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Multi-ethnic genome-wide association study for...
Journal article

Multi-ethnic genome-wide association study for atrial fibrillation

Abstract

Atrial fibrillation (AF) affects more than 33 million individuals worldwide1 and has a complex heritability2. We conducted the largest meta-analysis of genome-wide association studies (GWAS) for AF to date, consisting of more than half a million individuals, including 65,446 with AF. In total, we identified 97 loci significantly associated with AF, including 67 that were novel in a combined-ancestry analysis, and 3 that were novel in a …

Authors

Roselli C; Chaffin MD; Weng L-C; Aeschbacher S; Ahlberg G; Albert CM; Almgren P; Alonso A; Anderson CD; Aragam KG

Journal

Nature Genetics, Vol. 50, No. 9, pp. 1225–1233

Publisher

Springer Nature

Publication Date

9 2018

DOI

10.1038/s41588-018-0133-9

ISSN

1061-4036