass surgery Academic Article
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Evidence for thrombin binding to dermatan sulphate sites in the rabbit aorta subendothelium in vitro Academic Article
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FcγRIIa proteolysis as a diagnostic biomarker for heparin-induced thrombocytopenia Academic Article
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Fibrinogen proteolysis and platelet alpha-granule release in preeclampsia/eclampsia Academic Article
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Fibronectin modulates formation of PF4/heparin complexes and is a potential factor for reducing risk of developing HIT Academic Article
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Fondaparinux thromboprophylaxis-associated heparin-induced thrombocytopenia syndrome complicated by arterial thrombotic stroke Academic Article
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Fondaparinux: does it cause HIT? can it treat HIT? Academic Article
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Formation of anti–platelet factor 4/heparin antibodies after cardiac surgery: Influence of perioperative platelet activation, the inflammatory response, and histocompatibility leukocyte antigen status Academic Article
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Frequency of positive anti-PF4/polyanion antibody tests after COVID-19 vaccination with ChAdOx1 nCoV-19 and BNT162b2 Academic Article
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HITlights: A career perspective on heparin-induced thrombocytopenia Academic Article
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Hemodialysis-Associated Acute Systemic Reactions and Heparin-Induced Thrombocytopenia Academic Article
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Heparin-Induced Thrombocytopenia Academic Article
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Heparin-Induced Thrombocytopenia Academic Article
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Heparin-Induced Thrombocytopenia Academic Article
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Heparin-Induced Thrombocytopenia in Patients with Ventricular Assist Devices: Are New Prevention Strategies Required? Academic Article
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Heparin-Induced Thrombocytopenia: A Ten-Year Retrospective Academic Article
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Heparin-induced thrombocytopenia Academic Article
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Heparin-induced thrombocytopenia - therapeutic concentrations of danaparoid, unlike fondaparinux and direct thrombin inhibitors, inhibit formation of platelet factor 4-heparin complexes Academic Article
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Heparin-induced thrombocytopenia: A stoichiometry-based model to explain the differing immunogenicities of unfractionated heparin, low-molecular-weight heparin, and fondaparinux in different clinical settings Academic Article
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Heparin-induced thrombocytopenia: a prospective study on the incidence, platelet-activating capacity and clinical significance of antiplatelet factor 4/heparin antibodies of the IgG, IgM, and IgA classes Academic Article
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Heparin-induced thrombocytopenia: towards standardization of platelet factor 4/heparin antigen tests Academic Article
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Heterogeneity of Vaccine-Induced Immune Thrombotic Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination and Safety of Second Vaccination with BNT162b2 Academic Article
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High sensitivity and specificity of an automated IgG-specific chemiluminescence immunoassay for diagnosis of HIT Academic Article
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Human megakaryocytes. II. Expression of platelet proteins in early marrow megakaryocytes. Academic Article
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IV Immunoglobulin for Autoimmune Heparin-Induced Thrombocytopenia Academic Article
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Immune heparin-induced thrombocytopenia can occur in patients receiving clopidogrel and aspirin Academic Article
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Immunoglobulin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4 Academic Article
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Impact of the patient population on the risk for heparin-induced thrombocytopenia Academic Article
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Improving Clinical Interpretation of the Anti-Platelet Factor 4/Heparin Enzyme-Linked Immunosorbent Assay for the Diagnosis of Heparin-Induced Thrombocytopenia Through the Use of Receiver Operating Characteristic Analysis, Stratum-Specific Likelihood Ratios, and Bayes Theorem Academic Article
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In vivo platelet activation with in vitro hyperaggregability to arachidonic acid in renal allograft recipients. Academic Article
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Incidence and clinical relevance of anti–platelet factor 4/heparin antibodies before cardiac surgery Academic Article
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Increased Platelet Destruction Academic Article
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Increased heparin clearance in experimental pulmonary embolism. Academic Article
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Increased mortality in hemodialysis patients having specific antibodies to the platelet factor 4-heparin complex Academic Article
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Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia Academic Article
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Intraglomerular localization of platelet related antigens, platelet factor 4 and beta-thromboglobulin in glomerulonephritis. Academic Article
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Investigation of a platelet factor 4 polymorphism on the immune response in patients with heparin-induced thrombocytopenia Academic Article
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Laboratory diagnosis of heparin‐induced thrombocytopenia Academic Article
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Laboratory testing for VITT antibodies Academic Article
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Laboratory testing for heparin-induced thrombocytopenia. Academic Article
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Laboratory testing for heparin-induced thrombocytopenia: a conceptual framework and implications for diagnosis Academic Article
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Lessons from vaccine-induced immune thrombotic thrombocytopenia Academic Article
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Limitations of the particle immunofiltration assay test for diagnosis of heparin‐induced thrombocytopenia Academic Article
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Management of heparin-induced thrombocytopenia Academic Article
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Measurement of platelet release substances in glomerulonephritis: A comparison of beta-thromboglobulin (β-TG), platelet factor 4 (PF4) and serotonin assays Academic Article
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Neutralization of Heparin Activity Academic Article
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New Approaches to the Diagnosis of Heparin-Induced Thrombocytopenia Academic Article
