Endoplasmic Reticulum Chaperone BiP Concept

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• Activated protein C modulates inflammation, apoptosis and tissue factor procoagulant activity by regulating endoplasmic reticulum calcium depletion in blood monocytes  Academic Article
• Activation of the Unfolded Protein Response Occurs at All Stages of Atherosclerotic Lesion Development in Apolipoprotein E–Deficient Mice  Academic Article
• Activin A and Cell-Surface GRP78 Are Novel Targetable RhoA Activators for Diabetic Kidney Disease  Academic Article
• Anti-GRP78 autoantibodies induce endothelial cell activation and accelerate the development of atherosclerotic lesions  Academic Article
• Association of Multiple Cellular Stress Pathways With Accelerated Atherosclerosis in Hyperhomocysteinemic Apolipoprotein E-Deficient Mice  Academic Article
• Asymmetric modulation of a catecholamine-regulated protein in the rat brain, following quinpirole administration  Academic Article
• Autoantibodies against the cell surface–associated chaperone GRP78 stimulate tumor growth via tissue factor  Academic Article
• Cell surface expression of 78-kDa glucose-regulated protein (GRP78) mediates diabetic nephropathy  Academic Article
• Characterization of Retinal Microvascular Complications and the Effects of Endoplasmic Reticulum Stress in Mouse Models of Diabetic Atherosclerosis  Academic Article
• Characterization of the stress-inducing effects of homocysteine  Academic Article
• Chemical and biosynthetic evolution of the antimycin-type depsipeptides  Academic Article
• ER stress contributes to renal proximal tubule injury by increasing SREBP-2-mediated lipid accumulation and apoptotic cell death  Academic Article
• Endoplasmic Reticulum Chaperone GRP78 Protects Heart From Ischemia/Reperfusion Injury Through Akt Activation  Academic Article
• Endoplasmic Reticulum Chaperone Protein GRP78 Protects Cells from Apoptosis Induced by Topoisomerase Inhibitors  Academic Article
• Evidence of Endoplasmic Reticulum Stress Mediating Cell Death in Transplanted Human Islets  Academic Article
• GRP78 (Glucose-Regulated Protein of 78 kDa) Promotes Cardiomyocyte Growth Through Activation of GATA4 (GATA-Binding Protein 4)  Academic Article
• GRP78 and CHOP modulate macrophage apoptosis and the development of bleomycin-induced pulmonary fibrosis  Academic Article
• Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue  Academic Article
• Getting a GRP on Tissue Factor Activation  Academic Article
• Glucosamine-Induced Endoplasmic Reticulum Stress Promotes ApoB100 Degradation  Academic Article
• Glucose‐regulated protein ( GRP78 ) is an important cell surface receptor for viral invasion, cancers, and neurological disorders  Academic Article
• Hexosamine biosynthesis pathway flux promotes endoplasmic reticulum stress, lipid accumulation, and inflammatory gene expression in hepatic cells  Academic Article
• Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways  Academic Article
• Hsp90 inhibitors, GA and 17AAG, lead to ER stress-induced apoptosis in rat histiocytoma  Academic Article
• Impaired endoplasmic reticulum stress response in bipolar disorder: cellular evidence of illness progression  Academic Article
• Induction of GRP78 by valproic acid is dependent upon histone deacetylase inhibition  Academic Article
• Induction of the unfolded protein response after monocyte to macrophage differentiation augments cell survival in early atherosclerotic lesions  Academic Article
• Interrelationship Between Cardiac Hypertrophy, Heart Failure, and Chronic Kidney Disease  Academic Article
• Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained  Academic Article
• Metabolic Syndrome and Acute Hyperglycemia Are Associated With Endoplasmic Reticulum Stress in Human Mononuclear Cells  Academic Article
• Novel mechanism of action for the mood stabilizer lithium  Academic Article
• Overexpression of the 78-kDa Glucose-regulated Protein/Immunoglobulin-binding Protein (GRP78/BiP) Inhibits Tissue Factor Procoagulant Activity  Academic Article
• Peroxynitrite Causes Endoplasmic Reticulum Stress and Apoptosis in Human Vascular Endothelium  Academic Article
• Pharmacologic inhibition of S1P attenuates ATF6 expression, causes ER stress and contributes to apoptotic cell death  Academic Article
• Role of Endoplasmic Reticulum Calcium Disequilibria in the Mechanism of Homocysteine-Induced ER Stress  Academic Article
• TDAG51 mediates epithelial-to-mesenchymal transition in human proximal tubular epithelium  Academic Article
• The Unfolded Protein Response in Health and Disease  Academic Article
• The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response  Academic Article
• The loss-of-function PCSK9Q152H variant increases ER chaperones GRP78 and GRP94 and protects against liver injury  Academic Article
• The unfolded protein response is triggered following a single, unaccustomed resistance-exercise bout  Academic Article
• Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3  Academic Article