Clinical Trials, Phase III as Topic
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<p>Cost-Effectiveness Of Once-Daily Single-Inhaler Triple Therapy In COPD: The IMPACT Trial</p> Academic Article
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A critical appraisal of bleeding events reported in venous thromboembolism prevention trials of patients undergoing hip and knee arthroplasty Academic Article
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A multidisciplinary “think tank”: the top 10 clinical trial opportunities in transfusion medicine from the National Heart, Lung, and Blood Institute-sponsored 2009 state-of-the-science symposium Academic Article
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A systematic review of contemporary trials of anticoagulants in orthopaedic thromboprophylaxis: suggestions for a radical reappraisal Academic Article
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A tutorial on pilot studies: the what, why and how Academic Article
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Added value of health-related quality of life measurement in cancer clinical trials: the experience of the NCIC CTG Academic Article
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Alendronate for osteoporosis. Safe and efficacious nonhormonal therapy. Academic Article
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Analysis of Regional Timelines To Set Up a Global Phase III Clinical Trial in Breast Cancer: The Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization Experience Academic Article
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Andexanet alfa for the treatment of hemorrhage Academic Article
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Antacid therapy and disease outcomes in idiopathic pulmonary fibrosis: a pooled analysis Academic Article
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Association Between RECIST Changes and Survival in Patients with Metastatic Castration-resistant Prostate Cancer Receiving Docetaxel Academic Article
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Association of body weight with efficacy and safety outcomes in phase III randomized controlled trials of direct oral anticoagulants: a systematic review and meta‐analysis Academic Article
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Assumptions of Expected Benefits in Randomized Phase III Trials Evaluating Systemic Treatments for Cancer Academic Article
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Bivariate evaluation of thromboembolism and bleeding in clinical trials of anticoagulants in patients with atrial fibrillation Academic Article
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Bleeding Complications and Management on anticoagulant therapy Academic Article
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Bleeding with Direct Oral Anticoagulants vs Warfarin: Clinical Experience Academic Article
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Bleeding with direct oral anticoagulants vs warfarin: clinical experience Academic Article
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Bone Turnover Markers as Predictors of Skeletal Complications in Prostate Cancer, Lung Cancer, and Other Solid Tumors Academic Article
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Breaking the biomarker code: PD-L1 expression and checkpoint inhibition in advanced NSCLC Academic Article
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Burden of Proof for Tolvaptan in ADPKD Academic Article
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Cardiovascular Outcomes Trials in Type 2 Diabetes: Where Do We Go From Here? Reflections From aDiabetes CareEditors’ Expert Forum Academic Article
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Central Nervous System–Specific Outcomes of Phase 3 Randomized Clinical Trials in Patients With Advanced Breast Cancer, Lung Cancer, and Melanoma Academic Article
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Chemotherapy for advanced non-small-cell lung cancer: how much benefit is enough? Academic Article
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Clinical Experience With the New Oral Anticoagulants for Treatment of Venous Thromboembolism Academic Article
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Clinical data gap between phase III clinical trials (pre-marketing) and phase IV (post-marketing) studies: evaluation of etanercept in rheumatoid arthritis. Academic Article
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Clinical trial opportunities in hemostasis and thrombosis: NHBLI State-of-the-science symposium Academic Article
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Clinical trials of new anticoagulants. Academic Article
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Comparing mortality in patients with atrial fibrillation who are receiving a direct‐acting oral anticoagulant or warfarin: a meta‐analysis of randomized trials Academic Article
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Comparison of Outcomes of Phase II Studies and Subsequent Randomized Control Studies Using Identical Chemotherapeutic Regimens Conference Paper
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Complementary Medicine Use Amongst Patients with Metastatic Cancer Enrolled in Phase III Clinical Trials Academic Article
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Consistency of Phase III Clinical Trial Abstracts Presented at an Annual Meeting of the American Society of Clinical Oncology Compared With Their Subsequent Full-Text Publications Conference Paper
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Correlation of single arm versus randomised phase 2 oncology trial characteristics with phase 3 outcome Academic Article
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Cost-Effectiveness of Lanthanum Carbonate in the Treatment of Hyperphosphatemia in Dialysis Patients: A Canadian Payer Perspective Academic Article
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Dabigatran Etexilate: Future Directions in Anticoagulant Treatment Academic Article
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Dabigatran etexilate for prevention of venous thromboembolism Academic Article
