International Normalized Ratio Concept

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• A Comparison of Three Months of Anticoagulation with Extended Anticoagulation for a First Episode of Idiopathic Venous Thromboembolism  Journal Articles
• A Comparison of Two Intensities of Warfarin for the Prevention of Recurrent Thrombosis in Patients with the Antiphospholipid Antibody Syndrome  Journal Articles
• A Computer Generated Induction System for Hospitalized Patients Starting on Oral Anticoagulant Therapy  Journal Articles
• A New, Simplified Measure of Anticoagulation Control With Warfarin: Potential Role in the Direct Oral Anticoagulant Era  Journal Articles
• A Randomized Trial Comparing 5-mg and 10-mg Warfarin Loading Doses  Journal Articles
• A cohort study of coagulation parameters and the use of blood products in surgery of the thoracic and thoracoabdominal aorta  Journal Articles
• A comparison of dabigatran etexilate with warfarin in patients with mechanical heart valves: The Randomized, phase II study to Evaluate the sAfety and pharmacokinetics of oraL dabIGatran etexilate in patients after heart valve replacemeNt (RE-ALIGN)  Journal Articles
• A multicentre randomised assessment of the DAWN AC computer-assisted oral anticoagulant dosage program  Journal Articles
• A multicentre randomised clinical endpoint study of parma 5 computer‐assisted oral anticoagulant dosage  Journal Articles
• A prospective study of an aggressive warfarin dosing algorithm to reach and maintain INR 2 to 3 after heart valve surgery  Journal Articles
• A team-based approach to warfarin management in long term care: A feasibility study of the MEDeINR electronic decision support system  Journal Articles
• American Society of Hematology 2018 guidelines for management of venous thromboembolism: optimal management of anticoagulation therapy  Journal Articles
• An international multicenter randomized study of computer-assisted oral anticoagulant dosage vs. medical staff dosage  Journal Articles
• Analysis of Warfarin Therapy in Pediatric Patients: A Prospective Cohort Study of 319 Patients  Journal Articles
• Anticoagulant failure in coagulopathic patients: PTT confounding and other pitfalls  Journal Articles
• Anticoagulant-Related Nephropathy  Journal Articles
• Anticoagulation Control with Daily Low‐Dose Vitamin K to Reduce Clinically Adverse Outcomes and International Normalized Ratio Variability: A Systematic Review and Meta‐Analysis  Journal Articles
• Antithrombotic Therapy for Atrial Fibrillation  Journal Articles
• Antithrombotic Therapy in Children*  Journal Articles
• Antithrombotic therapy for VTE disease: CHEST guideline and expert panel report  Journal Articles
• Antithrombotic therapy for VTE disease: antithrombotic therapy and prevention of thrombosis: American College of Chest Physicians evidence-based clinical practice guidelines  Journal Articles
• Approaches to investigating common bleeding disorders: An evaluation of North American coagulation laboratory practices  Journal Articles
• Are Brand-Name and Generic Warfarin Interchangeable? Multiple N-of-1 Randomized, Crossover Trials  Journal Articles
• Argatroban as a Heparin Substitute in Cases of Heparin-Induced Thrombocytopenia  Journal Articles
• Assessment of Anticoagulation Intensity and Management of Bleeding With Old and New Oral Anticoagulants  Journal Articles
• Azathioprine and inhibition of the anticoagulant effect of warfarin: Evidence from a case report and a literature review  Journal Articles
• Benefit of Oral Anticoagulant Over Antiplatelet Therapy in Atrial Fibrillation Depends on the Quality of International Normalized Ratio Control Achieved by Centers and Countries as Measured by Time in Therapeutic Range  Journal Articles
• Bile acids and coagulation factors  Journal Articles
• Brand Name versus Generic Warfarin: A Systematic Review of the Literature  Journal Articles
