Alimentary Pharmacology and Therapeutics
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Overview
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Editorial: methotrexate in patients with Crohn's disease refractory to anti-TNF therapy-moving backwards yet forward?.
53:950-951.
2021
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Derivation and validation of a novel method to subgroup patients with functional dyspepsia: beyond upper gastrointestinal symptoms..
53:253-264.
2021
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Editorial: acid suppression with potassium-competitive acid blockers dismissing genotype concerns..
53:187-188.
2021
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Systematic review and network meta-analysis: efficacy of drugs for functional dyspepsia.
53:8-21.
2021
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Letter: mesalazine-a safe drug with rare serious adverse events? Authors’ reply.
51:1212-1212.
2020
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Letter: corticosteroid use alongside tofacitinib in OCTAVE Open. Authors' reply.
51:997-998.
2020
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Prevalence of endoscopic improvement and remission according to patient-reported outcomes in ulcerative colitis.
51:435-445.
2020
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Efficacy and safety of tofacitinib dose de-escalation and dose escalation for patients with ulcerative colitis: results from OCTAVE Open.
51:271-280.
2020
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Editorial: potassium-competitive acid blockers for acid-related diseases-tegoprazan, a new kid on the block.
50:960-962.
2019
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Editorial: the overlap between dyspepsia and gastro-oesophageal reflux-is duodenal eosinophilia the missing link?.
50:454-455.
2019
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Systematic review with meta-analysis: association betweenHelicobacter pyloriCagA seropositivity and odds of inflammatory bowel disease.
50:121-131.
2019
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Letter: meta-analysis of prebiotics, probiotics, synbiotics and antibiotics in IBS. Authors’ reply.
49:1254-1255.
2019
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Editorial: metabolomic biomarkers for colorectal adenocarcinoma and in the differentiation between irritable bowel syndrome and ulcerative colitis in clinical remission - confounded by the gut microbiome? Authors’ reply.
49:1088-1089.
2019
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Comparison of the metabolomic profiles of irritable bowel syndrome patients with ulcerative colitis patients and healthy controls: new insights into pathophysiology and potential biomarkers.
49:723-732.
2019
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Editorial: ulcer-related vs non-ulcer-nonvariceal upper gastrointestinal bleeding-which has worse outcomes?.
49:818-819.
2019
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Systematic review with meta-analysis: the efficacy of prebiotics, probiotics, synbiotics and antibiotics in irritable bowel syndrome.
48:1044-1060.
2018
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Systematic review: safety of mesalazine in ulcerative colitis.
47:1597-1609.
2018
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Editorial: the prevalence of Helicobacter pylori
infection worldwide-knowns and unknowns.
47:1330-1331.
2018
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The use of selective serotonin receptor inhibitors (SSRIs) is not associated with increased risk of endoscopy-refractory bleeding, rebleeding or mortality in peptic ulcer bleeding.
46:355-363.
2017
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Systematic review with meta-analysis: proximal disease extension in limited ulcerative colitis.
45:1481-1492.
2017
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Editorial: latent class analysis to improve confidence in the diagnosis of IBS - authors’ reply.
45:1268-1269.
2017
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Letter: NICE referral criteria for lower gastrointestinal alarm features - not ideal but not poor either. Authors' reply.
45:1176-1176.
2017
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Derivation and validation of a diagnostic test for irritable bowel syndrome using latent class analysis.
45:824-832.
2017
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Review article: dose optimisation of infliximab for acute severe ulcerative colitis.
45:617-630.
2017
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Poor predictive value of lower gastrointestinal alarm features in the diagnosis of colorectal cancer in 1981 patients in secondary care.
45:91-99.
2017
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Letter: comparative safety and efficacy of infliximab vs. adalimumab in Crohn's disease - should one consider disease location? Authors’ reply.
44:772-773.
2016
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An index with improved diagnostic accuracy for the diagnosis of Crohn's disease derived from the Lennard-Jones criteria.
44:601-611.
2016
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The efficacy and safety of either infliximab or adalimumab in 362 patients with anti-TNF-α naïve Crohn's disease.
44:170-180.
2016
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Letter: mucosal healing is associated with improved long-term outcomes in Crohn's disease - authors' reply.
43:1347-1348.
2016
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Systematic review with meta-analysis: mucosal healing is associated with improved long-term outcomes in Crohn's disease.
43:317-333.
2016
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Editorial: towards extended acid suppression - the search continues.
42:1027-1029.
