Ap-2 and ocular epithelial morphogenesis

Purpose. Accumulating evidence from our laboratory suggests that AP-2 transcription factor plays an important role in the maintenance and repair of the corneal epithelium. In the current study we further pursue the function of AP-2 proteins in ocular epithelial regeneration and embryogenesis. Methods. AP-2 protein was immunolocalized to the developing ocular epithelium in mouse. A detailed morphological examination of the ocular defects of AP-2 …