Cytochrome P-450 Enzyme System Concept

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• 1,4-Dihydropyridine Scaffold in Medicinal Chemistry, The Story So Far And Perspectives (Part 2): Action in Other Targets and Antitargets  Journal Articles
• CYP2E1,GSTM1andGSTT1genetic polymorphisms and susceptibility to antituberculosis drug-induced hepatotoxicity: a nested case-control study  Journal Articles
• A Stereoselective Hydroxylation Step of Alkaloid Biosynthesis by a Unique Cytochrome P450 in Catharanthus roseus  Journal Articles
• A mechanism for the loss of cytochrome P-450 in primary mouse hepatocytes  Journal Articles
• A novel electrophoretic pattern of induction of rat liver microsomal membrane polypeptides by 2-acetylaminofluorene, nitrosamine and azo dye administration  Journal Articles
• A relative deficiency of cytochrome P-450 and aryl hydrocarbon [benzo(a)pyrene] hydroxylase in hyperplastic nodules induced by 2-acetylaminofluorene in rat liver.  Journal Articles
• Acetylation phenotype and cytochrome P450IA2 phenotype are unlikely to be associated with peripheral arterial disease  Journal Articles
• American Society of Hematology 2018 guidelines for management of venous thromboembolism: optimal management of anticoagulation therapy  Journal Articles
• Are they being used safely? A retrospective cross-sectional tertiary health care survey of selective serotonin reuptake inhibitors prescribing practice in Singapore  Journal Articles
• Assessment of cytochrome P450 fluorometric substrates with rainbow trout and killifish exposed to dexamethasone, pregnenolone-16α-carbonitrile, rifampicin, and β-naphthoflavone  Journal Articles
• Association between induction of aryl hydrocarbon hydroxylase and depression of uroporphyrinogen decarboxylase activity.  Journal Articles
• Binding of anticonvulsant drugs to cytochrome P-450: correlation with evidence of induction of hepatic microsomal enzymes  Journal Articles
• CYP3C gene regulation by the aryl hydrocarbon and estrogen receptors in zebrafish  Journal Articles
• Calcitriol regulates the expression of the genes encoding the three key vitamin D₃ hydroxylases and the drug‐metabolizing enzyme CYP3A4 in the human fetal intestine  Journal Articles
• Carbon monoxide‐induced relaxation of the ductus arteriosus in the lamb: evidence against the prime role of guanylyl cyclase  Journal Articles
• Classification, hepatotoxic mechanisms, and targets of the risk ingredients in traditional Chinese medicine-induced liver injury  Journal Articles
• Clonal Expansion and Emergence of Environmental Multiple-Triazole-Resistant Aspergillus fumigatus Strains Carrying the TR34/L98H Mutations in the cyp51A Gene in India  Journal Articles
• Clopidogrel in acute coronary syndromes: Where are we now?  Journal Articles
• Comparative in vivo expression of the calcitriol-24-hydroxylase gene in kidney and intestine  Journal Articles
• Considerations when prescribing trimethoprim-sulfamethoxazole  Journal Articles
• Correlation between Azole Susceptibilities, Genotypes, and ERG11 Mutations in Candida albicans Isolates Associated with Vulvovaginal Candidiasis in China  Journal Articles
• Cross-species comparison of fluoxetine metabolism with fish liver microsomes  Journal Articles
• Cytochrome P450-mediated 17β-estradiol metabolism in zebrafish (Danio rerio)  Journal Articles
• Diversity and origins of Indian multi‐triazole resistant strains of Aspergillus fumigatus  Journal Articles
• Effect of whole-body hyperthermia on hepatic cytochrome P450  Journal Articles
• Effects in Rats of Maternal Exposure to Raspberry Leaf and Its Constituents on the Activity of Cytochrome P450 Enzymes in the Offspring  Journal Articles
• Effects of iron binding agents on Saccharomyces cerevisiae growth and cytochrome P450 content  Journal Articles
• Effects of phenobarbital and 3-methylcholanthrene pretreatment on size, sedimentation velocity, and mixed function oxygenase activity of rat hepatocytes.  Journal Articles
• Evidence against a regulatory role for heme oxygenase in hepatic heme synthesis  Journal Articles
• Experimental porphyria  Journal Articles
• Expression of Prostaglandin I₂Synthase, but Not Prostaglandin E Synthase, Changes in Myometrium of Women at Term Pregnancy  Journal Articles
• Expression of the 1,25-dihydroxyvitamin D3-24-hydroxylase gene in rat intestine: Response to calcium, vitamin D3 and calcitriol administration in vivo  Journal Articles
• Expression patterns of cytochrome P450 3B and 3C genes in model fish species  Journal Articles