2015
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Irritable bowel syndrome is significantly associated with somatisation in 840 patients, which may drive bloating.
41:449-458.
2015
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Editorial: healing of refractory reflux oesophagitis - an ongoing unmet clinical need.
40:987-989.
2014
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A prospective cohort study to determine the relationship between serum infliximab concentration and efficacy in patients with luminal Crohn's disease.
39:1126-1135.
2014
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Commentary: independent risk factors for recurrent neoplasia after endoscopic resection of early gastric cancer.
39:993-994.
2014
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Characteristics of functional bowel disorder patients: a cross-sectional survey using the Rome III criteria.
39:312-321.
2014
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Meta-analysis: rectal indomethacin for the prevention of post-ERCP pancreatitis.
38:995-1001.
2013
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Review article: a clinician's guide for therapeutic drug monitoring of infliximab in inflammatory bowel disease.
38:447-459.
2013
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Meta-analysis: peri-operative anti-TNFα treatment and post-operative complications in patients with inflammatory bowel disease.
37:1057-1064.
2013
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Meta-analysis: colonoscopic post-polypectomy bleeding in patients on continued clopidogrel therapy.
37:947-952.
2013
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The impact of intensifying acid suppression on sleep disturbance related to gastro-oesophageal reflux disease in primary care.
37:730-737.
2013
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The natural history of gastro-oesophageal reflux symptoms in the community and its effects on survival: a longitudinal 10-year follow-up study.
37:323-331.
2013
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Review article: current treatment options and management of functional dyspepsia.
36:3-15.
2012
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Commentary: what is the optimal PPI dosing following endoscopic haemostasis in acute ulcer bleeding?.
35:1351-1352.
2012
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Randomised clinical trial: the safety and efficacy of long-acting octreotide in patients with portal hypertension.
35:904-912.
2012
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PPI co-therapy did not adversely affect outcomes in clopidogrel users.
35:313-314.
2012
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Sequential therapy - more studies are still required.
35:194-195.
2012
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Mesalazine (5-aminosalicylic acid) alters faecal bacterial profiles, but not mucosal proteolytic activity in diarrhoea-predominant irritable bowel syndrome.
34:374-383.
2011
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Night-time intra-oesophageal bile and acid exposure in GERD patients failing PPI therapy.
33:1068-1069.
2011
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Rabeprazole extended-release 50 mg compared with esomeprazole 40 mg and rabeprazole delayed release 20 mg.
33:1177-1179.
2011
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Meta-analysis: factors affecting placebo response rate in the irritable bowel syndrome.
32:144-158.
2010
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Cost-utility analysis of proton pump inhibitors and other gastro-protective agents for prevention of gastrointestinal complications in elderly patients taking nonselective nonsteroidal anti-inflammatory agents.
31:1354-1364.
2010
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Meta-analysis: proton pump inhibitor use and the risk of community-acquired pneumonia.
31:1165-1177.
2010
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The development and validation of a new coeliac disease quality of life survey (CD-QOL).
31:666-675.
2010
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The pharmacodynamics and pharmacokinetics of S-tenatoprazole-Na 30 mg, 60 mg and 90 mg vs. esomeprazole 40 mg in healthy male subjects.
31:648-657.
2010
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Inaccurate endoscopy: a better explanation for placebo-associated endoscopic ulcers: authors’ reply.
30:957-960.
2009
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Meta-analysis: incidence of endoscopic gastric and duodenal ulcers in placebo arms of randomized placebo-controlled NSAID trials.
30:197-209.
2009
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10-biomarker algorithm to identify irritable bowel syndrome.
30:95-96.
2009
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Glucocorticoids can help in acute severe alcoholic hepatitis: authors’ reply.
30:93-95.
2009
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Meta-analysis: yield of diagnostic tests for coeliac disease in dyspepsia.
30:28-36.
2009
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Clinical trial: factors associated with freedom from relapse of heartburn in patients with healed reflux oesophagitis - results from the maintenance phase of the EXPO study.
29:1165-1171.
2009
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Clinical trial: factors associated with resolution of heartburn in patients with reflux oesophagitis - results from the EXPO study.
29:959-966.
2009
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Canadian consensus guidelines on long-term nonsteroidal anti-inflammatory drug therapy and the need for gastroprotection: benefits versus risks.
29:481-496.
2009
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Fluctuation of gastrointestinal symptoms in the community: a 10-year longitudinal follow-up study.
28:1013-1020.
