Journal article
Gemfibrozil and carbamazepine decrease steroid production in zebrafish testes (Danio rerio)
Abstract
Gemfibrozil (GEM) and carbamazepine (CBZ) are two environmentally relevant pharmaceuticals and chronic exposure of fish to these compounds has decreased androgen levels and fish reproduction in laboratory studies. The main focus of this study was to examine the effects of GEM and CBZ on testicular steroid production, using zebrafish as a model species. Chronic water borne exposures of adult zebrafish to 10 μg/L of GEM and CBZ were conducted and …
Authors
Fraz S; Lee AH; Wilson JY
Journal
Aquatic Toxicology, Vol. 198, , pp. 1–9
Publisher
Elsevier
Publication Date
May 2018
DOI
10.1016/j.aquatox.2018.02.006
ISSN
0166-445X