selected scholarly activity
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books
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conferences
- In Utero Exposure to Ionizing Radiation and the Respiratory Response to an Acute Lung Injury Stimulus at Adolescence. American Journal of Respiratory and Critical Care Medicine. 2019
- The Heat Shock Response of Round Whitefish. Integrative and Comparative Biology. E117-E117. 2017
- Daily, Incremental Changes in Incubation Temperature Alter Metabolism and Hatchling Phenotype of Developing Lake Whitefish. The FASEB Journal. 2016
- Hatchling Phenotype Of Lake Whitefish Incubated At Increased Temperature During Critical Windows Of Development. The FASEB Journal. 2016
- Degraded DNA and next-generation sequencing: low quality DNA affects double digest restriction associated DNA sequencing. Genome. 390-390. 2014
- Limited impact of phlebotomy technique on proteomic measures. Genome. 391-392. 2014
- Pantomic studies in environmental toxicology answers, questions and extrapolation. Journal of Experimental Zoology Part A: Ecological and Integrative Physiology. 181-181. 2006
- Patterns of cyp1a induction in endothelial cells cultured from the eel, Anguilla rostrata and the bottlenose dolphin, Tursiops truncatus. Marine Environmental Research. S62-S62. 2006
- Cytochrome P450 1A and related measurements in juvenile chinook salmon (<i>Oncorhynchus tshawytscha</i>) from the Fraser River. Canadian Journal of Fisheries and Aquatic Sciences. 405-413. 2000
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journal articles
- Embryonic and larval development of yellow perch (Perca flavescens) and its sensitivity to incubation temperature. Journal of Fish Biology. 105:735-751. 2024
- Is there potential for estradiol receptor signaling in lophotrochozoans?. General and Comparative Endocrinology. 354:114519-114519. 2024
- Effects of metformin on wild fathead minnows (Pimephales promelas) using in-lake mesocosms in a boreal lake ecosystem. Science of the Total Environment. 929:172457-172457. 2024
- Absence of Depressive and Anxious Behavior with Genetic Dysregulation in Adult C57Bl/6J Mice after Prenatal Exposure to Ionizing Radiation. International Journal of Molecular Sciences. 24:8466-8466. 2023
- Effect of elevated embryonic incubation temperature on the temperature preference of juvenile lake (Coregonus clupeaformis) and round whitefish (Prosopium cylindraceum). Conservation Physiology. 11. 2023
- Thermal acclimation alters both basal heat shock protein gene expression and the heat shock response in juvenile lake whitefish (Coregonus clupeaformis). Journal of Thermal Biology. 104:103185-103185. 2022
- Population structure of lake whitefish (Coregonus clupeaformis) from the Mississippian lineage in North America. Facets. 7:853-874. 2022
- The gut content microbiome of wild-caught rainbow darter is altered during laboratory acclimation. Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics. 39:100835-100835. 2021
- The heat shock response shows plasticity in embryonic lake whitefish (Coregonus clupeaformis) exposed to repeated thermal stress. Journal of Thermal Biology. 100:103036-103036. 2021
- Evaluating tank acclimation and trial length for dynamic shuttle box temperature preference assays in aquatic animals. Journal of Experimental Biology. 224. 2021
- Evaluating tank acclimation and trial length for dynamic shuttle box temperature preference assays in aquatic animals.. Journal of Experimental Biology. 224:jeb233205. 2021
- Lasting Effects of Low to Non-Lethal Radiation Exposure during Late Gestation on Offspring’s Cardiac Metabolism and Oxidative Stress. Antioxidants. 10:816-816. 2021
- The cytochrome P450 (CYP) superfamily in cnidarians. Scientific Reports. 11:9834. 2021
- A model to predict embryonic development and hatching in lake whitefish (Coregonus clupeaformis) under variable incubation temperatures. Journal of Great Lakes Research. 47:494-503. 2021
- Unchanged cardiovascular and respiratory outcomes in healthy C57Bl/6 mice after in utero exposure to ionizing radiation. International Journal of Radiation Biology. 97:131-138. 2021
- A screen of kinase inhibitors reveals a potential role of Chk1 in regulating Hydra head regeneration and maintenance. International Journal of Developmental Biology. 65:523-536. 2021
- Rainbow darter (Etheostoma caeruleum) from a river impacted by municipal wastewater effluents have altered gut content microbiomes. Science of the Total Environment. 751:141724-141724. 2021
