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The effects of parental carbamazepine and...
Journal article

The effects of parental carbamazepine and gemfibrozil exposure on sexual differentiation in zebrafish (Danio rerio)

Abstract

The effects of parental exposure to pharmaceuticals on sexual differentiation in F1 offspring were examined in zebrafish (Danio rerio). Adult zebrafish were exposed to 0 or 10 μg/L of carbamazepine or gemfibrozil for 6 wk and bred in pairwise crosses to generate 7 distinct lineages. Lineages were formed with both parents from the same treatment group or with only one parent exposed, to delineate between maternal and paternal effects. The F1 …

Authors

Hammill KM; Fraz S; Lee AH; Wilson JY

Journal

Environmental Toxicology and Chemistry, Vol. 37, No. 6, pp. 1696–1706

Publisher

Oxford University Press (OUP)

Publication Date

February 24, 2018

DOI

10.1002/etc.4120

ISSN

0730-7268