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Dabigatran versus Warfarin for Acute Venous Thromboembolism in Elderly or Impaired Renal Function Patients: Pooled Analysis of RE-COVER and RE-COVER II. Academic Article
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Definition of clinically relevant non‐major bleeding in studies of anticoagulants in atrial fibrillation and venous thromboembolic disease in non‐surgical patients: communication from the SSC of the ISTH Academic Article
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Demographic, clinical, and patient-reported outcome data from 2 global, phase 3 trials of chronic cough Academic Article
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Design of the INPULSIS™ trials: Two phase 3 trials of nintedanib in patients with idiopathic pulmonary fibrosis Academic Article
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Direct oral anticoagulants compared with vitamin K antagonists for acute venous thromboembolism: evidence from phase 3 trials. Academic Article
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Direct-acting antiviral therapies for hepatitis C genotype 1 infection: a multiple treatment comparison meta-analysis Academic Article
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Do alternative methods of measuring tumor size, including consideration of multicentric/multifocal disease, enhance prognostic information beyond TNM staging in women with early stage breast cancer: an analysis of the NCIC CTG MA.5 and MA.12 clinical trials Academic Article
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Effect of Radiotherapy on Painful Bone Metastases Academic Article
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Effect of extended‐duration thromboprophylaxis on venous thromboembolism and major bleeding among acutely ill hospitalized medical patients: a bivariate analysis Academic Article
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Effect of visceral metastases on the efficacy and safety of everolimus in postmenopausal women with advanced breast cancer: Subgroup analysis from the BOLERO-2 study Academic Article
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Efficacy and safety of rolapitant for prevention of chemotherapy-induced nausea and vomiting over multiple cycles of moderately or highly emetogenic chemotherapy Academic Article
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Evaluation of metformin in early breast cancer: a modification of the traditional paradigm for clinical testing of anti-cancer agents Academic Article
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Exclusion of Patients With Brain Metastases in Published Phase III Clinical Trials for Advanced Breast Cancer Academic Article
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External applicability of the COMPASS trial: an analysis of the reduction of atherothrombosis for continued health (REACH) registry Academic Article
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Factor Xa inhibition in the prevention of venous thromboembolism and treatment of patients with venous thromboembolism Academic Article
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Factors that influence the recruitment of patients to Phase III studies in oncology Academic Article
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Fondaparinux Academic Article
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Fondaparinux, the first selective factor Xa inhibitor Academic Article
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Genome-Wide Associations and Functional Genomic Studies of Musculoskeletal Adverse Events in Women Receiving Aromatase Inhibitors Academic Article
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Genome-wide host methylation profiling of anal and cervical carcinoma Academic Article
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HER2 and TOP2A as predictive markers for anthracycline-containing chemotherapy regimens as adjuvant treatment of breast cancer: a meta-analysis of individual patient data Academic Article
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Identification of a Novel Hepatitis C Virus Genotype From Punjab, India: Expanding Classification of Hepatitis C Virus Into 8 Genotypes Academic Article
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Identification of prognostic factors in childhood T‐cell acute lymphoblastic leukemia: Results from DFCI ALL Consortium Protocols 05‐001 and 11‐001 Academic Article
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Impact of CYP19A1 and ESR1 variants on early-onset side effects during combined endocrine therapy in the TEXT trial Academic Article
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Impact of single-agent daily prednisone on outcomes in men with metastatic castration-resistant prostate cancer Academic Article
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Implementation of Timeline Reforms Speeds Initiation of National Cancer Institute-Sponsored Trials Academic Article
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Implications of variability in definition and reporting of major bleeding in randomized trials of oral P2Y12 inhibitors for acute coronary syndromes Academic Article
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Incidence of delayed venous thromboembolic events in patients undergoing abdominal and pelvic surgery for cancer: a systematic review and meta‐analysis Academic Article
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Incorporating edoxaban into the choice of anticoagulants for atrial fibrillation Academic Article
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Influence of an independent review committee on assessment of response rate and progression-free survival in phase III clinical trials Academic Article
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Influence of model-predicted rivaroxaban exposure and patient characteristics on efficacy and safety outcomes in patients with acute coronary syndrome Academic Article
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Integrated safety and efficacy analysis of once-daily fluticasone furoate for the treatment of asthma Academic Article
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Intraperitoneal chemotherapy in the first-line treatment of women with stage III epithelial ovarian cancer Academic Article