2008
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Meta-analysis:Helicobacter pylori‘test and treat’ compared with empirical acid suppression for managing dyspepsia.
28:534-544.
2008
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Clinical trial design in adult reflux disease: a methodological workshop.
28:107-126.
2008
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Clinical trial: exposure to ribavirin predicts EVR and SVR in patients with HCV genotype 1 infection treated with peginterferon alfa-2a plus ribavirin.
28:43-50.
2008
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Predictable prolonged suppression of gastric acidity with a novel proton pump inhibitor, AGN 201904-Z.
28:187-199.
2008
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Systematic review: persistence and severity in gastroesophageal reflux disease.
28:841-853.
2008
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Systematic review: glucocorticosteroids for alcoholic hepatitis - a Cochrane Hepato-Biliary Group systematic review with meta-analyses and trial sequential analyses of randomized clinical trials.
27:1167-1178.
2008
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Mortality risks associated with Barrett’s oesophagus: authors' reply.
27:853-854.
2008
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Mortality rates in patients with Barrett’s oesophagus.
27:316-320.
2008
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New algorithm for the treatment of gastro-oesophageal reflux disease.
27:249-256.
2008
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Clinical trial: knowledge of negative Helicobacter pylori status reduces subsequent dyspepsia-related resource use.
26:1267-1275.
2007
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Meta-analysis: the use of non-steroidal anti-inflammatory drugs and pancreatic cancer risk for different exposure categories.
26:1089-1099.
2007
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Systematic review and meta-analysis: the incidence and prognosis of post-infectious irritable bowel syndrome.
26:535-544.
2007
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Overlap of gastro-oesophageal reflux disease and irritable bowel syndrome: prevalence and risk factors in the general population.
26:453-461.
2007
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Symptom overlap in patients with upper gastrointestinal complaints in the Canadian confirmatory acid suppression test (CAST) study: further psychometric validation of the reflux disease questionnaire.
25:1087-1097.
2007
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GI Epidemiology: infection epidemiology and acute gastrointestinal infections.
25:669-674.
2007
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Meta-analysis: Helicobacter pylori eradication treatment efficacy in children.
25:523-536.
2007
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The Short-Form Leeds Dyspepsia Questionnaire validation study.
25:477-486.
2007
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Oral rabeprazole vs. intravenous pantoprazole: a comparison of the effect on intragastric pH in healthy subjects.
0:061116055830001-???.
2007
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Injection of botulinum toxin before pneumatic dilatation in achalasia treatment: a randomized-controlled trial.
24:983-989.
2006
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Predictors of treatment response in patients with non-erosive reflux disease.
24:371-376.
2006
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Healing rates for moderate and severe oesophagitis: author's reply.
23:1374-1375.
2006
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Levofloxacin-based rescue regimens after Helicobacter pylori treatment failure: how strong is the evidence?.
23:1283-1285.
2006
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The prevalence of Barrett's oesophagus in a cohort of 1040 Canadian primary care patients with uninvestigated dyspepsia undergoing prompt endoscopy.
23:595-599.
2006
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Errata.
23:449-449.
2006
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Validation of a 7-point Global Overall Symptom scale to measure the severity of dyspepsia symptoms in clinical trials.
23:521-529.
2006
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Validation of a symptom diary for patients with gastro-oesophageal reflux disease.
23:531-541.
2006
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Review article: the unmet needs in delayed-release proton-pump inhibitor therapy in 2005.
22:10-19.
2005
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Esomeprazole 20 mg vs. pantoprazole 20 mg for maintenance therapy of healed erosive oesophagitis: results from the EXPO study1.
22:803-811.
2005
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Proton-pump inhibitor for peptic ulcer bleeding: Authors' reply.
22:892-892.
2005
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Lower oesophageal sphincter pressure and timed barium oesophagogram: two objective parameters in the non-invasive assessment of primary achalasia.
22:261-265.
2005
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Review article: gastro-oesophageal reflux disease - the extent of the problem.
22:11-19.
2005
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Systematic review and meta-analysis: proton-pump inhibitor treatment for ulcer bleeding reduces transfusion requirements and hospital stay - results from the Cochrane Collaboration.
22:169-174.
2005
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Gastro-oesophageal reflux is more prevalent in Western dyspeptics: a prospective comparison of British and South-East Asian patients with dyspepsia.
21:1483-1490.
2005
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Heartburn-dominant, uninvestigated dyspepsia: a comparison of 'PPI-start' and 'H2-RA-start' management strategies in primary care - the CADET-HR Study.
