Mepitel Film and Mepilex Lite for the prophylaxis and treatment of skin toxicities from breast radiation Academic Article uri icon

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abstract

  • Despite the prevalence of radiation dermatitis in breast cancer patients, current practice guidelines for its treatment are limited. We aimed to discuss the quality of evidence for the barrier-forming Mepitel Film for prophylaxis of radiation dermatitis, and argue for further investigation into evidence-based management of skin toxicities. Two studies assessing Mepitel Film were critically evaluated. Both reported that Mepitel Film decreased radiation dermatitis; moreover, patient-reported outcomes significantly favoured Mepitel Film. However, there has not been global adoption of barrier-forming films such as Mepitel, in part due to the absence of multi-centred randomised trials and the heterogeneity of study designs.

authors

  • Wan, Bo Angela
  • Chan, Stephanie
  • Herst, Patries
  • Yee, Caitlin
  • Popovic, Marko
  • Lee, Justin
  • Lam, Henry
  • Pon, Kucy
  • Aljabri, Saleh
  • Soliman, Hany
  • Wronski, Matt
  • Chow, Edward

publication date

  • August 2019

published in