Journal article
Chronic, low concentration exposure to pharmaceuticals impacts multiple organ systems in zebrafish
Abstract
Pharmaceuticals are found in both receiving and drinking water due to their persistent release in waste-water effluents, raising concerns for environmental and human health. Chronic, aqueous exposure of zebrafish (Danio rerio) to environmentally relevant concentrations of acetaminophen (ACE), venlafaxaine (VEN) (10μgL(-1)), carbamazepine (CBZ) and gemfibrozil (GEM) (0.5 and 10μgL(-1)) decreased reproductive output. Atretic oocytes and altered …
Authors
Galus M; Kirischian N; Higgins S; Purdy J; Chow J; Rangaranjan S; Li H; Metcalfe C; Wilson JY
Journal
Aquatic Toxicology, Vol. 132, , pp. 200–211
Publisher
Elsevier
Publication Date
May 2013
DOI
10.1016/j.aquatox.2012.12.021
ISSN
0166-445X