• Capillary Whole Blood Monitoring of Oral Anticoagulants in Children in Outpatient Clinics and the Home Setting  Journal Articles
• Cardioversion of Atrial Fibrillation in ENGAGE AF‐TIMI 48  Journal Articles
• Care of Patients Receiving Long-Term Anticoagulant Therapy  Journal Articles
• Clinical factors influencing the sensitivity to warfarin when restarted after surgery  Journal Articles
• Clopidogrel plus aspirin versus oral anticoagulation for atrial fibrillation in the Atrial fibrillation Clopidogrel Trial with Irbesartan for prevention of Vascular Events (ACTIVE W): a randomised controlled trial  Journal Articles
• Cluster randomized controlled trial of a simple warfarin maintenance dosing algorithm versus usual care among primary care practices  Journal Articles
• Coagulation Assays  Journal Articles
• Coagulopathy in a patient with nephrotic syndrome  Journal Articles
• Comment: Treatment of Heparin-Induced Thrombocytopenia  Journal Articles
• Comparison of Low-Intensity Warfarin Therapy with Conventional-Intensity Warfarin Therapy for Long-Term Prevention of Recurrent Venous Thromboembolism  Journal Articles
• Comparison of a daily fixed 2.5-mg warfarin dose with a 5-mg, international normalized ratio adjusted, warfarin dose initially following heart valve replacement  Journal Articles
• Comparison of international normalized ratio audit parameters in patients enrolled in GARFIELD‐AF and treated with vitamin K antagonists  Journal Articles
• Critical Values in the Coagulation Laboratory Results of a Survey of the North American Specialized Coagulation Laboratory Association  Journal Articles
• Dabigatran etexilate and reduction in serum apolipoprotein B  Journal Articles
• Dabigatran is Less Effective Than Warfarin at Attenuating Mechanical Heart Valve‐Induced Thrombin Generation  Journal Articles
• Dabigatran versus Warfarin in the Treatment of Acute Venous Thromboembolism  Journal Articles
• Dalteparin Compared with an Oral Anticoagulant for Thromboprophylaxis in Patients with Cancer  Journal Articles
• Decreased Concentrations of Heparinoids Are Required to Inhibit Thrombin Generation in Plasma from Newborns and Children Compared to Plasma from Adults due to Reduced Thrombin Potential  Journal Articles
• Decreasing warfarin sensitivity during the first three months after heart valve surgery: Implications for dosing  Journal Articles
• Does Celecoxib Potentiate the Anticoagulant Effect of Warfarin? A Randomized, Double-Blind, Controlled Trial  Journal Articles
• Effect of Vitamin K Intake on the Stability of Treatment with Vitamin K Antagonists: A Systematic Review of the Literature  Journal Articles
• Effect of Warfarin on Activated Partial Thromboplastin Time in Patients Receiving Heparin  Journal Articles
• Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy  Journal Articles
• Effect of a simple two‐step warfarin dosing algorithm on anticoagulant control as measured by time in therapeutic range: a pilot study  Journal Articles
• Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: an analysis of the RE-LY trial  Journal Articles
• Elevated international normalized ratio is correlated with large volume transfusion in pediatric trauma patients  Journal Articles
• Establishing an Optimal Therapeutic Range for Coumarins  Journal Articles
• Evaluation of an initiation protocol of 4 mg of warfarin for atrial fibrillation in the outpatient setting.  Journal Articles
• Evidence-Based Management of Anticoagulant Therapy  Journal Articles
• Exaggerated initial response to warfarin following heart valve replacement  Journal Articles
• Examining therapeutic equivalence between branded and generic warfarin in Brazil: The WARFA crossover randomized controlled trial  Journal Articles
• Experiences of a low-intensity anticoagulation regimen for extended secondary prevention of venous thromboembolism  Journal Articles
• Extended Use of Dabigatran, Warfarin, or Placebo in Venous Thromboembolism  Journal Articles
