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Impact of single-agent daily prednisone on...
Journal article

Impact of single-agent daily prednisone on outcomes in men with metastatic castration-resistant prostate cancer

Abstract

Background:Despite palliative benefits and PSA responses, the objective clinical impact of daily oral prednisone (P) for metastatic castration-resistant prostate cancer (mCRPC) is unknown. We performed a pooled analysis of control arms of randomized trials that either did or did not administer single-agent P to evaluate its impact on overall survival (OS) and toxicities.Methods:Individual patient data from control arms of randomized trials of …

Authors

Sonpavde G; Pond GR; Templeton AJ; Kwon ED; De Bono JS

Journal

Prostate Cancer and Prostatic Diseases, Vol. 20, No. 1, pp. 67–71

Publisher

Springer Nature

Publication Date

3 2017

DOI

10.1038/pcan.2016.44

ISSN

1365-7852