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Retinoid requirements in the reproduction of...
Journal article

Retinoid requirements in the reproduction of zebrafish

Abstract

This study examines whether retinoids are essential in the reproduction of zebrafish. Using RT-PCR, it was shown that the ovaries and testes express enzymes that synthesize and metabolize the hormone retinoic acid (RA) (raldh2 and cyp26a, respectively), and RA receptors (raraa, rarga, rxrba, rxrbb, rxrga but not rxrab). Three new isoforms of rxrba were also observed in a variety of tissues. In other experiments, zebrafish were exposed for 11 d …

Authors

Alsop D; Matsumoto J; Brown S; Van Der Kraak G

Journal

General and Comparative Endocrinology, Vol. 156, No. 1, pp. 51–62

Publisher

Elsevier

Publication Date

March 2008

DOI

10.1016/j.ygcen.2007.11.008

ISSN

0016-6480