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Lessening Organ dysfunction with VITamin C (LOVIT): protocol for a randomized controlled trial Academic Article
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Magnitude of benefit of the addition of bevacizumab to first-line chemotherapy for metastatic colorectal cancer: meta-analysis of randomized clinical trials Conference Paper
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Major Bleeding, Mortality, and Efficacy of Fondaparinux in Venous Thromboembolism Prevention Trials Academic Article
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Management of Patients with Acute Coronary Syndromes Academic Article
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Mepitel Film and Mepilex Lite for the prophylaxis and treatment of skin toxicities from breast radiation Academic Article
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National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: VI. Design of Clinical Trials Working Group Report Academic Article
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New Anticoagulant Drugs Academic Article
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New Anticoagulants for Atrial Fibrillation Academic Article
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New Anticoagulants for Treatment of Venous Thromboembolism Academic Article
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New Antithrombotic Drugs Academic Article
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New Antithrombotic Drugs Academic Article
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New oral anticoagulant agents – general features and outcomes in subsets of patients Academic Article
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Optimizing the safety of treatment for venous thromboembolism in the era of the direct oral anticoagulants Academic Article
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Overstated Conclusions of a Pooled Analysis of Bevacizumab in Colon Cancer Academic Article
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Overview of the New Oral Anticoagulants Academic Article
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Overview of the clinical results of pentasaccharide in major orthopedic surgery. Academic Article
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PSMA PET/CT guided intensification of therapy in patients at risk of advanced prostate cancer (PATRON): a pragmatic phase III randomized controlled trial Academic Article
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Panorama From the Oncolytic Virotherapy Summit Academic Article
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Pentasaccharide Org31540/SR90107A clinical trials update: Lessons for practice Academic Article
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Phase 3 Trials of Stereotactic Radiosurgery With or Without Whole-Brain Radiation Therapy for 1 to 4 Brain Metastases: Individual Patient Data Meta-Analysis Academic Article
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Phosphoinositide 3-kinase inhibitors in advanced breast cancer: A systematic review and meta-analysis Academic Article
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Pointed Progress in Second-Line Advanced Non–Small-Cell Lung Cancer: The Rapidly Evolving Field of Checkpoint Inhibition Academic Article
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Posttreatment prognostic nomogram for patients with metastatic urothelial cancer completing first-line cisplatin-based chemotherapy Academic Article
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Potential net clinical benefit of population-wide implementation of apixaban and dabigatran among European patients with atrial fibrillation Academic Article
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Practical Understanding of Mean Percent Psoriasis Area and Severity Index Reduction for Biologics Academic Article
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Practical help for specifying the target difference in sample size calculations for RCTs: the DELTA2 five-stage study, including a workshop Academic Article
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Practical management of bleeding in patients receiving non-vitamin K antagonist oral anticoagulants Academic Article
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Predicting Anthracycline Benefit: TOP2A and CEP17—Not Only but Also Academic Article
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Profile of betrixaban and its potential in the prevention and treatment of venous thromboembolism Academic Article
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Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial Academic Article
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Proton Pump Inhibitors and Survival Outcomes in Patients With Metastatic Renal Cell Carcinoma Academic Article
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Proton pump inhibitors: the beginning of the end or the end of the beginning? Academic Article
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Quantitative evaluation of single-arm versus randomized phase II cancer clinical trials Academic Article
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Quizartinib for the treatment of acute myeloid leukemia Academic Article
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Randomized, controlled clinical trials in sepsis: Has methodological quality improved over time? Academic Article
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Rationale and design of the ATTRACT Study: A multicenter randomized trial to evaluate pharmacomechanical catheter-directed thrombolysis for the prevention of postthrombotic syndrome in patients with proximal deep vein thrombosis Academic Article
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Rationale, design and baseline characteristics of the effect of ticagrelor on health outcomes in diabetes mellitus patients Intervention study Academic Article
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Real-world vs. randomized trial outcomes in similar populations of rivaroxaban-treated patients with non-valvular atrial fibrillation in ROCKET AF and XANTUS Academic Article