21:1189-1202.
2005
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Managing dyspepsia without alarm signs in primary care: new national guidance for England and Wales.
21:1135-1143.
2005
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Systematic review and meta-analysis: enhanced efficacy of proton-pump inhibitor therapy for peptic ulcer bleeding in Asia - a post hoc analysis from the Cochrane Collaboration.
21:1055-1061.
2005
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A randomized comparative study of esomeprazole 40 mg versus pantoprazole 40 mg for healing erosive oesophagitis: the EXPO study.
21:739-746.
2005
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Intestinal permeability in patients with irritable bowel syndrome after a waterborne outbreak of acute gastroenteritis in Walkerton, Ontario.
20:1317-1322.
2004
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Do physicians correctly assess patient symptom severity in gastro-oesophageal reflux disease?.
20:1161-1169.
2004
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International validation of ReQuest in patients with endoscopy-negative gastro-oesophageal reflux disease.
20:891-898.
2004
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Review article: gastric pH - the most relevant predictor of benefit in reflux disease?.
20:19-26.
2004
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Review article: towards consistency in the endoscopic diagnosis of Barrett's oesophagus and columnar metaplasia.
20:40-47.
2004
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Corrigenda.
20:702-702.
2004
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Pneumatic balloon dilatation in achalasia: a prospective comparison of safety and efficacy with different balloon diameters.
20:431-436.
2004
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Do we need a new gastro-oesophageal reflux disease questionnaire?.
19:463-479.
2004
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The methodological quality of trials affects estimates of treatment efficacy in functional (non-ulcer) dyspepsia.
19:631-641.
2004
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Economic evaluation of Helicobacter pylori eradication in the CADET-Hp randomized controlled trial of H. pylori-positive primary care patients with uninvestigated dyspepsia.
19:349-358.
2004
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Should NSAID/low-dose aspirin takers be tested routinely for H. pylori
infection and treated if positive? Implications for primary risk of ulcer and ulcer relapse after initial healing.
19:9-16.
2004
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Uninvestigated dyspepsia and non-ulcer dyspepsia-the use of endoscopy and the roles of Helicobacter pylori
eradication and antisecretory therapy.
19:1-8.
2004
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Impact of functional gastrointestinal disorders on health-related quality of life: a population-based case-control study.
19:233-242.
2004
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Oral esomeprazole vs. intravenous pantoprazole: a comparison of the effect on intragastric pH in healthy subjects.
18:705-711.
2003
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Oral esomeprazole vs. intravenous pantoprazole: a comparison of the effect on intragastric pH in healthy subjects.
18:705-711.
2003
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The prevalence of clinically significant endoscopic findings in primary care patients with uninvestigated dyspepsia: the Canadian Adult Dyspepsia Empiric Treatment - Prompt Endoscopy (CADET-PE) study.
17:1481-1491.
2003
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Mycophenolate mofetil in refractory inflammatory bowel disease.
17:1365-1369.
2003
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The prevalence of clinically significant endoscopic findings in primary care patients with uninvestigated dyspepsia: the Canadian Adult Dyspepsia Empiric Treatment - Prompt Endoscopy (CADET-PE) study.
17:1481-1491.
2003
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Systematic review: antacids, H2
-receptor antagonists, prokinetics, bismuth and sucralfate therapy for non-ulcer dyspepsia.
17:1215-1227.
2003
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Complementary studies of the gastrointestinal safety of the cyclo-oxygenase-2-selective inhibitor etoricoxib.
17:201-210.
2003
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Complementary studies of the gastrointestinal safety of the cyclo-oxygenase-2-selective inhibitor etoricoxib.
17:201-210.
2003
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Acid suppression in healthy subjects following lansoprazole or pantoprazole.
16:425-433.
2002
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The cost-effectiveness of population Helicobacter pylori
screening and treatment: a Markov model using economic data from a randomized controlled trial.
16:559-568.
2002
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Current concepts in the management of Helicobacter pylori
infection-The Maastricht 2-2000 Consensus Report.
16:167-180.
2002
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Randomized controlled trial comparing botulinum toxin injection to pneumatic dilatation for the treatment of achalasia.
15:1389-1396.
2001
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Review article: should we kill or should we save Helicobacter pylori
?.
15:51-59.
2001
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Duration of effect of lansoprazole on gastric pH and acid secretion in normal male volunteers.
15:105-113.
2001
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A randomized controlled trial to assess alendronate-associated injury of the upper gastrointestinal tract.
