Journal article
The Pattern of Glucocorticoid and Estrogen Receptors May Explain Differences in Steroid Dependency of Intrauterine Prostaglandin Production at Parturition in Sheep
Abstract
BackgroundWe have recently described two distinct pathways of intrauterine prostaglandin (PG) synthesis: a cortisol-dependent/estradiol-independent mechanism within trophoblast tissue leading to elevations in fetal plasma PGE2α and an estradiol-dependent mechanism within maternal endometrium that leads to increased maternal plasma PGF22α. We hypothesized that the differential effects of Cortisol and estradiol on intrauterine PGH synthase-II …
Authors
Whittle WL; Holloway AC; Lye S; Challis JRG; Gibb W
Journal
Reproductive Sciences, Vol. 13, No. 7, pp. 506–511
Publisher
Springer Nature
Publication Date
October 2006
DOI
10.1016/j.jsgi.2006.07.003
ISSN
1933-7191