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A Canadian paediatric brain tumour consortium (CPBTC) phase II molecularly targeted study of imatinib in recurrent and refractory paediatric central nervous system tumours Academic Article
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A New Strategy for Preparing Molecular Imaging and Therapy Agents Using Fluorine-Rich (Fluorous) Soluble Supports Academic Article
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A phase II and pharmacokinetic study of SB-715992, in patients with metastatic hepatocellular carcinoma: a study of the National Cancer Institute of Canada Clinical Trials Group (NCIC CTG IND.168) Academic Article
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A phase II study of ispinesib (SB-715992) in patients with metastatic or recurrent malignant melanoma: a National Cancer Institute of Canada Clinical Trials Group trial Academic Article
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An evaluation of roflumilast and PDE4 inhibitors with a focus on the treatment of asthma Academic Article
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Assessing the Economic Value of a New Antidepressant Academic Article
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Betrixaban (PRT054021): pharmacology, dose selection and clinical studies Academic Article
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Betrixaban compared with warfarin in patients with atrial fibrillation: results of a phase 2, randomized, dose-ranging study (Explore-Xa) Academic Article
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Cabazitaxel versus abiraterone or enzalutamide in poor prognosis metastatic castration-resistant prostate cancer: a multicentre, randomised, open-label, phase II trial Academic Article
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Capsaicin-induced airway obstruction in tracheally perfused guinea pig lungs. Academic Article
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Combination Epigenetic Therapy Has Efficacy in Patients with Refractory Advanced Non–Small Cell Lung Cancer Academic Article
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Comparison of Fatal or Irreversible Events With Extended‐Duration Betrixaban Versus Standard Dose Enoxaparin in Acutely Ill Medical Patients: An APEX Trial Substudy Academic Article
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Cost-effectiveness of enzalutamide versus apalutamide versus androgen deprivation therapy alone for the treatment of metastatic castration-sensitive prostate cancer in Canada Academic Article
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Current Incidence and Outcomes of Gastrointestinal Mesenchymal Tumors Including Gastrointestinal Stromal Tumors Academic Article
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Darexaban (YM150) versus enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: a randomised phase IIb dose confirmation study (ONYX-3) Academic Article
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Deep molecular responses achieved in patients with CML-CP who are switched to nilotinib after long-term imatinib Academic Article
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Dyspepsia Academic Article
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Effect of a leukotriene B4 receptor antagonist SC-53228 on ozone-induced airway hyperresponsiveness and inflammation in dogs. Academic Article
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Effect of extended‐duration thromboprophylaxis on venous thromboembolism and major bleeding among acutely ill hospitalized medical patients: a bivariate analysis Academic Article
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Effect of substituted benzamide drugs on rat striatal tyrosine hydroxylase Academic Article
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Electrophysiological Evidence That Neurokinin A Acts Via NK-1 Receptors in the Cat Dorsal Horn Academic Article
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Epigenetic therapy inhibits metastases by disrupting premetastatic niches Academic Article
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Esophageal gastrointestinal stromal tumor: report of 7 patients Academic Article
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Evaluation of bronchoconstriction induced by neurokinins and its inhibition by selective nonpeptide antagonists in conscious guinea pigs, using a double-chamber plethysmograph technique Academic Article
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Extended Thromboprophylaxis with Betrixaban in Acutely Ill Medical Patients Academic Article
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HDACi Delivery Reprograms Tumor-Infiltrating Myeloid Cells to Eliminate Antigen-Loss Variants Academic Article
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HDACi promotes inflammatory remodeling of the tumor microenvironment to enhance epitope spreading and antitumor immunity Academic Article
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Health-related quality of life in patients with major depression who are treated with moclobemide. Academic Article
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Identification and Characterization of AES-135, a Hydroxamic Acid-Based HDAC Inhibitor That Prolongs Survival in an Orthotopic Mouse Model of Pancreatic Cancer Academic Article
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Identification of both NK1 and NK2 receptors in guinea-pig airways Academic Article
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Imatinib Mesylate in Patients With Adenoid Cystic Cancers of the Salivary Glands Expressing c-kit: A Princess Margaret Hospital Phase II Consortium Study Academic Article
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Imatinib for Melanomas Harboring Mutationally Activated or Amplified KIT Arising on Mucosal, Acral, and Chronically Sun-Damaged Skin Academic Article
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Imatinib mesylate in children and adolescents with cancer Academic Article
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Influence of the poly (ADP-ribose) polymerase inhibitor 3-aminobenzamide on macrophage and granulocyte differentiation of HL-60 cells Academic Article