• Failure to correct International Normalized Ratio and mortality among patients with warfarin‐related major bleeding: an analysis of electronic health records  Journal Articles
• Fondaparinux versus direct thrombin inhibitor therapy for the management of heparin-induced thrombocytopenia (HIT) – Bridging the River Coumarin  Journal Articles
• Frequency of venous thromboembolism in 6513 patients with COVID-19: a retrospective study  Journal Articles
• Gastrointestinal Bleeding With Edoxaban Versus Warfarin  Journal Articles
• Genetic Determinants of Warfarin Maintenance Dose and Time in Therapeutic Treatment Range: A RE-LY Genomics Substudy  Journal Articles
• Haemostatic genetic variants, ABO blood group and bleeding risk during oral anticoagulant treatment after cerebral ischaemia of arterial origin  Journal Articles
• Hemorrhagic Complications of Anticoagulant Treatment  Journal Articles
• Hemorrhagic Complications of Anticoagulant and Thrombolytic Treatment  Journal Articles
• High prevalence of abnormal preoperative coagulation tests in patients with adolescent idiopathic scoliosis  Journal Articles
• Home prophylactic warfarin anticoagulation program after hip and knee arthroplasty.  Journal Articles
• Incidence and risk factors for acute kidney injury in patients with excessive anticoagulation on warfarin: a retrospective study  Journal Articles
• Influenza Vaccination and Vitamin K Antagonist Treatment  Journal Articles
• Intensity of Warfarin Coagulation in the Antiphospholipid Syndrome  Journal Articles
• Interlaboratory variation in heparin monitoring: Lessons from the Quality Management Program of Ontario coagulation surveys  Journal Articles
• International Normalized Ratio Targets for Left-Sided Mechanical Valve Replacement  Journal Articles
• Intracranial Hemorrhage in Atrial Fibrillation Patients During Anticoagulation With Warfarin or Dabigatran  Journal Articles
• Intracranial and fatal bleeding according to indication for long‐term oral anticoagulant therapy  Journal Articles
• Laboratory Monitoring of Oral Vitamin K Anticoagulation  Journal Articles
• Loading dose vs. maintenance dose of warfarin for reinitiation after invasive procedures: a randomized trial  Journal Articles
• Low Dose Oral Vitamin K to Reverse Acenocoumarol-induced Coagulopathy: A Randomized Controlled Trial  Journal Articles
• Low dose oral vitamin K to reverse acenocoumarol-induced coagulopathy: a randomized controlled trial.  Journal Articles
• Low-Intensity Adjusted-Dose Warfarin for the Prevention of Hemodialysis Catheter Failure  Journal Articles
• Low-Intensity versus Conventional-Intensity Warfarin for Prevention of Recurrent Venous Thromboembolism  Journal Articles
• Low-Molecular-Weight Heparin as Bridging Anticoagulation During Interruption of Warfarin  Journal Articles
• Low-dose oral vitamin K is safe and effective for outpatient management of patients with an INR>10  Journal Articles
• Low-dose oral vitamin K therapy for the management of asymptomatic patients with elevated international normalized ratios: a brief review  Journal Articles
• Low-dose oral vitamin K to normalize the international normalized ratio prior to surgery in patients who require temporary interruption of warfarin  Journal Articles
• Low-dose warfarin in rehabilitating stroke survivors  Journal Articles
• Lower versus Standard INR Targets in Atrial Fibrillation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials  Journal Articles
• MELD Score as a Predictor of Early Death in Patients Undergoing Elective Transjugular Intrahepatic Portosystemic Shunt (TIPS) Procedures  Journal Articles
• Magnetic resonance venography to assess thrombus resolution with edoxaban monotherapy versus parenteral anticoagulation/warfarin for symptomatic deep vein thrombosis: A multicenter feasibility study  Journal Articles
• Management of Excessive Anticoagulant Effect Due to Vitamin K Antagonists  Journal Articles
• Managing Oral Anticoagulant Therapy  Journal Articles