• Fetal Serotonin Reuptake Inhibitor Antidepressant Exposure: Maternal and Fetal Factors  Journal Articles
• Functional Screening of Cytochrome P450 Activity and Uncoupling by Capillary Electrophoresis  Journal Articles
• Functional differences in the cytochrome P450 1 family enzymes from Zebrafish (Danio rerio) using heterologously expressed proteins  Journal Articles
• Genes controlling malathion resistance in a laboratory-selected population of Drosophila melanogaster  Journal Articles
• Grapefruit.  Journal Articles
• Hepatic biomarkers of sediment-associated pollution in juvenile turbot, Scophthalmus maximus L.  Journal Articles
• Heterogeneity among lists of cautioned or prohibited drugs in protocols of early-phase oncology trials  Journal Articles
• Homogeneous interferon from E. coli depresses hepatic cytochrome P-450 and drug biotransformation  Journal Articles
• Identification and developmental expression of the full complement of Cytochrome P450 genes in Zebrafish  Journal Articles
• In vitro evaluation of human cytochrome P450 and P-glycoprotein-mediated metabolism of some phytochemicals in extracts and formulations of African potato  Journal Articles
• In vitro inhibition of cytochrome P450-mediated reactions by gemfibrozil, erythromycin, ciprofloxacin and fluoxetine in fish liver microsomes  Journal Articles
• Induction and substrate specificity of the lanosterol 14 alpha-demethylase from Saccharomyces cerevisiae Y222  Journal Articles
• Inhibition of the contraction of the ductus arteriosus to oxygen by 1‐aminobenzotriazole, a mechanism‐based inactivator of cytochrome P450  Journal Articles
• Inhibition of the synthesis of hepatic cytochrome P-450 by the interferon-inducing agent poly rI.rC  Journal Articles
• Interactions between detoxification mechanisms and excretion in Malpighian tubules ofDrosophila melanogaster  Journal Articles
• Interferon-mediated depression of cytochrome P-450-dependent drug biotransformation.  Journal Articles
• Key factors of susceptibility to anti-tuberculosis drug-induced hepatotoxicity  Journal Articles
• Metabolite profiling reveals a role for intercellular dihydrocamalexic acid in the response of mature Arabidopsis thaliana to Pseudomonas syringae  Journal Articles
• Non-sterol structural probes of the lanosterol 14α-demethylase from Saccharomyces cerevisiae  Journal Articles
• Phylogenetic Analysis of the Cytochrome P450 3 (CYP3) Gene Family  Journal Articles
• Phylogenetic and Functional Analysis of the Vertebrate Cytochrome P450 2 Family  Journal Articles
• Phylogenetic and functional analyses of the cytochrome P450 family 4  Journal Articles
• Proton Pump Inhibitors and Clopidogrel – Hazardous Drug Interaction or Hazardous Interpretation of Data?  Journal Articles
• Reactive Oxygen Species, Diabetes and Toxicity in the Placenta – A Workshop Report  Journal Articles
• Relationship between the antiviral effects of interferons and their abilities to depress cytochrome P-450  Journal Articles
• Release of ferrous iron from ferritin by liver microsomes: a possible role in the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin  Journal Articles
• Retinoid requirements in the reproduction of zebrafish  Journal Articles
• Sediment TCDD-EQs and EROD and MROD Activities in Ranid Frogs from Agricultural and Nonagricultural Sites in Michigan (USA)  Journal Articles
• Spectroscopic evidence of interaction between 2-allyl-2-isopropylacetamide and cytochrome P-450 of rat liver microsomes  Journal Articles
• Studies using sedimentation velocity on heterogeneity of size and function of hepatocytes from mature male rats.  Journal Articles
• Systematic Overview of Drug Interactions with Antidepressant Medications  Journal Articles
• The Cytochrome P450 Superfamily Complement (CYPome) in the Annelid Capitella teleta  Journal Articles
• The Effects of Commercial Preparations of Herbal Supplements Commonly Used by Women on the Biotransformation of Fluorogenic Substrates by Human Cytochromes P450  Journal Articles
• The Pattern of Glucocorticoid and Estrogen Receptors May Explain Differences in Steroid Dependency of Intrauterine Prostaglandin Production at Parturition in Sheep  Journal Articles
• The cytochrome P450 (CYP) superfamily in cnidarians  Journal Articles
• The metabolism of leukotrienes, detoxification of reactive oxygen species and the activity of the cytochrome P450 mixed function oxidase system in sensitised guinea-pig lungs  Journal Articles
• [Minimizing the risks associated with QTc prolongation in people with schizophrenia. A consensus statement by the Cardiac Safety in Schizophrenia Group].  Journal Articles