Quantitative Trait Loci Concept

Vocabulary Service

MeSH

Overview

subject area of

A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression Journal Articles
A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease Journal Articles
A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease Journal Articles
A long noncoding RNA from the HBS1L-MYB intergenic region on chr6q23 regulates human fetal hemoglobin expression Journal Articles
A principal component regression based genome wide analysis approach reveals the presence of a novel QTL on BTA7 for MAP resistance in holstein cattle Journal Articles
Analytical strategies to include the X‐chromosome in variance heterogeneity analyses: Evidence for trait‐specific polygenic variance structure Journal Articles
Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3 Journal Articles
BCL11A is a major HbF quantitative trait locus in three different populations with β-hemoglobinopathies Journal Articles
CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer Journal Articles
Causes and Consequences of Genetic Background Effects Illuminated by Integrative Genomic Analysis Journal Articles
Contribution of Large Region Joint Associations to Complex Traits Genetics Journal Articles
Correction of chromosomal mutation and random integration in embryonic stem cells with helper-dependent adenoviral vectors Journal Articles
Dynamic interaction between fetal adversity and a genetic score reflecting dopamine function on developmental outcomes at 36 months Journal Articles
Fetal globin gene inducers: novel agents and new potential Journal Articles
Fetal hemoglobin in sickle cell anemia: Molecular characterization of the unusually high fetal hemoglobin phenotype in African Americans Journal Articles
Fetal hemoglobin in sickle cell anemia: Saudi patients from the Southwestern province have similar HBB haplotypes but higher HbF levels than African Americans Journal Articles
Gene-centric Meta-analysis in 87,736 Individuals of European Ancestry Identifies Multiple Blood-Pressure-Related Loci Journal Articles
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits Journal Articles
Genome-Wide Association Meta-analysis of Neuropathologic Features of Alzheimer's Disease and Related Dementias Journal Articles
Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2 Journal Articles
Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer Journal Articles
Genome-wide germline correlates of the epigenetic landscape of prostate cancer Journal Articles
Genome-wide linkage analysis of systolic blood pressure slope using the Genetic Analysis Workshop 13 data sets Journal Articles
Genome‐wide study identifies novel genes associated with bone toxicities in children with acute lymphoblastic leukaemia Journal Articles
Identification of Genetic Loci Underlying the Phenotypic Constructs of Autism Spectrum Disorders Journal Articles
Identification of QTLs Associated with Virulence Related Traits and Drug Resistance in Cryptococcus neoformans Journal Articles
Integrative Genetic Variation, DNA Methylation, and Gene Expression Analysis of Escitalopram and Aripiprazole Treatment Outcomes in Depression: A CAN-BIND-1 Study Journal Articles
K45R variant of squalene synthase increases total cholesterol levels in two study samples from a French Canadian population Journal Articles
Large meta-analysis of genome-wide association studies identifies five loci for lean body mass Journal Articles
Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci Journal Articles
Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation Journal Articles
Meta-analysis of SNPs involved in variance heterogeneity using Levene’s test for equal variances Journal Articles
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction Journal Articles
Multi-ethnic genome-wide association study for atrial fibrillation Journal Articles
Multilocus sequence analyses reveal extensive diversity and multiple origins of fluconazole resistance in Candida tropicalis from tropical China Journal Articles
New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders Journal Articles
On the Use of Variance per Genotype as a Tool to Identify Quantitative Trait Interaction Effects: A Report from the Women's Genome Health Study Journal Articles
Penetrance of Polygenic Obesity Susceptibility Loci across the Body Mass Index Distribution Journal Articles
Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions Journal Articles
Risk Alleles in/near ADCY5, ADRA2A, CDKAL1, CDKN2A/B, GRB10, and TCF7L2 Elevate Plasma Glucose Levels at Birth and in Early Childhood: Results from the FAMILY Study Journal Articles
SNPs in the bovine IL-10 receptor are associated with somatic cell score in Canadian dairy bulls Journal Articles
Susceptibility to chronic pain following nerve injury is genetically affected by CACNG2 Journal Articles
The LASSO and Sparse Least Squares Regression Methods for SNP Selection in Predicting Quantitative Traits Journal Articles
The association of HBG2, BCL11A, and HMIP polymorphisms with fetal hemoglobin and clinical phenotype in Iraqi Kurds with sickle cell disease Journal Articles
The genetic basis of asymptomatic codon 8 frame‐shift (HBB:c25_26delAA) β⁰‐thalassaemia homozygotes Journal Articles
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies Journal Articles
eQTL Set–Based Association Analysis Identifies Novel Susceptibility Loci for Barrett Esophagus and Esophageal Adenocarcinoma Journal Articles
α⁺-Thalassemia Trait Caused by a Frameshift Mutation in Exon 2 of the α2-Globin Gene [HBA2 c.244delT] Journal Articles