selected scholarly activity
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academic article
- Conditional Deletion of AP-2β in the Periocular Mesenchyme of Mice Alters Corneal Epithelial Cell Fate and Stratification. International Journal of Molecular Sciences. 22:8730-8730. 2021
- Corneal development: Role of the periocular mesenchyme and bi-directional signaling. Experimental Eye Research. 201:108231-108231. 2020
- AP-2β is required for formation of the murine trabecular meshwork and Schlemm's canal. Experimental Eye Research. 195:108042-108042. 2020
- β-Catenin/Smad3 Interaction Regulates Transforming Growth Factor-β-Induced Epithelial to Mesenchymal Transition in the Lens. International Journal of Molecular Sciences. 20:2078-2078. 2019
- Relationship between neural crest cell specification and rare ocular diseases. Journal of Neuroscience Research. 97:7-15. 2019
- Conditional Deletion of AP-2α and AP-2β in the Developing Murine Retina Leads to Altered Amacrine Cell Mosaics and Disrupted Visual Function. Investigative Ophthalmology and Visual Science. 59:2229-2229. 2018
- Matrix metalloproteinase 9 is associated with peritoneal membrane solute transport and induces angiogenesis through β-catenin signaling. Nephrology Dialysis Transplantation. 32:gfw076-gfw076. 2017
- AP-2β Is a Downstream Effector of PITX2 Required to Specify Endothelium and Establish Angiogenic Privilege During Corneal Development. Investigative Ophthalmology and Visual Science. 57:1072-1072. 2016
- Conditional deletion of AP-2β in the cranial neural crest results in anterior segment dysgenesis and early-onset glaucoma. DMM Disease Models and Mechanisms. 9:849-861. 2016
- AP-2α is required after lens vesicle formation to maintain lens integrity. Developmental Dynamics. 243:1298-1309. 2014
- Matrix Metalloproteinase-9–Null Mice Are Resistant to TGF-β–Induced Anterior Subcapsular Cataract Formation. American Journal of Pathology. 184:2001-2012. 2014
- Altered expression of transforming growth factor beta 1 and matrix metalloproteinase-9 results in elevated intraocular pressure in mice.. Molecular Vision. 19:684-695. 2013
- Nuclear translocation of myocardin-related transcription factor-A during transforming growth factor beta-induced epithelial to mesenchymal transition of lens epithelial cells.. Molecular Vision. 19:1017-1028. 2013
- Activation of the Hedgehog Signaling Pathway in the Developing Lens Stimulates EctopicFoxE3Expression and Disruption in Fiber Cell Differentiation. Investigative Ophthalmology and Visual Science. 53:3316-3316. 2012
- Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina. Developmental Dynamics. 241:814-829. 2012
- AP-2α knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesis. Human Molecular Genetics. 19:1791-1804. 2010
- Development and use of the lens epithelial explant system to study lens differentiation and cataractogenesis. Progress in Retinal and Eye Research Progress in Retinal Research. 29:135-143. 2010
- Effect of delivery of MMP inhibitors from PDMS as a model IOL material on PCO markers. Biomaterials. 31:2399-2407. 2010
- Platelet derived growth factor B and epithelial mesenchymal transition of peritoneal mesothelial cells. Matrix Biology Collagen and Related Research Matrix. 29:97-106. 2010
- Ocular Gene Transfer of Active TGF-β Induces Changes in Anterior Segment Morphology and Elevated IOP in Rats. Investigative Ophthalmology and Visual Science. 51:308-308. 2010
- Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survival. Developmental Biology. 326:403-417. 2009
- Temporal changes in MMP mRNA expression in the lens epithelium during anterior subcapsular cataract formation. Experimental Eye Research. 88:323-330. 2009
- Corneal epithelial cell adhesion and growth on EGF-modified aminated PDMS. Journal of Biomedical Materials Research - Part A. 9999A:NA-NA. 2009
- Cell autonomous roles for AP-2α in lens vesicle separation and maintenance of the lens epithelial cell phenotype. Developmental Dynamics. 237:602-617. 2008
- Matrix metalloproteinases as mediators of primary and secondary cataracts. Expert Review of Ophthalmology. 2:931-938. 2007
- Conditional Deletion of Activating Protein 2α (AP-2α) in the Developing Retina Demonstrates Non-Cell-Autonomous Roles for AP-2α in Optic Cup Development. Molecular and Cellular Biology. 27:7497-7510. 2007
