Journal article
Expression patterns of cytochrome P450 3B and 3C genes in model fish species
Abstract
Cytochrome P450 (CYP) 3 enzymes are highly expressed in detoxification organs and play an important role in xenobiotic metabolism. In fish, the CYP3 family is diversified and includes several subfamilies (CYP3B, CYP3C, and CYP3D) not found in mammals. The functional role and expression patterns of these novel genes are unknown. In this study, the expression patterns of novel teleost CYP3 genes were determined in medaka(Oryzias latipes; CYP3B4, …
Authors
Shaya L; Dejong C; Wilson JY
Journal
Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology, Vol. 166, , pp. 115–125
Publisher
Elsevier
Publication Date
November 2014
DOI
10.1016/j.cbpc.2014.06.008
ISSN
1532-0456
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AnimalsAquacultureAryl Hydrocarbon HydroxylasesCytochrome P-450 Enzyme SystemFemaleFish ProteinsFishesGene Expression Regulation, DevelopmentalGene Expression Regulation, EnzymologicIntestinal MucosaIsoenzymesLiverMaleModels, BiologicalOrgan SpecificityOryziasResponse ElementsSex CharacteristicsSpecies SpecificityZebrafishZebrafish Proteins