• Managing oral anticoagulant therapy.  Journal Articles
• Meeting the Unmet Needs in Anticoagulant Therapy  Journal Articles
• Monitoring patients with the lupus anticoagulant while treated with vitamin K antagonists: communication from the SSC of the ISTH  Journal Articles
• Monitoring the anticoagulant effect after a massive rivaroxaban overdose  Journal Articles
• Mortality in vitamin K antagonist-related intracerebral bleeding treated with plasma or 4-factor prothrombin complex concentrate  Journal Articles
• New artificial intelligence prediction model using serial prothrombin time international normalized ratio measurements in atrial fibrillation patients on vitamin K antagonists: GARFIELD-AF  Journal Articles
• New oral anticoagulants in atrial fibrillation  Journal Articles
• Nonadherence with INR Monitoring and Anticoagulant Complications  Journal Articles
• Optimal Dosing of Subcutaneous Unfractionated Heparin for the Treatment of Deep Vein Thrombosis  Journal Articles
• Optimal Timing of Resumption of Warfarin After Intracranial Hemorrhage  Journal Articles
• Optimal reversal of vitamin K antagonists  Journal Articles
• Oral Anticoagulant Initiation: Rationale for the Use of Warfarin Dosing Nomograms  Journal Articles
• Oral Anticoagulant Therapy in Patients with Coronary Artery Disease  Journal Articles
• Oral Anticoagulation Treatment in the Elderly  Journal Articles
• Oral Rivaroxaban for the Treatment of Symptomatic Pulmonary Embolism  Journal Articles
• Oral Vitamin K Lowers the International Normalized Ratio More Rapidly Than Subcutaneous Vitamin K in the Treatment of Warfarin-Associated Coagulopathy  Journal Articles
• Oral Vitamin K Versus Placebo to Correct Excessive Anticoagulation in Patients Receiving Warfarin  Journal Articles
• Oral anticoagulants in patients with coronary artery disease  Journal Articles
• Oral vitamin K effectively treats international normalised ratio (INR) values in excess of 10  Journal Articles
• Oral vitamin K produces a normal INR within 24 hours of its administration in most patients discontinuing warfarin.  Journal Articles
• Oral-anticoagulant-related intracerebral hemorrhage  Journal Articles
• Orally Active Direct Thrombin Inhibitors  Journal Articles
• Organ-specific bleeding patterns of anticoagulant therapy: lessons from clinical trials  Journal Articles
• Outcomes and predictors of very stable INR control during chronic anticoagulation therapy  Journal Articles
• Paper-based dosing algorithms for maintenance of warfarin anticoagulation  Journal Articles
• Patient Self-Monitoring of Oral Anticoagulant Therapy  Journal Articles
• Patient preferences for capillary vs. venous INR determination in an anticoagulation clinic: a randomized controlled trial  Journal Articles
• Perioperative Management of Oral Anticoagulation  Journal Articles
• Perioperative Management of Patients Receiving Oral Anticoagulants  Journal Articles
• Perioperative Management of Patients Receiving Oral Anticoagulants  Journal Articles
• Perioperative anticoagulation management in patients who are receiving oral anticoagulant therapy: a practical guide for clinicians  Journal Articles
• Pharmacology and Management of the Vitamin K Antagonists  Journal Articles
• Plasma transfusion practices: A multicentre electronic audit  Journal Articles
• Practical issues with vitamin K antagonists: elevated INRs, low time-in-therapeutic range, and warfarin failure  Conferences
• Practical management of coagulopathy associated with warfarin  Journal Articles
• Practical management of coagulopathy associated with warfarin.  Journal Articles
• Praktische Behandlung der Warfarin-assoziierten Gerinnungsstörung  Journal Articles
• Predictors of post-thrombotic syndrome in a population with a first deep vein thrombosis and no primary venous insufficiency  Journal Articles
• Predictors of the post‐thrombotic syndrome during long‐term treatment of proximal deep vein thrombosis  Journal Articles