14:1451-1457.
2000
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Helicobacter pylori and gastric cancer − the clinicians' point of view.
14:48-54.
2000
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The effectiveness of omeprazole, clarithromycin and tinidazole in eradicating Helicobacter pylori
in a community screen and treat programme.
14:719-728.
2000
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The effects of omeprazole on healing and appearance of small gastric and duodenal lesions during dosing with diclofenac in healthy subjects.
14:535-541.
2000
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Lack of a pharmacokinetic interaction between lansoprazole or pantoprazole and theophylline.
14:345-352.
2000
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The importance of clarithromycin dose in the management of H. pylori
infection: a meta-analysis of triple therapies with a proton pump inhibitor, clarithromycin and amoxycillin or metronidazole.
13:1693-1693.
1999
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5-Day H. pylori
eradication.
13:1252-1252.
1999
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Reply - 5-Day H. pylori
eradication.
13:1253-1253.
1999
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The importance of clarithromycin dose in the management ofHelicobacter pyloriinfection: a meta-analysis of triple therapies with a proton pump inhibitor, clarithromycin and amoxycillin or metronidazole.
13:719-729.
1999
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Anti-ulcerogenic properties of endothelin receptor antagonists in the rat.
13:537-544.
1999
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The optimal antibiotic combination in a 5-day Helicobacter pylori
eradication regimen.
13:497-501.
1999
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Clarithromycin-based triple therapies.
13:437-438.
1999
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Effects of pumaprazole (BY841), a novel reversible proton pump antagonist, and of omeprazole, on intragastric acidity before and after cure of Helicobacter pylori
infection.
13:27-34.
1999
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Olestra and its gastrointestinal safety.
12:1185-1200.
1998
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Review article: olestra and its gastrointestinal safety.
12:1185-1200.
1998
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The Leeds Dyspepsia Questionnaire: a valid tool for measuring the presence and severity of dyspepsia.
12:1257-1262.
1998
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Dose-response relationship of lansoprazole to gastric acid antisecretory effects.
12:321-327.
1998
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Letters to the Editors.
12:395-396.
1998
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Clinical economics review: cost-effectiveness of treatment alternatives for gastro-oesophageal reflux disease.
10:865-873.
1996
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Time to maximum effect of lansoprazole on gastric pH in normal male volunteers.
10:897-904.
1996
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Effects of misoprostol on healing and prevention of biopsy-induced gastroduodenal lesions occurring during the administration of diclofenac to volunteers.
10:563-569.
1996
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Erratum: Effects of misoprostol on healing and prevention of biopsy-induced gastroduodenal lesions occurring during the administration of diclofenac to volunteers.
10:833.
1996
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The efect of indornethacin-induced gastric rnucosal injury on 24-h intragastric acidity and plasma gastrin concentration in healthy volunteers.
9:625-631.
1995
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Rectal aminosalicylate therapy for distal ulcerative colitis: a meta-analysis.
9:293-300.
1995
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The relationship between the control of pH and healing and symptom relief in gastro-oesophageal reflux disease.
9:3-7.
1995
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The rationale of acid suppression in the treatment of acid-related disease..
8:3-10.
1994
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Omeprazole (20 mg) daily given in the morning or evening: a comparison of effects on gastric acidity, and plasma gastrin and omeprazole concentration.
6:103-111.
1992
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Twenty-four-hour intragastric acidity and nocturnal gastric secretion in gastric ulcer patients-the effects of cimetidine.
4:275-281.
1990
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The relationship between suppression of acidity and gastric ulcer healing rates.
4:25-33.
1990
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Does misoprostol given as a single large dose improve its antisecretory effect?.
3:403-407.
1989
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The effect of tripotassium dicitrato bismuthate on pepsin activity.
3:381-385.
1989
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Twenty-four-hour intragastric measurements in twenty healthy subjects: effect of enisoprost, a novel and potent antisecretory and antipeptic synthetic E1 prostaglandin.
2:325-336.
1988
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Marked suppression of stimulated gastric acid and pepsin secretion by enisoprost, a new PGE1 analogue.
1:305-313.
1987
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The effects of intravenous famotidine on pentagastrin-stimulated gastric secretion in man.
1:125-132.
1987
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Histologic remission does not offer additional benefit for ulcerative colitis patients in endoscopic remission.
2020
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Systematic review with meta-analysis: enteral nutrition therapy for the induction of remission in paediatric Crohn's disease
2017
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Airway inflammation and asthma.
1996
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