Benzamides Concept

subject area of

• A Canadian paediatric brain tumour consortium (CPBTC) phase II molecularly targeted study of imatinib in recurrent and refractory paediatric central nervous system tumours  Academic Article
• A New Strategy for Preparing Molecular Imaging and Therapy Agents Using Fluorine-Rich (Fluorous) Soluble Supports  Academic Article
• A phase II and pharmacokinetic study of SB-715992, in patients with metastatic hepatocellular carcinoma: a study of the National Cancer Institute of Canada Clinical Trials Group (NCIC CTG IND.168)  Academic Article
• A phase II study of ispinesib (SB-715992) in patients with metastatic or recurrent malignant melanoma: a National Cancer Institute of Canada Clinical Trials Group trial  Academic Article
• An evaluation of roflumilast and PDE4 inhibitors with a focus on the treatment of asthma  Academic Article
• Assessing the Economic Value of a New Antidepressant  Academic Article
• Betrixaban (PRT054021): pharmacology, dose selection and clinical studies  Academic Article
• Betrixaban compared with warfarin in patients with atrial fibrillation: results of a phase 2, randomized, dose-ranging study (Explore-Xa)  Academic Article
• Cabazitaxel versus abiraterone or enzalutamide in poor prognosis metastatic castration-resistant prostate cancer: a multicentre, randomised, open-label, phase II trial  Academic Article
• Capsaicin-induced airway obstruction in tracheally perfused guinea pig lungs.  Academic Article
• Combination Epigenetic Therapy Has Efficacy in Patients with Refractory Advanced Non–Small Cell Lung Cancer  Academic Article
• Comparison of Fatal or Irreversible Events With Extended‐Duration Betrixaban Versus Standard Dose Enoxaparin in Acutely Ill Medical Patients: An APEX Trial Substudy  Academic Article
• Cost-effectiveness of enzalutamide versus apalutamide versus androgen deprivation therapy alone for the treatment of metastatic castration-sensitive prostate cancer in Canada  Academic Article
• Current Incidence and Outcomes of Gastrointestinal Mesenchymal Tumors Including Gastrointestinal Stromal Tumors  Academic Article
• Darexaban (YM150) versus enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: a randomised phase IIb dose confirmation study (ONYX-3)  Academic Article
• Deep molecular responses achieved in patients with CML-CP who are switched to nilotinib after long-term imatinib  Academic Article
• Dyspepsia  Academic Article
• Effect of a leukotriene B4 receptor antagonist SC-53228 on ozone-induced airway hyperresponsiveness and inflammation in dogs.  Academic Article
• Effect of extended‐duration thromboprophylaxis on venous thromboembolism and major bleeding among acutely ill hospitalized medical patients: a bivariate analysis  Academic Article
• Effect of substituted benzamide drugs on rat striatal tyrosine hydroxylase  Academic Article
• Electrophysiological Evidence That Neurokinin A Acts Via NK-1 Receptors in the Cat Dorsal Horn  Academic Article
• Epigenetic therapy inhibits metastases by disrupting premetastatic niches  Academic Article
• Esophageal gastrointestinal stromal tumor: report of 7 patients  Academic Article
• Evaluation of bronchoconstriction induced by neurokinins and its inhibition by selective nonpeptide antagonists in conscious guinea pigs, using a double-chamber plethysmograph technique  Academic Article
• Extended Thromboprophylaxis with Betrixaban in Acutely Ill Medical Patients  Academic Article
• HDACi Delivery Reprograms Tumor-Infiltrating Myeloid Cells to Eliminate Antigen-Loss Variants  Academic Article
• HDACi promotes inflammatory remodeling of the tumor microenvironment to enhance epitope spreading and antitumor immunity  Academic Article
• Health-related quality of life in patients with major depression who are treated with moclobemide.  Academic Article
• Identification and Characterization of AES-135, a Hydroxamic Acid-Based HDAC Inhibitor That Prolongs Survival in an Orthotopic Mouse Model of Pancreatic Cancer  Academic Article
• Identification of both NK1 and NK2 receptors in guinea-pig airways  Academic Article
• Imatinib Mesylate in Patients With Adenoid Cystic Cancers of the Salivary Glands Expressing c-kit: A Princess Margaret Hospital Phase II Consortium Study  Academic Article
• Imatinib for Melanomas Harboring Mutationally Activated or Amplified KIT Arising on Mucosal, Acral, and Chronically Sun-Damaged Skin  Academic Article
• Imatinib mesylate in children and adolescents with cancer  Academic Article
• Influence of the poly (ADP-ribose) polymerase inhibitor 3-aminobenzamide on macrophage and granulocyte differentiation of HL-60 cells  Academic Article