• Prevention and treatment of bleeding complications in patients receiving vitamin K antagonists, Part 1: Prevention  Journal Articles
• Pro: “Anti-platelet therapy is an alternative to oral anticoagulation for atrial fibrillation”  Journal Articles
• Proposal of a two‐step process for the diagnosis of sepsis‐induced disseminated intravascular coagulation  Journal Articles
• Prothrombin Complex Concentrates for Perioperative Vitamin K Antagonist and Non–vitamin K Anticoagulant Reversal  Journal Articles
• Prothrombin complex concentrates versus fresh frozen plasma for warfarin reversal A systematic review and meta-analysis  Journal Articles
• Quality of Vitamin K Antagonist Control and 1-Year Outcomes in Patients with Atrial Fibrillation: A Global Perspective from the GARFIELD-AF Registry  Journal Articles
• Quality of anticoagulant control and patient experience associated with long-term warfarin in Canadian patients with non-valvular atrial fibrillation: A multicentre, prospective study  Journal Articles
• Quality of anticoagulation and use of warfarin-interacting medications in long-term care: A chart review  Journal Articles
• Quality of individual INR control and the risk of stroke and bleeding events in atrial fibrillation patients: A nested case control analysis of the ACTIVE W study  Journal Articles
• Randomised comparison of a simple warfarin dosing algorithm versus a computerised anticoagulation management system for control of warfarin maintenance therapy  Journal Articles
• Randomised, parallel-group, multicentre, multinational phase 2 study comparing edoxaban, an oral factor Xa inhibitor, with warfarin for stroke prevention in patients with atrial fibrillation  Journal Articles
• Randomized Trial of Warfarin Nomograms  Journal Articles
• Randomized Trial of Warfarin Nomograms  Journal Articles
• Randomized trial of warfarin nomograms.  Journal Articles
• Rapid diagnosis of coagulopathies from vitamin K deficiency in a consecutive case cohort evaluated by comparative assessment of factor II by one stage assays with prothrombin time versus Ecarin reagents  Journal Articles
• Rapid reversal of haematoma expansion associated with vitamin K antagonists  Journal Articles
• Recombinant FVIIa in children with liver disease  Journal Articles
• Reduced-dose warfarin or interrupted warfarin with heparin bridging for pacemaker or defibrillator implantation: A randomized trial  Journal Articles
• Reversal of the Anticoagulant Effects of Warfarin by Vitamin K1  Journal Articles
• Reversal of vitamin K antagonist-associated coagulopathy: A survey of current practice  Journal Articles
• Reversible endotension associated with excessive warfarin anticoagulation  Journal Articles
• Risk of post‐thrombotic syndrome after subtherapeutic warfarin anticoagulation for a first unprovoked deep vein thrombosis: results from the REVERSE study  Journal Articles
• Should vitamin K be administered when HIT is diagnosed after administration of coumarin?  Journal Articles
• Side-Effects of COVID-19 on Patient Care: An INR Story  Journal Articles
• Single-Arm Study of Bridging Therapy With Low-Molecular-Weight Heparin for Patients at Risk of Arterial Embolism Who Require Temporary Interruption of Warfarin  Journal Articles
• Single-dose adjustment versus no adjustment of warfarin in stably anticoagulated patients with an occasional international normalized ratio (INR) out of range  Journal Articles
• Small intestinal bacterial overgrowth and warfarin dose requirement variability  Journal Articles
• Solving the mystery of excessive warfarin-induced bleeding: A personal historical perspective  Journal Articles
• Stroke Prenotification Is Associated with Shorter Treatment Times for Warfarin-Associated Intracerebral Hemorrhage  Journal Articles
• Stroke and Bleeding Risk Co-distribution in Real-world Patients with Atrial Fibrillation: The Euro Heart Survey  Journal Articles