- The round goby genome provides insights into mechanisms that may facilitate biological invasions. Journal of Biology. 18:11. 2020
- Prostaglandins prevent acetaminophen induced embryo toxicity in zebrafish (Danio rerio). Environmental Toxicology and Pharmacology. 80:103463-103463. 2020
- Chronic exposure of Brown (Hydra oligactis) and green Hydra (Hydra viridissima) to environmentally relevant concentrations of pharmaceuticals. Science of the Total Environment. 732:139232-139232. 2020
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Modifying effects of a cobble substrate on thermal environments and implications for embryonic development in lake whitefish (
Coregonus clupeaformis ). Journal of Fish Biology. 97:113-120. 2020 - Zebrafish CYP1A expression in transgenic Caenorhabditis elegans protects from exposures to benzo[a]pyrene and a complex polycyclic aromatic hydrocarbon mixture. Toxicology. 440:152473-152473. 2020
- How “simple” methodological decisions affect interpretation of population structure based on reduced representation library DNA sequencing: A case study using the lake whitefish. PLoS ONE. 15:e0226608-e0226608. 2020
- Paternal Exposure to Carbamazepine Impacts Zebrafish Offspring Reproduction Over Multiple Generations. Environmental Science and Technology. 53:12734-12743. 2019
- Thermal dependence of size-at-hatch in the lake whitefish (Coregonus clupeaformis). Canadian Journal of Fisheries and Aquatic Sciences. 76:2069-2079. 2019
- Cardiovascular and growth outcomes of C57Bl/6J mice offspring exposed to maternal stress and ionizing radiation during pregnancy. International Journal of Radiation Biology. 95:1085-1093. 2019
- Parental gemfibrozil exposure impacts zebrafish F1 offspring, but not subsequent generations. Aquatic Toxicology. 212:194-204. 2019
- Waterborne pharmaceutical uptake and toxicity is modified by pH and dissolved organic carbon in zebrafish. Aquatic Toxicology. 210:11-18. 2019
- CYP3C gene regulation by the aryl hydrocarbon and estrogen receptors in zebrafish. Toxicology and Applied Pharmacology. 362:77-85. 2019
- Daily, repeating fluctuations in embryonic incubation temperature alter metabolism and growth of Lake whitefish (Coregonus clupeaformis). Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 226:49-56. 2018
- DNA barcoding vs. morphological identification of larval fish and embryos in Lake Huron: Advantages to a molecular approach. Journal of Great Lakes Research. 44:1110-1116. 2018
- Impacts of temperature, morpholine, and chronic radiation on the embryonic development of round whitefish (Prosopium cylindraceum). Environmental Toxicology and Chemistry. 37:2593-2608. 2018
- Genetic population structure of the round whitefish (Prosopium cylindraceum) in North America: multiple markers reveal glacial refugia and regional subdivision. Canadian Journal of Fisheries and Aquatic Sciences. 75:836-849. 2018
- The effects of parental carbamazepine and gemfibrozil exposure on sexual differentiation in zebrafish (Danio rerio). Environmental Toxicology and Chemistry. 37:1696-1706. 2018
- Gemfibrozil and carbamazepine decrease steroid production in zebrafish testes ( Danio rerio ). Aquatic Toxicology. 198:1-9. 2018
- The effects of chronic acetaminophen exposure on the kidney, gill and liver in rainbow trout ( Oncorhynchus mykiss ). Aquatic Toxicology. 198:20-29. 2018
- Micronuclei formation in rainbow trout cells exposed to multiple stressors: Morpholine, heat shock, and ionizing radiation. Toxicology in Vitro. 47:38-47. 2018
- The effects of fluctuating temperature regimes on the embryonic development of lake whitefish (Coregonus clupeaformis). Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 214:19-29. 2017
- Development of the embryonic heat shock response and the impact of repeated thermal stress in early stage lake whitefish ( Coregonus clupeaformis ) embryos. Journal of Thermal Biology. 69:294-301. 2017
- Initial Characterization of the Growth Stimulation and Heat-Shock-Induced Adaptive Response in Developing Lake Whitefish Embryos after Ionizing Radiation Exposure. Radiation Research. 188:475-485. 2017
- Is There a Trade-Off between Radiation-Stimulated Growth and Metabolic Efficiency?. Radiation Research. 188:486-494. 2017
- Developmental effects of the industrial cooling water additives morpholine and sodium hypochlorite on lake whitefish (Coregonus clupeaformis). Environmental Toxicology and Chemistry. 36:1955-1965. 2017
