Journal article
An evaluation of roflumilast and PDE4 inhibitors with a focus on the treatment of asthma
Abstract
INTRODUCTION: Asthma is a common chronic airway inflammatory disease characterized by diverse inflammatory events leading to airway hyperresponsiveness and reversible airflow obstruction. Corticosteroids have been the mainstay for asthma treatment due to their broad anti-inflammatory actions; however, other medications such as phosphodiesterase 4 inhibitors also demonstrate anti-inflammatory activity in the airways.
AREAS COVERED: This review …
Authors
Al-Sajee D; Yin X; Gauvreau GM
Journal
Expert Opinion on Pharmacotherapy, Vol. 20, No. 5, pp. 609–620
Publisher
Taylor & Francis
Publication Date
March 24, 2019
DOI
10.1080/14656566.2019.1570132
ISSN
1465-6566