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Refining risk classification in childhood B acute lymphoblastic leukemia: results of DFCI ALL Consortium Protocol 05-001 Academic Article
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Response of Primary Renal Cell Carcinoma to Systemic Therapy Academic Article
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Reversal of Direct Oral Anticoagulants: Current Status and Future Directions Academic Article
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Riociguat: A Novel Therapeutic Option for Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension Academic Article
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Rivaroxaban for the prevention and treatment of venous thromboembolism Academic Article
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Rivaroxaban for the prevention of venous thromboembolism after hip or knee arthroplasty Academic Article
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Rivaroxaban versus enoxaparin after total knee arthroplasty Academic Article
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Rolapitant for the treatment of chemotherapy-induced nausea and vomiting: a review of the clinical evidence Academic Article
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Role of Bone-Modifying Agents in Metastatic Breast Cancer: An American Society of Clinical Oncology–Cancer Care Ontario Focused Guideline Update Academic Article
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Role of new anticoagulants for the prevention of venous thromboembolism after major orthopaedic surgery and in hospitalised acutely ill medical patients Academic Article
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Safety Outcomes in Meta-analyses of Phase 2 vs Phase 3 Randomized Trials Academic Article
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Second-line or Subsequent Systemic Therapy for Recurrent or Progressive Non-Small Cell Lung Cancer: A Systematic Review and Practice Guideline Academic Article
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Second‐line treatment of hepatocellular carcinoma after sorafenib: Characterizing treatments used over the past 10 years and real‐world eligibility for cabozantinib, regorafenib, and ramucirumab Academic Article
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Seeking informed consent to cancer clinical trials: Academic Article
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Stereotactic ablative radiotherapy for the comprehensive treatment of 1–3 Oligometastatic tumors (SABR-COMET-3): study protocol for a randomized phase III trial Academic Article
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Systemic adjuvant therapy for adult patients at high risk for recurrent melanoma: A systematic review Academic Article
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TLE3 is not a predictive biomarker for taxane sensitivity in the NCIC CTG MA.21 clinical trial Academic Article
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Targeting Angiogenesis With Integrative Cancer Therapies Academic Article
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Taxanes as first-line therapy for advanced non-small cell lung cancer: A systematic review and practice guideline Academic Article
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The Advisory Committee on Immunization Practices’ Interim Recommendation for Use of Moderna COVID-19 Vaccine — United States, December 2020 Academic Article
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The Importance of Reporting Patient Recruitment Details in Phase III Trials Academic Article
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The SYGMA programme of phase 3 trials to evaluate the efficacy and safety of budesonide/formoterol given ‘as needed’ in mild asthma: study protocols for two randomised controlled trials Academic Article
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The association between radiographic response and overall survival in men with metastatic castration-resistant prostate cancer receiving chemotherapy Academic Article
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The effects of rivaroxaban on the complications of surgery after total hip or knee replacement Academic Article
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The unclear zone in phase II clinical trials Academic Article
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Thromboembolic events, recurrent bleeding and mortality after resuming anticoagulant following gastrointestinal bleeding Academic Article
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Thrombopoietin Receptor Agonists in Primary Immune Thrombocytopenia Academic Article
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Treatment Success in Cancer: Industry Compared to Publicly Sponsored Randomized Controlled Trials Academic Article
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Treatment-Dose LMWH versus Prophylactic/Intermediate Dose Heparins in High-Risk COVID-19 Inpatients: Rationale and Design of the HEP-COVID Trial Academic Article
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Trends in the application of dynamic allocation methods in multi-arm cancer clinical trials Academic Article
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Use of Adjuvant Bisphosphonates and Other Bone-Modifying Agents in Breast Cancer: ASCO-OH (CCO) Guideline Update Academic Article
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Users’ guide to the surgical literature: how to assess an article using surrogate end points Academic Article
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Validation of the Association of RECIST Changes With Survival in Men With Metastatic Castration-Resistant Prostate Cancer Treated on SWOG Study S0421 Academic Article
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Venous thromboembolism prophylaxis: role of factor xa inhibition by fondaparinux. Academic Article
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What's New in Stroke? Phase III Randomized Clinical Trials of 2012–2014 Academic Article
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When is it safe to stop for safety? Academic Article
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Workshop on Partial Breast Irradiation: State of the Art and the Science, Bethesda, MD, December 8-10, 2002 Academic Article