Half-Life Concept

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18 F-Labeled perfluorocarbon droplets for positron emission tomography imaging Academic Article
A Barbourin-albumin Fusion Protein that Is Slowly Cleared In Vivo Retains the Ability to Inhibit Platelet Aggregation In Vitro Academic Article
A Multicenter Study of Recombinant Factor VIII (RecombinateTM) in Previously Treated Patients with Hemophilia A Academic Article
A Phase 1 Study of Mapatumumab (Fully Human Monoclonal Antibody to TRAIL-R1) in Patients with Advanced Solid Malignancies Academic Article
A phase I study of oxidized raffinose cross-linked human hemoglobin Academic Article
A shorter plasma half life does not predict less drug accumulation. Academic Article
Antibiotics for pneumonia therapy Academic Article
Characterization of a long-acting recombinant human serum albumin-atrial natriuretic factor (ANF) expressed in Pichia pastoris Academic Article
Clinical pharmacology of propafenone. Academic Article
Comparative pharmacokinetics and safety assessment of transdermal berberine and dihydroberberine Academic Article
Comparative pharmacokinetics of two extended half‐life FVIII concentrates (Eloctate and Adynovate) in adolescents with hemophilia A: Is there a difference? Academic Article
Corticotropin-Releasing Factor: Pharmacokinetics in Man Academic Article
Decreased platelet thrombogenecity in association with increased platelet turnover and vascular damage Academic Article
Differential modes of chemical decay for early and late lambda messenger RNA Academic Article
Dipyridamole disposition after chronic administration: Effect of aspirin Academic Article
Direct comparison of two extended half-life PEGylated recombinant FVIII products: a randomized, crossover pharmacokinetic study in patients with severe hemophilia A Academic Article
Dose-finding and pharmacokinetics of therapeutic doses of tinzaparin in pediatric patients with thromboembolic events Academic Article
Drugs???some basic concepts Academic Article
Effect of chronic contractile activity on mRNA stability in skeletal muscle Academic Article
Effect on Intragastric pH of a PPI with a Prolonged Plasma Half-Life: Comparison between Tenatoprazole and Esomeprazole on the Duration of Acid Suppression in Healthy Male Volunteers Academic Article
Effects of Dronedarone Started Rapidly After Amiodarone Discontinuation Academic Article
Effects of Temperature and Relative Humidity on the Stability of Paper-Immobilized Antibodies Academic Article
Effects of Unfractionated Heparin, Dermatan Sulfate and Low Molecular Weight Heparin on Vessel Wall Permeability in Rabbits Academic Article
Effects of genetic fusion of factor IX to albumin on in vivo clearance in mice and rabbits Conference Paper
Efficacy of a high purity, chemically treated and nanofiltered factor IX concentrate for continuous infusion in haemophilia patients undergoing surgery Academic Article
Eight days of cyclosporine overdose: a case report. Academic Article
Evaluation of a novel structural model to describe the endogenous release of lead from bone Academic Article
Experimental investigation of the delivery pathway of ultrasmall superparamagnetic iron oxide to lymph nodes Academic Article
Extending the lifetime of anticoagulant oligodeoxynucleotide aptamers in blood Academic Article
Factor VIII concentrate for hemophilia: comparison of two heat-treated products. Academic Article
Factor VIIa gets even bigger Academic Article
Feasibility of Using Recombinant Factor VIIa in Continuous Infusion Academic Article
Fibrinogen Has a Rapid Turnover in the Healthy Newborn Lamb Academic Article
Frequency of administration of short half-life nonsteroidal anti-inflammatory analgesics (NSAID's): studies with ibuprofen. Academic Article
Fusion to Human Serum Albumin Extends the Circulatory Half-Life and Duration of Antithrombotic Action of the Kunitz Protease Inhibitor Domain of Protease Nexin 2 Academic Article
Geriatric Bone Lead Metabolism in a Female Nonhuman Primate Population Academic Article
Growth hormone-releasing factor analogs with hydrophobic residues at position 19. Effects on growth hormone releasing activity in vitro and in vivo, stability in blood plasma in vitro, and secondary structure Academic Article
Heparin kinetics in venous thrombosis and pulmonary embolism. Academic Article
In vivo anticoagulant properties of a novel nucleotide-based thrombin inhibitor and demonstration of regional anticoagulation in extracorporeal circuits Academic Article
Increased heparin clearance in experimental pulmonary embolism. Academic Article
Kinetics and Thermodynamics of Sucrose Hydrolysis from Real-Time Enthalpy and Heat Capacity Measurements Academic Article
Lamotrigine pharmacokinetics in patients receiving felbamate Academic Article
Lead concentrations in tibial and calcaneal bone in relation to the history of lead exposure Academic Article
Linking Endogenous Factor Xa Activity, a Biologically Relevant Pharmacodynamic Marker, to Edoxaban Plasma Concentrations and Clinical Outcomes in the ENGAGE AF-TIMI 48 Trial Academic Article
Loading dose of digoxin in renal failure. Academic Article
Long-acting recombinant fusion protein linking coagulation factor IX with albumin (rIX-FP) in children Academic Article
Low molecular weight heparins Academic Article
Metabolism and distribution of the virus-encoded serine proteinase inhibitor SERP-1 in healthy rabbits Academic Article
Metabolism of rabbit plasma-derived factor VII in relation to prothrombin in rabbits Academic Article
