The effect of tripotassium dicitrato bismuthate on pepsin activity Journal Articles

abstract

• SUMMARYWe have studied the effect of tripotassium dicitrato bismuthate on the peptic activity of gastric juice, both basal and pentagastrin‐stimulated, from five healthy volunteers using porcine pepsin solution as a control. Tripotassium dicitrato bismuthate showed no inhibition of the proteolytic activity of either the pure porcine or the human pepsin in the gastric juice. The ulcer healing efficacy of tripotassium dicitrato bismuthate is unlikely to be related to a gastric anti‐protease effect.

authors

• DE BEAUX, AC
• DEFIZE, J
• Hunt, Richard H

status

• published 

publication date

• August 1989

has subject area

• 1103 Clinical Sciences (FoR)
• 1115 Pharmacology and Pharmaceutical Sciences (FoR)
• Animals (MeSH)
• Anti-Ulcer Agents (MeSH)
• Gastric Juice (MeSH)
• Gastroenterology & Hepatology (Science Metrix)
• Humans (MeSH)
• Organometallic Compounds (MeSH)
• Pepsin A (MeSH)
• Protease Inhibitors (MeSH)
• Swine (MeSH)

published in

• Alimentary Pharmacology and Therapeutics  Journal

keywords

• Animals
• Anti-Ulcer Agents
• Gastric Juice
• Humans
• Organometallic Compounds
• Pepsin A
• Protease Inhibitors
• Swine

Digital Object Identifier (DOI)

• 10.1111/j.1365-2036.1989.tb00225.x

PubMed ID

• 2518852

start page

• 381

end page

• 385

volume

• 3

issue

• 4