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No significant improvement in diagnostic specificity of an anti-PF4/polyanion immunoassay with use of high heparin confirmatory procedure Academic Article
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Nonheparin Anticoagulants for Heparin-Induced Thrombocytopenia Academic Article
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Optical Densities Reduce Odds of Heparin-induced Thrombocytopenia Over-diagnosis Academic Article
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PF4-dependent immunoassays and inferential detection of HIT antibodies Academic Article
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Performance characteristics of a rapid assay for anti-PF4/heparin antibodies: the particle immunofiltration assay Academic Article
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Performance characteristics of an automated latex immunoturbidimetric assay [HemosIL ® HIT-Ab (PF4-H) ] for the diagnosis of immune heparin-induced thrombocytopenia Academic Article
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Plasma exchange to remove HIT antibodies: dissociation between enzyme-immunoassay and platelet activation test reactivities Academic Article
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Platelet Activation Testing for Heparin-Induced Thrombocytopenia Antibodies Academic Article
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Platelet count recovery and seroreversion in immune HIT despite continuation of heparin: further observations and literature review Academic Article
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Platelet factor 4 inhibits ADAMTS13 activity and regulates the multimeric distribution of von Willebrand factor Academic Article
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Platelet-Activating Antibodies Are Detectable at the Earliest Onset of Heparin-Induced Thrombocytopenia, With Implications for the Operating Characteristics of the Serotonin-Release Assay Academic Article
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Platelet-activating anti-PF4 antibodies mimicking VITT antibodies in an unvaccinated patient with monoclonal gammopathy Academic Article
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Platelet-activating anti-PF4 disorders: An overview Academic Article
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Platelet‐activating immune complexes identified in critically ill COVID‐19 patients suspected of heparin‐induced thrombocytopenia Academic Article
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Predictive value of the 4Ts scoring system for heparin-induced thrombocytopenia: a systematic review and meta-analysis Academic Article
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Prevalence and Risk of Preexisting Heparin-Induced Thrombocytopenia Antibodies in Patients With Acute VTE Academic Article
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Prevalence and clinical implications of anti-PF4/heparin antibodies in intensive care patients: a prospective observational study Academic Article
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Prognostic importance of preoperative anti-PF4/heparin antibodies in patients undergoing cardiac surgery Academic Article
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Prospective multicentre cohort study of heparin-induced thrombocytopenia in acute ischaemic stroke patients Academic Article
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Protamine (heparin)-induced thrombocytopenia: a review of the serological and clinical features associated with anti-protamine/heparin antibodies Academic Article
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Quantitative interpretation of optical density measurements using PF4-dependent enzyme-immunoassays Academic Article
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Recognition, treatment, and prevention of heparin-induced thrombocytopenia: Review and update Academic Article
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Released adenosine diphosphate stabilizes thrombin-induced human platelet aggregates Academic Article
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Risk of heparin-induced thrombocytopenia in patients receiving thromboprophylaxis Academic Article
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Serotonin‐release assay‐negative heparin‐induced thrombocytopenia Academic Article
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Serotonin‐release assay‐positive but platelet factor 4‐dependent enzyme‐immunoassay negative:
HIT
or not
HIT
? Academic Article
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Spontaneous HIT syndrome: Knee replacement, infection, and parallels with vaccine-induced immune thrombotic thrombocytopenia Academic Article
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Studies of the antiâplatelet factor 4/heparin immune response: adapting the enzyme-linked immunosorbent spot assay for detection of memory B cells against complex antigens Academic Article
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Studies of the immune response in heparin-induced thrombocytopenia Academic Article
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Studies of α-granule proteins in cultured human megakaryocytes Academic Article
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Testing for Heparin-Induced Thrombocytopenia Antibodies Academic Article
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Testing for heparin-induced thrombocytopenia: are we there yet? Academic Article
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The Pathophysiology of Heparin-Induced Thrombocytopenia Academic Article
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The effects of high-dose heparin on inflammatory and coagulation parameters following cardiopulmonary bypass Academic Article
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The epitope specificity of heparin‐induced thrombocytopenia Academic Article
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The mechanism of action of thrombin inhibitors. Academic Article
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The prevalence of antibodies to the platelet factor 4 -heparin complex and association with access thrombosis in patients on chronic hemodialysis Academic Article
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The role of fluid-phase immune complexes in the pathogenesis of heparin-induced thrombocytopenia Academic Article
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The serological profile of early-onset and persisting post-cardiac surgery thrombocytopenia complicated by “true” heparin-induced thrombocytopenia Academic Article
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The serological profile of fondaparinux-associated heparin-induced thrombocytopenia syndrome Academic Article
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The temporal profile of the anti-PF4/heparin immune response Academic Article
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The use of well-characterized sera for the assessment of new diagnostic enzyme-immunoassays for the diagnosis of heparin-induced thrombocytopenia Academic Article
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Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination Academic Article
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Transient pseudothrombocytopenia associated with immune heparin-induced thrombocytopenia complicated by pulmonary embolism Academic Article
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Treatment of vaccine-induced immune thrombotic thrombocytopenia (VITT) Academic Article
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When is HIT Really HIT? Academic Article