- Genetic analysis indicates that transcription factors AP-2alpha and Pax6 cooperate in the normal patterning and morphogenesis of the lens.. Molecular Vision. 13:1215-1225. 2007
- Adenoviral gene transfer of bioactive TGFbeta1 to the rodent eye as a novel model for anterior subcapsular cataract.. Molecular Vision. 13:457-469. 2007
- Lens-Specific Expression of TGF-β Induces Anterior Subcapsular Cataract Formation in the Absence of Smad3. Investigative Ophthalmology and Visual Science. 47:3450-3450. 2006
- Matrix Metalloproteinase Inhibitors Suppress Transforming Growth Factor-β-Induced Subcapsular Cataract Formation. American Journal of Pathology. 168:69-79. 2006
- The keratocyte: Corneal stromal cell with variable repair phenotypes. International Journal of Biochemistry and Cell Biology International Journal of Biochemistry. 38:1625-1631. 2006
- EGF-grafted PDMS surfaces in artificial cornea applications. Biomaterials. 26:7286-7296. 2005
- Targeted Deletion ofAP-2α Leads to Disruption in Corneal Epithelial Cell Integrity and Defects in the Corneal Stroma. Investigative Ophthalmology and Visual Science. 46:3623-3623. 2005
- Differential Regulation of Components of the Ubiquitin-Proteasome Pathway during Lens Cell Differentiation. Investigative Ophthalmology and Visual Science. 45:1194-1194. 2004
- Positive influence of AP-2α transcription factor on cadherin gene expression and differentiation of the ocular surface. Differentiation. 71:206-216. 2003
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conference paper
- Retinal Ganglion Cell Numbers In Early Post-Natal AP-2 beta Neural Crest Cell Knockout Mice. Investigative Ophthalmology and Visual Science. 2018
- MMP-9 null mice display elevated IOP due to reduced aqueous humor drainage from the trabecular meshwork. Acta Ophthalmologica Scandinavica Acta Ophthalmologica. n/a-n/a. 2015
- Glaucomatous Features Observed Following Conditional Deletion of AP-2 beta in Neural Crest Cell Populations. Investigative Ophthalmology and Visual Science. 2015
- AP-2 alpha and AP-2 beta are Required for Normal Lens Development. Investigative Ophthalmology and Visual Science. 2013
- Altered expreion of TGF beta 1 and MMP-9 results in elevated intraocular preure in mice. Investigative Ophthalmology and Visual Science. 2013
- Role of Rho-ROCK signaling in TGF beta-mediated MRTF-A localization during EMT of LECs. Investigative Ophthalmology and Visual Science. 2013
- Smad3 and MRTF regulation of TGF beta-induced EMT in mouse lens explants. Investigative Ophthalmology and Visual Science. 2013
- The potential redundant roles of AP-2 alpha and AP-2 beta in the developing and postnatal neural retina. Investigative Ophthalmology and Visual Science. 2013
- Excessive Hedgehog Signaling Results in Misexpression of Cell Cycle Proteins and Abnormal Cell Cycle Behaviour During Lens Development. Investigative Ophthalmology and Visual Science. 2010
- Cre-mediated deletion of AP-2a in the developing retina reveals intrinsic role for AP-2a in retinogenesis. Investigative Ophthalmology and Visual Science. 2005
- Effects of the MMP inhibitor, GM6001, on TGF-beta-induced gene expression in a rat subcapsular cataract model. Investigative Ophthalmology and Visual Science. 2005
- Epidermal growth factor-modified polydimethylsiloxane for keratoprostheses. Investigative Ophthalmology and Visual Science. 2005
- Gene transfer of bioactive IL-1b to the anterior chamber of the rodent eye induces a retinal phenotype similar to human proliferative vitreoretinopathy. Investigative Ophthalmology and Visual Science. 2005
- Gene transfer of bioactive TGF-b1 to the anterior chamber of the rodent eye induces anterior subcapsular cataracts and alterations to the trabecular meshwork. Investigative Ophthalmology and Visual Science. 2005
- Lens specific expression of TGF-b induces anterior subcapsular cataract formation in the absence of Smad3 signaling. Investigative Ophthalmology and Visual Science. 2005
- A conditional knockout of AP-2a in the developing lens results in an isolated ocular phenotype demonstrating an intrinsic requirement for AP-2a in the lens and eye development. Investigative Ophthalmology and Visual Science. U289-U289. 2003