Journal article
Characterization of a cetacean aromatase (CYP19) and the phylogeny and functional conservation of vertebrate aromatase
Abstract
Aromatase (cytochrome P450 19, CYP19, P450arom) is the enzyme responsible for the production of estrogens, hormones critical for development and reproduction. Aromatase was sequenced from a white-sided dolphin (Lagenorhynchus acutus) ovary, transiently transfected into HEK 293 cells, and the expressed protein was characterized for aromatase activity in the presence of androstenedione and testosterone and after exposure to the aromatase …
Authors
Wilson JY; McArthur AG; Stegeman JJ
Journal
General and Comparative Endocrinology, Vol. 140, No. 1, pp. 74–83
Publisher
Elsevier
Publication Date
January 2005
DOI
10.1016/j.ygcen.2004.10.004
ISSN
0016-6480