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Inhibition of thrombin by antithrombin III in the presence of certain glycosaminoglycans found in the mammalian aorta Academic Article
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Inhibitors of Bacterial Cystathionine β-Lyase: Leads for New Antimicrobial Agents and Probes of Enzyme Structure and Function Academic Article
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Involvement of NK1 and NK2 Receptors in Pulmonary Responses Elicited by Non-adrenergic, Non-cholinergic Vagal Stimulation in Guinea-pigs Academic Article
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Is There a Role for Betrixaban to Prevent Stroke in Medically Ill Patients? Academic Article
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Metabolic response by FDG-PET to imatinib correlates with exon 11 KIT mutation and predicts outcome in patients with mucosal melanoma Academic Article
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NK2 receptors mediate plasma extravasation in guinea-pig lower airways Academic Article
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NK1and NK2Receptors Mediate Tachykinin and Resiniferatoxin-induced Bronchospasm in Guinea Pigs Academic Article
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Neurokinin (NK2) receptors mediate nonadrenergic noncholinergic contractile responses to electrical stimulation and resiniferatoxin in guinea pig trachea Academic Article
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New Anticoagulants for Atrial Fibrillation Academic Article
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PSA declines and survival in patients with metastatic castration-resistant prostate cancer treated with enzalutamide Academic Article
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Phase II study of ispinesib in recurrent or metastatic squamous cell carcinoma of the head and neck Conference Paper
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Phosphodiesterase-4 inhibition in COPD Academic Article
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Potentiation of long-acting β2-agonist and glucocorticoid responses in human airway epithelial cells by modulation of intracellular cAMP Academic Article
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Profile of betrixaban and its potential in the prevention and treatment of venous thromboembolism Academic Article
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Prokinetics for functional dyspepsia Academic Article
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Proliferation of guinea pig tracheal epithelial cells in coculture with rat dorsal root ganglion neural cells Academic Article
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RUBY-1: a randomized, double-blind, placebo-controlled trial of the safety and tolerability of the novel oral factor Xa inhibitor darexaban (YM150) following acute coronary syndrome Academic Article
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Roflumilast attenuates allergen-induced inflammation in mild asthmatic subjects Academic Article
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Roflumilast for asthma: Efficacy findings in mechanism of action studies Academic Article
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Roflumilast for asthma: Efficacy findings in non-placebo-controlled comparator and dosing studies Academic Article
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Roflumilast for asthma: Weighing the evidence Academic Article
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Safety and efficacy of a CXCR2 antagonist in patients with severe asthma and sputum neutrophils: a randomized, placebo-controlled clinical trial Academic Article
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Safety and efficacy of an oral CCR3 antagonist in patients with asthma and eosinophilic bronchitis: a randomized, placebo-controlled clinical trial Academic Article
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Safety of enzalutamide in patients with metastatic castration‐resistant prostate cancer previously treated with docetaxel: Expanded access in North America Academic Article
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Single photon emission tomography assessment of cerebral dopamine D2 receptor blockade in schizophrenia Academic Article
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Substance P-induced histamine release in tracheally perfused guinea pig lungs Academic Article
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Systemic Therapy in Men With Metastatic Castration-Resistant Prostate Cancer: American Society of Clinical Oncology and Cancer Care Ontario Clinical Practice Guideline Academic Article
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TCF/LEF regulation of the topologically associated domain ADI promotes mESCs to exit the pluripotent ground state Academic Article
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Tachykinin receptor antagonists inhibit hyperpnea-induced bronchoconstriction in guinea pigs. Academic Article
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The Effects of Extracellular Calcium-Sensing Receptor Ligands on the Contractility of Pregnant Human Myometrium In Vitro Academic Article
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The HDAC class I-specific inhibitor entinostat (MS-275) effectively relieves epigenetic silencing of the LAT2 gene mediated by AML1/ETO Academic Article
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The Non-Vitamin K Antagonist Oral Anticoagulants in Heart Disease: Section V—Special Situations Academic Article
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The effects of a CXCR1/CXCR2 antagonist on neutrophil migration in mild atopic asthmatic subjects Academic Article
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The ground state of embryonic stem cell self-renewal Academic Article
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The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms Academic Article
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XXIII International Association for Comparative Research on Leukemia and Related Diseases Symposium: from Molecular Pathogenesis to Targeted Therapy in Leukemia and Solid Tumors Conference Paper