• Stroke prevention in atrial fibrillation: Closing the gap  Journal Articles
• Suboptimal effect of a three‐factor prothrombin complex concentrate (Profilnine‐SD) in correcting supratherapeutic international normalized ratio due to warfarin overdose  Journal Articles
• The Pharmacology and Management of the Vitamin K Antagonists  Journal Articles
• The Risk of Hemorrhage Among Patients With Warfarin-Associated Coagulopathy  Journal Articles
• The TRAAGIC score: early predictors of inpatient mortality in adult trauma patients  Journal Articles
• The Ten Most Commonly Asked Questions about Chronic Anticoagulant Use in Cardiology  Journal Articles
• The accuracy of the International Normalized Ratio and the American College of Chest Physicians recommendations on the use of vitamin K to reverse over-anticoagulation: a rebuttal  Journal Articles
• The effect of low-dose oral vitamin K supplementation on INR stability in patients receiving warfarin  Journal Articles
• The historical origins of modern international normalized ratio targets  Journal Articles
• The management of anticoagulated patients requiring dental extraction: a cross‐sectional survey of oral and maxillofacial surgeons and hematologists  Journal Articles
• Three Months versus One Year of Oral Anticoagulant Therapy for Idiopathic Deep Venous Thrombosis  Journal Articles
• Thromboembolic Consequences of Subtherapeutic Anticoagulation in Patients Stabilized on Warfarin Therapy: The Low INR Study  Conferences
• Time in therapeutic range: Warfarin anticoagulation for atrial fibrillation in a community-based practice.  Journal Articles
• Transesophageal echocardiography to guide cardioversion in patients with atrial fibrillation.  Journal Articles
• Transition from apixaban to warfarin—addressing excess stroke, systemic embolism, and major bleeding  Journal Articles
• Treatment and Prevention of Heparin-Induced Thrombocytopenia  Journal Articles
• Treatment of Warfarin-Associated Coagulopathy  Journal Articles
• Treatment of warfarin-associated coagulopathy with oral vitamin K: a randomised controlled trial  Journal Articles
• Treatment of warfarin-associated coagulopathy with vitamin K  Journal Articles
• Twelve‐month outcomes and predictors of very stable INR control in prevalent warfarin users  Journal Articles
• Underuse of evidence-based warfarin dosing methods for atrial fibrillation patients  Journal Articles
• Variation in Warfarin Dose Adjustment Practice Is Responsible for Differences in the Quality of Anticoagulation Control Between Centers and Countries  Journal Articles
• Venous limb gangrene during overlapping therapy with warfarin and a direct thrombin inhibitor for immune heparin‐induced thrombocytopenia  Journal Articles
• Venous thromboembolism and bleeding in critically ill patients with severe renal insufficiency receiving dalteparin prophylaxis: prevalence, incidence and risk factors  Journal Articles
• Vitamin K deficiency and D-dimer levels in the intensive care unit: a prospective cohort study  Journal Articles
• Vitamin K for reversal of excessive vitamin K antagonist anticoagulation: a systematic review and meta-analysis  Journal Articles
• Vitamin K in anticoagulation therapy  Journal Articles
• Vitamin K to reverse the anticoagulant effect of vitamin K antagonists: can you teach an old dog new tricks?  Journal Articles
• Vitamin K versus warfarin interruption alone in patients without bleeding and an international normalized ratio > 10  Journal Articles
• Warfarin Dose Assessment Every 4 Weeks Versus Every 12 Weeks in Patients With Stable International Normalized Ratios  Journal Articles
• Warfarin and acetaminophen interaction: a summary of the evidence and biologic plausibility  Journal Articles
• Warfarin-induced venous limb ischemia/gangrene complicating cancer: a novel and clinically distinct syndrome  Journal Articles
• Withdrawal of warfarin after deep vein thrombosis  Journal Articles