• Inhibition of thrombin by antithrombin III in the presence of certain glycosaminoglycans found in the mammalian aorta  Academic Article
• Inhibitors of Bacterial Cystathionine β-Lyase:  Leads for New Antimicrobial Agents and Probes of Enzyme Structure and Function  Academic Article
• Involvement of NK1 and NK2 Receptors in Pulmonary Responses Elicited by Non-adrenergic, Non-cholinergic Vagal Stimulation in Guinea-pigs  Academic Article
• Is There a Role for Betrixaban to Prevent Stroke in Medically Ill Patients?  Academic Article
• Metabolic response by FDG-PET to imatinib correlates with exon 11 KIT mutation and predicts outcome in patients with mucosal melanoma  Academic Article
• NK2 receptors mediate plasma extravasation in guinea-pig lower airways  Academic Article
• NK₁and NK₂Receptors Mediate Tachykinin and Resiniferatoxin-induced Bronchospasm in Guinea Pigs  Academic Article
• Neurokinin (NK₂) receptors mediate nonadrenergic noncholinergic contractile responses to electrical stimulation and resiniferatoxin in guinea pig trachea  Academic Article
• New Anticoagulants for Atrial Fibrillation  Academic Article
• PSA declines and survival in patients with metastatic castration-resistant prostate cancer treated with enzalutamide  Academic Article
• Phase II study of ispinesib in recurrent or metastatic squamous cell carcinoma of the head and neck  Conference Paper
• Phosphodiesterase-4 inhibition in COPD  Academic Article
• Potentiation of long-acting β2-agonist and glucocorticoid responses in human airway epithelial cells by modulation of intracellular cAMP  Academic Article
• Profile of betrixaban and its potential in the prevention and treatment of venous thromboembolism  Academic Article
• Prokinetics for functional dyspepsia  Academic Article
• Proliferation of guinea pig tracheal epithelial cells in coculture with rat dorsal root ganglion neural cells  Academic Article
• RUBY-1: a randomized, double-blind, placebo-controlled trial of the safety and tolerability of the novel oral factor Xa inhibitor darexaban (YM150) following acute coronary syndrome  Academic Article
• Roflumilast attenuates allergen-induced inflammation in mild asthmatic subjects  Academic Article
• Roflumilast for asthma: Efficacy findings in mechanism of action studies  Academic Article
• Roflumilast for asthma: Efficacy findings in non-placebo-controlled comparator and dosing studies  Academic Article
• Roflumilast for asthma: Weighing the evidence  Academic Article
• Safety and efficacy of a CXCR2 antagonist in patients with severe asthma and sputum neutrophils: a randomized, placebo-controlled clinical trial  Academic Article
• Safety and efficacy of an oral CCR3 antagonist in patients with asthma and eosinophilic bronchitis: a randomized, placebo-controlled clinical trial  Academic Article
• Safety of enzalutamide in patients with metastatic castration‐resistant prostate cancer previously treated with docetaxel: Expanded access in North America  Academic Article
• Single photon emission tomography assessment of cerebral dopamine D2 receptor blockade in schizophrenia  Academic Article
• Substance P-induced histamine release in tracheally perfused guinea pig lungs  Academic Article
• Systemic Therapy in Men With Metastatic Castration-Resistant Prostate Cancer: American Society of Clinical Oncology and Cancer Care Ontario Clinical Practice Guideline  Academic Article
• TCF/LEF regulation of the topologically associated domain ADI promotes mESCs to exit the pluripotent ground state  Academic Article
• Tachykinin receptor antagonists inhibit hyperpnea-induced bronchoconstriction in guinea pigs.  Academic Article
• The Effects of Extracellular Calcium-Sensing Receptor Ligands on the Contractility of Pregnant Human Myometrium In Vitro  Academic Article
• The HDAC class I-specific inhibitor entinostat (MS-275) effectively relieves epigenetic silencing of the LAT2 gene mediated by AML1/ETO  Academic Article
• The Non-Vitamin K Antagonist Oral Anticoagulants in Heart Disease: Section V—Special Situations  Academic Article
• The effects of a CXCR1/CXCR2 antagonist on neutrophil migration in mild atopic asthmatic subjects  Academic Article
• The ground state of embryonic stem cell self-renewal  Academic Article
• The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms  Academic Article
• XXIII International Association for Comparative Research on Leukemia and Related Diseases Symposium: from Molecular Pathogenesis to Targeted Therapy in Leukemia and Solid Tumors  Conference Paper