- Ionizing Radiation Exposure During Pregnancy: Effects on Postnatal Development and Life. Radiation Research. 187:647-658. 2017
- A method to transform a variable thermal regime to a physiologically equivalent effective temperature. Journal of Thermal Biology. 65:21-25. 2017
- Isotopic Structure of Lake Whitefish in Lake Huron: Evidence for Regional and Local Populations Based on Resource Use. North American Journal of Fisheries Management. 37:133-148. 2017
- In Vitro Biotransformation of Two Human CYP3A Probe Substrates and Their Inhibition during Early Zebrafish Development. International Journal of Molecular Sciences. 18:217-217. 2017
- Lipid content and fatty acid profile during lake whitefish embryonic development at different incubation temperatures. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 203:201-209. 2017
- Correction to: Hanwell, et al. Zebrafish 2016 Jul;13/S1;S-153–S-163. Zebrafish. 13:596-596. 2016
- Incubation of lake whitefish (Coregonus clupeaformis) embryos in cooling water discharge and the impacts of fluctuating thermal regimes on development. Canadian Journal of Fisheries and Aquatic Sciences. 73:1213-1221. 2016
- Consistent differential resource use by sympatric lake (Coregonus clupeaformis) and round (Prosopium cylindraceum) whitefish in Lake Huron: a multi-time scale isotopic niche analysis. Canadian Journal of Fisheries and Aquatic Sciences. 73:1072-1080. 2016
- Restrictions on the Importation of Zebrafish into Canada Associated with Spring Viremia of Carp Virus. Zebrafish. 13:S153-S163. 2016
- The effects of increased constant incubation temperature and cumulative acute heat shock exposures on morphology and survival of Lake Whitefish (Coregonus clupeaformis) embryos. Journal of Thermal Biology. 57:11-20. 2016
- Thermal stress and the heat shock response in embryonic and young of the year juvenile lake whitefish. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 193:1-10. 2016
- Fine-Scale Ecological and Genetic Population Structure of Two Whitefish (Coregoninae) Species in the Vicinity of Industrial Thermal Emissions. PLoS ONE. 11:e0146656-e0146656. 2016
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Impacts of degraded
DNA on restriction enzyme associatedDNA sequencing (RADS eq). Molecular Ecology Resources. 15:1304-1315. 2015 - Assessment of biomarkers for contaminants of emerging concern on aquatic organisms downstream of a municipal wastewater discharge. Science of the Total Environment. 530-531:140-153. 2015
- Embryonic development of lake whitefish Coregonus clupeaformis: a staging series, analysis of growth and effects of fixation. Journal of Fish Biology. 87:539-558. 2015
- Embryonic critical windows: changes in incubation temperature alter survival, hatchling phenotype, and cost of development in lake whitefish (Coregonus clupeaformis). Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology. 185:315-331. 2015
- Critical windows in embryonic development: Shifting incubation temperatures alter heart rate and oxygen consumption of Lake Whitefish (Coregonus clupeaformis) embryos and hatchlings. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 179:71-80. 2015
- Expression patterns of cytochrome P450 3B and 3C genes in model fish species. Comparative Biochemistry and Physiology, Part C. 166:115-125. 2014
- A Self‐Contained, Controlled Hatchery System for Rearing Lake Whitefish Embryos for Experimental Aquaculture. Progressive Fish-Culturist. 76:179-184. 2014
- Effects of chronic, parental pharmaceutical exposure on zebrafish (Danio rerio) offspring. Aquatic Toxicology. 151:124-134. 2014
- The Cytochrome P450 Superfamily Complement (CYPome) in the Annelid Capitella teleta. PLoS ONE. 9:e107728-e107728. 2014
- Chronic effects of exposure to a pharmaceutical mixture and municipal wastewater in zebrafish. Aquatic Toxicology. 132-133:212-222. 2013
- Chronic, low concentration exposure to pharmaceuticals impacts multiple organ systems in zebrafish. Aquatic Toxicology. 132-133:200-211. 2013
- In vitro inhibition of cytochrome P450-mediated reactions by gemfibrozil, erythromycin, ciprofloxacin and fluoxetine in fish liver microsomes. Aquatic Toxicology. 109:259-266. 2012
- Functional Screening of Cytochrome P450 Activity and Uncoupling by Capillary Electrophoresis. Analytical Chemistry. 84:862-866. 2012
- Phylogenetic and functional analyses of the cytochrome P450 family 4. Molecular Phylogenetics and Evolution. 62:458-471. 2012
