Journal article
Validation of a symptom diary for patients with gastro‐oesophageal reflux disease
Abstract
BACKGROUND: Symptom diaries are potentially attractive but, because of concerns about patient compliance, they have had limited use in clinical trials. We assessed the validity and responsiveness of a symptom diary for patients with gastro-oesophageal reflux disease.
METHODS: We included 215 patients with gastro-oesophageal reflux disease after starting treatment for 4 weeks with 40 mg esomeprazole once daily. Patients recorded whether they …
Authors
PUHAN MA; GUYATT GH; ARMSTRONG D; WIKLUND I; FALLONE CA; HEELS‐ANSDELL D; DEGL'INNOCENTI A; VAN ZANTEN SJOV; TANSER L; BARKUN AN
Journal
Alimentary Pharmacology & Therapeutics, Vol. 23, No. 4, pp. 531–541
Publisher
Wiley
Publication Date
February 2006
DOI
10.1111/j.1365-2036.2006.02775.x
ISSN
0269-2813