Milk thistle and indinavir: a randomized controlled pharmacokinetics study and meta-analysis Academic Article
Modulation of Clearance of Recombinant Serum Albumin by Either Glycosylation or Truncation Academic Article
Mutation of Any Site of N-Linked Glycosylation Accelerates the In Vivo Clearance of Recombinant Rabbit Antithrombin Academic Article
Nitric oxide and anti-cancer therapy Academic Article
Occupational Exposure Limits: An Approach and Calculation Aid for Extended Work Schedule Adjustments Academic Article
On Glucose Transport and Non-enzymic Glycation of Proteins In Vivo Academic Article
On the Use of Location and Occupancy Factors for Estimating External Exposure From Deposited Radionuclides Academic Article
Ontogeny and tissue distribution of alpha-1-antitrypsin of the mouse Academic Article
PHARMACOKINETICS AND PHARMACODYNAMICS OF ATRACURIUM WITH AND WITHOUT PREVIOUS SUXAMETHONIUM ADMINISTRATION Academic Article
Periprocedural Management and Approach to Bleeding in Patients Taking Dabigatran Academic Article
Pharmacokinetics and pharmacodynamics of intra-graft iloprost in femorodistal bypass surgery Academic Article
Pharmacokinetics and the transition to extended half-life factor concentrates: communication from the SSC of the ISTH Academic Article
Pharmacokinetics of High-Dose Abetimus Sodium in Normal Subjects With Specific Assessment of Effect on Coagulation Academic Article
Pharmacokinetics of NSAID with special reference to the elderly. Academic Article
Pharmacology of the low-molecular-weight heparins Academic Article
Position of residues in transmembrane peptides with respect to the lipid bilayer: a combined lipid Noes and water chemical exchange approach in phospholipid bicelles. Academic Article
Post-exercise cardiac troponin I release and clearance in normal Standardbred racehorses. Academic Article
Potent Antithrombin Activity and Delayed Clearance From the Circulation Characterize Recombinant Hirudin Genetically Fused to Albumin Academic Article
Problems in the interpretation of the in vivo measurement of calcium by the argon-37 method: an investigation of inert-gas elimination in humans. Academic Article
Proceedings: Platelet survival, fibrinolytic activity, antithrombin II (AT III) level and fibrinogen survival in venous thromboembolism (VTE). Academic Article
Prolonged Antithrombin Activity of Low-Molecular-Weight Heparins Academic Article
Propafenone disposition kinetics in cardiac arrhythmia Academic Article
Protein Engineering Thrombin for Optimal Specificity and Potency of Anticoagulant Activityin Vivo Academic Article
Randomised clinical trial: the safety and efficacy of long-acting octreotide in patients with portal hypertension Academic Article
Rapid Insulin-like Growth Factor-1-induced Changes in Granulosa Cell Thrombospondin-1 Expression In Vitro Academic Article
Recent developments in the clinical pharmacology of rolapitant: subanalyses in specific populations Academic Article
Regulation of thrombospondin-1 expression through AU-rich elements in the 3′UTR of the mRNA Academic Article
Relation of Blood Counts during Clozapine Treatment to Serum Concentrations of Clozapine and Nor-Clozapine Academic Article
Relationship Between Dose, Anticoagulant Effect and the Clinical Efficacy and Safety of Heparin Conference Paper
Review of enoxaparin and its clinical applications in venous and arterial thromboembolism Academic Article
Sequential evaluation of prostate edema after permanent seed prostate brachytherapy using CT-MRI fusion Academic Article
Serum Melatonin Response to Melatonin Administration in the Syrian Hamster Academic Article
Single-dose pharmacokinetics of intravenous ampicillin plus sulbactam in healthy elderly and young adult subjects Academic Article
Spironolactone Metabolism: Steady-State Serum Levels of the Sulfur-Containing Metabolites Academic Article
Studies of the Metabolism of Asialotransferrins: The Mechanism for the Hypercatabolism of Human Asialotransferrin in the Rabbit Academic Article
Survival of Washed Rabbit Platelets in Vivo Academic Article
Switching to extended half-life products in Canada - preliminary data Academic Article
TAFIa (CPU) is generatedin vivoat levels that can substantially affect fibrinolysis in chimpanzees in response to thrombin generation Academic Article
Tailoring treatment of haemophilia B: accounting for the distribution and clearance of standard and extended half-life FIX concentrates Academic Article
The Roles of Selected Arginine and Lysine Residues of TAFI (Pro-CPU) in Its Activation to TAFIa by the Thrombin-Thrombomodulin Complex Academic Article
The discovery and characterization of a novel nucleotide-based thrombin inhibitor Academic Article
The effect of aspirin on the pharmacokinetics of sulfinpyrazone in man Academic Article
The gastrointestinal tolerability and safety of oral bisphosphonates Academic Article
The influence of changing dose rate patterns from inhaled beta-gamma emitting radionuclide on lung cancer Academic Article
The pharmacokinetics of isoxicam in elderly patients with rheumatoid arthritis Academic Article
The sex-related differences in aspirin pharmacokinetics in rabbits and man and its relationship to antiplatelet effects Academic Article
Thrombotic thrombocytopenic purpura: a syndrome of intravascular platelet consumption. Academic Article
Trimethoprim-Sulfamethoxazole Pharmacokinetics during Continuous Ambulatory Peritoneal Dialysis (CAPD) Academic Article