- Phylogenetic and Functional Analysis of the Vertebrate Cytochrome P450 2 Family. Journal of Molecular Evolution. 72:56-71. 2011
- Characterization of vitellogenin gene expression in round goby (Neogobius melanostomus) using a quantitative polymerase chain reaction assay. Environmental Toxicology and Chemistry. 29:2751-2760. 2010
- Functional differences in the cytochrome P450 1 family enzymes from Zebrafish (Danio rerio) using heterologously expressed proteins. Molecular Cell Biology Research Communications. 502:17-22. 2010
- Signatures of contamination in invasive round gobies (Neogobius melanostomus): A double strike for ecosystem health?. Ecotoxicology and Environmental Safety. 73:1755-1764. 2010
- Cytochrome P450-mediated 17β-estradiol metabolism in zebrafish (Danio rerio). Journal of Endocrinology. 206:317-325. 2010
- Assessment of cytochrome P450 fluorometric substrates with rainbow trout and killifish exposed to dexamethasone, pregnenolone-16α-carbonitrile, rifampicin, and β-naphthoflavone. Aquatic Toxicology. 97:324-333. 2010
- Cross-species comparison of fluoxetine metabolism with fish liver microsomes. Chemosphere. 79:26-32. 2010
- Catalytic and immunochemical detection of hepatic and extrahepatic microsomal cytochrome P450 1A1 (CYP1A1) in white-sided dolphin (Lagenorhynchus acutus). Aquatic Toxicology. 96:216-224. 2010
- Microinjection in a microfluidic format using flexible and compliant channels and electroosmotic dosage control. Lab on a Chip. 9:3202-3202. 2009
- Changes in persistent contaminant concentration and CYP1A1 protein expression in biopsy samples from northern bottlenose whales, Hyperoodon ampullatus, following the onset of nearby oil and gas development. Environmental Pollution. 152:205-216. 2008
- Correlates of Cytochrome P450 1A1 Expression in Bottlenose Dolphin (Tursiops truncatus) Integument Biopsies. Toxicological Sciences. 97:111-119. 2007
- A randomised comparison of melphalan with prednisone or dexamethasone as induction therapy and dexamethasone or observation as maintenance therapy in multiple myeloma: NCIC CTG MY.7. British Journal of Haematology. 136:203-211. 2007
- Cytochrome P4501A is induced in endothelial cell lines from the kidney and lung of the bottlenose dolphin, Tursiops truncatus. Aquatic Toxicology. 76:295-305. 2006
- Systemic Effects of Arctic Pollutants in Beluga Whales Indicated by CYP1A1 Expression. Environmental Health Perspectives. 113:1594-1599. 2005
- Characterization of a cetacean aromatase (CYP19) and the phylogeny and functional conservation of vertebrate aromatase. General and Comparative Endocrinology. 140:74-83. 2005
- Induction of Cetacean Cytochrome P4501A1 by -Naphthoflavone Exposure of Skin Biopsy Slices. Toxicological Sciences. 80:268-275. 2004
- CYTOCHROME P450 1A1 EXPRESSION IN CETACEAN INTEGUMENT: IMPLICATIONS FOR DETECTING CONTAMINANT EXPOSURE AND EFFECTS. Marine Mammal Science. 20:554-566. 2004
- Regiocontrol in the Oxidative Radical Fragmentation of Benzilidene Acetals and Its Mechanistic Implications. Journal of Organic Chemistry. 69:563-565. 2004
- Experimental exposure of juvenile chinook (Oncorhynchus tshawytscha) to bleached kraft mill effluent: hepatic CYP1A induction is correlated with DNA adducts but not with organochlorine residues. Aquatic Toxicology. 53:49-63. 2001
- CYP1A localization in Beluga whales (Delphinapterus leucas) from the St. Lawrence Estuary and the Arctic. Marine Environmental Research. 50:67-67. 2000
- Measuring the potency of pulp mill effluents for induction of hepatic mixed-function oxygenase activity in fish.. Journal of Toxicology and Environmental Health - Part A. 49:83-110. 1996
- AN INPUT-OUTPUT-ANALYSIS OF MAINES FISHERIES. Marine Fisheries Review. 44:1-7. 1982
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preprints
- Metformin and guanylurea reduce survival, but have limited sublethal effects in larval zebrafish (Danio rerio) 2023
- Effect of elevated embryonic incubation temperature on the temperature preference of juvenile lake (Coregonus clupeaformis) and round whitefish (Prosopium cylindraceum) 2023
- Evaluating tank acclimation and trial length for shuttle box temperature preference assays 2020
- Evolved for success in novel environments: The round goby genome 2019
- Elevated temperature during rearing diminishes swimming and disturbs the metabolism of yellow perch larvae
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theses