Human gene therapy. Clinical development Journal

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Strategies to Enhance Viral Penetration of Solid Tumors. 22:1053-1060. 2011
Restoration of Vitamin C Synthesis in Transgenic Gulo^−/− Mice by Helper-Dependent Adenovirus-Based Expression of Gulonolactone Oxidase. 19:1349-1358. 2008
Encapsulation of Recombinant Cells with a Novel Magnetized Alginate for Magnetic Resonance Imaging. 16:971-984. 2005
Combined Immunotherapy and Antiangiogenic Therapy of Cancer with Microencapsulated Cells. 15:945-959. 2004
Vesicular Stomatitis Virus: A Potential Therapeutic Virus for the Treatment of Hematologic Malignancy. 15:821-831. 2004
Helper-Dependent Adenoviral Vectors Containing Modified Fiber for Improved Transduction of Developing and Mature Muscle Cells. 15:179-188. 2004
Transplantation of Monocytes: A Novel Strategy forIn VivoAugmentation of Collateral Vessel Growth. 15:1-12. 2004
Antiangiogenic Cancer Therapy with Microencapsulated Cells. 14:1065-1077. 2003
Delivery of Ciliary Neurotrophic Factor via Lentiviral-Mediated Transfer Protects Axotomized Retinal Ganglion Cells for an Extended Period of Time. 14:103-115. 2003
A Novel Approach to Tumor Suppression with Microencapsulated Recombinant Cells. 13:1157-1166. 2002
Superior Tissue-Specific Expression from Tyrosinase and Prostate-Specific Antigen Promoters/Enhancers in Helper-Dependent Compared with First-Generation Adenoviral Vectors. 13:211-224. 2002
Treatment of a Lysosomal Storage Disease, Mucopolysaccharidosis VII, with Microencapsulated Recombinant Cells. 11:2117-2127. 2000
An Enhanced System for Construction of Adenoviral Vectors by the Two-Plasmid Rescue Method. 11:693-699. 2000
A High-Efficiency Cre/loxP-Based System for Construction of Adenoviral Vectors. 10:2667-2672. 1999
Human Gene Marker/Therapy Clincal Protocols (Complete Updated Listings). 10:2037-2088. 1999
Use of a Liver-Specific Promoter Reduces Immune Response to the Transgene in Adenoviral Vectors. 10:1773-1781. 1999
Persistent Delivery of Factor IX in Mice: Gene Therapy for Hemophilia Using Implantable Microcapsules. 10:1281-1288. 1999
Adenoviral Vectors Expressing Lymphotactin and Interleukin 2 or Lymphotactin and Interleukin 12 Synergize to Facilitate Tumor Regression in Murine Breast Cancer Models. 10:697-709. 1999
Delivery of Recombinant Gene Products to the Central Nervous System with Nonautologous Cells in Alginate Microcapsules. 10:49-59. 1999
High Doses of a Helper-Dependent Adenoviral Vector Yield Supraphysiological Levels ofα₁-Antitrypsin with Negligible Toxicity. 9:2709-2716. 1998
Suppression of Immunological Response Against a Transgene Product Delivered from Microencapsulated Cells. 9:1275-1282. 1998
Combination Therapy with Interleukin-2 and Wild-Type p53 Expressed by Adenoviral Vectors Potentiates Tumor Regression in a Murine Model of Breast Cancer. 9:707-718. 1998
Adenovirus-Mediated Interleukin-10 Gene Transfer Inhibits Post-Transplant Fibrous Airway Obliteration in an Animal Model of Bronchiolitis Obliterans. 9:541-551. 1998
Delivery of Recombinant Gene Product to Canines with Nonautologous Microencapsulated Cells. 9:195-206. 1998
A Phase I Study of Adenovirus Mediated Gene Transfer of Interleukin 2 cDNA into Metastatic Breast Cancer or Melanoma. The Toronto Hospital, Toronto, Ontario, Canada. 8:1403-1414. 1997
Dendritic Cells Transduced with an Adenoviral Vector Encoding a Model Tumor-Associated Antigen for Tumor Vaccination. 8:1355-1363. 1997
Intramarrow Cytokine Gene Transfer by Adenoviral Vectors in Dogs. 8:545-553. 1997
Direct Intratumoral Injection of an Adenovirus Expressing Interleukin-12 Induces Regression and Long-Lasting Immunity That Is Associated with Highly Localized Expression of Interleukin-12. 7:1995-2002. 1996
Gene Therapy: Socioeconomic and Ethical Issues A Roundtable Discussion. 7:1139-1144. 1996
Construction of a Double Recombinant Adenovirus Vector Expressing a Heterodimeric Cytokine:In VitroandIn VivoProduction of Biologically Active Interleukin-12. 7:333-342. 1996
Growth Retardation—An Unexpected Outcome from Growth Hormone Gene Therapy in Normal Mice with Microencapsulated Myoblasts. 7:61-70. 1996
Development of Cell Lines Capable of Complementing E1, E4, and Protein IX Defective Adenovirus Type 5 Mutants. 6:1575-1586. 1995
Recombinant Truncated Dystrophin Minigenes: Construction, Expression, and Adenoviral Delivery. 6:1477-1485. 1995
Correction of the Growth Defect in Dwarf Mice with Nonautologous Microencapsulated Myoblasts—An Alternate Approach to Somatic Gene Therapy. 6:165-175. 1995
Delivery of a Secretable Adenosine Deaminase Through Microcapsules–A Novel Approach to Somatic Gene Therapy. 5:1445-1455. 1994
Transduction of Human Bone Marrow by Adenoviral Vector. 5:941-948. 1994
Delivery of Recombinant Gene Products with Microencapsulated Cells In Vivo. 4:433-440. 1993
Expression of Human Factor IX by Microencapsulated Recombinant Fibroblasts. 4:291-301. 1993
Encapsulation of Recombinant Cells with a Novel Magnetized Alginate for Magnetic Resonance Imaging. 0:050707082019001-050707082019001.