Protein-Tyrosine Kinases
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1,25-Dihydroxyvitamin D3Primes Acute Promyelocytic Cells for TPA-Induced Monocytic Differentiation through Both PKC and Tyrosine Phosphorylation Cascades Academic Article
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A pharmacodynamic study of the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in metastatic colorectal cancer patients. Academic Article
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Achondroplasia–hypochondroplasia complex in a newborn infant Academic Article
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Adenosine downregulates DPPIV on HT-29 colon cancer cells by stimulating protein tyrosine phosphatase(s) and reducing ERK1/2 activity via a novel pathway Academic Article
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Assembly of Bcl-2 into microsomal and outer mitochondrial membranes Academic Article
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Brain-derived neurotrophic factor and TrkB expression in the “oldest-old,” the 90+ Study: correlation with cognitive status and levels of soluble amyloid-beta Academic Article
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CANTRK Academic Article
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CD34-positive acute promyelocytic leukemia is associated with leukocytosis, microgranular/hypogranular morphology, expression of CD2 and bcr3 isoform Academic Article
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Canadian ROS proto-oncogene 1 study (CROS) for multi-institutional implementation of ROS1 testing in non-small cell lung cancer Academic Article
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Cardiovascular Events After Exposure to Nilotinib in Chronic Myeloid Leukemia: Long-term Follow-up Academic Article
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Cardiovascular events in chronic myeloid leukemia clinical trials. Is it time to reassess and report the events according to cardiology guidelines? Academic Article
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Conformational Studies on Calcium Binding BytBoc-Leu-Pro-Tyr-Ala-NHCH3, a Tyrosine Kinase Substrate, in a Nonpolar Solvent Academic Article
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Crizotinib Inhibition of ROS1-Positive Tumours in Advanced Non-Small-Cell Lung Cancer: A Canadian Perspective Academic Article
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Differences in Functional Consequences and Signal Transduction Induced by IL-3, IL-5, and Nerve Growth Factor in Human Basophils Academic Article
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Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis Academic Article
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Endothelial cell tumors develop in transgenic mice carrying polyoma virus middle T oncogene Academic Article
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Estrogen induced changes in uterine brain-derived neurotrophic factor and its receptors Academic Article
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Excitation-contraction coupling in pulmonary vascular smooth muscle involves tyrosine kinase and Rho kinase Academic Article
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Exon-skipping in BCR/ABL is induced by ABL exon 2 Academic Article
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Identification of MEK- and phosphoinositide 3-kinase-dependent signalling as essential events during Chlamydia pneumoniae invasion of HEp2 cells Academic Article
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Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes. Academic Article
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Identification of a novel Wee1 isoform Academic Article
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Mirk/Dyrk1b Mediates Cell Survival in Rhabdomyosarcomas Academic Article
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Molecular cloning and characterization of PEA3, a new member of the Ets oncogene family that is differentially expressed in mouse embryonic cells. Academic Article
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Myb and Ets related transcription factors are required for activity of the human lck type I promoter. Academic Article
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NMDA and dopamine D2L receptor interaction in human neuroblastoma SH-SY5Y cells involves tyrosine kinase and phosphatase Academic Article
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Nintedanib plus Sildenafil in Patients with Idiopathic Pulmonary Fibrosis Academic Article
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Nuclear Targeting of Methyl-Recycling Enzymes in Arabidopsis thaliana Is Mediated by Specific Protein Interactions Academic Article
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Nucleotide Selectivity of Antibiotic Kinases Academic Article
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Osimertinib in UntreatedEGFR-Mutated Advanced Non–Small-Cell Lung Cancer Academic Article
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Perivascular adipose tissue promotes vasoconstriction: the role of superoxide anion Academic Article
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Phase I and Pharmacokinetic Study of Daily Oral AZD2171, an Inhibitor of Vascular Endothelial Growth Factor Tyrosine Kinases, in Combination With Carboplatin and Paclitaxel in Patients With Advanced Non–Small-Cell Lung Cancer: The National Cancer Institute of Canada Clinical Trials Group Academic Article
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Phase II Study of Lapatinib in Recurrent or Metastatic Epidermal Growth Factor Receptor and/or erbB2 Expressing Adenoid Cystic Carcinoma and Non–Adenoid Cystic Carcinoma Malignant Tumors of the Salivary Glands Academic Article
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PhenCode: connecting ENCODE data with mutations and phenotype Academic Article
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Phosphorylation of PITSLRE p110 Isoforms Accompanies Their Processing by Caspases during Fas-mediated Cell Death Academic Article
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Prenatal sonographic diagnosis of hypochondroplasia in a high‐risk fetus Academic Article
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Regulation of plasminogen activator inhibitor-1 secretion by growth factors in smooth muscle cells Academic Article
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Regulation of plasminogen activator inhibitor-1 secretion by urokinase and tissue plasminogen activator in rat epithelioid-type smooth muscle cells Academic Article
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Requirement of an ETS-binding element for transcription of the human lck type I promoter. Academic Article
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Responsiveness of canine bronchial vasculature to excitatory stimuli and to cooling Academic Article
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Reversion of middle T antigen-transformed Rat-2 cells by Krev-1: implications for the role of p21c-ras in polyomavirus-mediated transformation. Academic Article
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Role for IL-4 in macromolecular transport across human intestinal epithelium Academic Article
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Role of Tyrosine Phosphorylation in U46619-induced Vasoconstriction of Pulmonary Vasculature and Its Modulation by Genistein, Daidzein, and Equol Academic Article
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Role of the actin cytoskeleton in insulin action Academic Article
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Signals for local and systemic responses of plants to pathogen attack Academic Article
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Simultaneous overexpression of avian pp60c-src and polyomavirus middle T antigen in mammalian cells Academic Article
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Specific CD45 Isoforms Regulate T Cell Ontogeny and Are Functionally Distinct in Modifying Immune Activation Academic Article
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Stability and peptide binding specificity of Btk SH2 domain: Molecular basis for X-linked agammaglobulinemia Academic Article
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Sustained activation of the extracellular signal-regulated kinase pathway protects cells from photofrin-mediated photodynamic therapy. Academic Article
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Synthetic beta-turn peptides as substrates for a tyrosine protein kinase. Academic Article
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Targeted disruption of β1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction Academic Article
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The activity of the Ets transcription factor PEA3 is regulated by two distinct MAPK cascades. Academic Article
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The amino terminus of polyomavirus middle T antigen is required for transformation Academic Article
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The lnterleukin-5/Receptor Interaction Activates Lyn and Jak2 Tyrosine Kinases and Propagates Signals via the Ras-Raf-1-MAP Kinase and the Jak-STAT Pathways in Eosinophils Conference Paper
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The rapidly evolving landscape of novel targeted therapies in advanced non-small cell lung cancer Academic Article
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The risk of atrial fibrillation with ibrutinib use: a systematic review and meta-analysis Academic Article
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Therapeutic Potential of Spleen Tyrosine Kinase Inhibition for Treating High-Risk Precursor B Cell Acute Lymphoblastic Leukemia Academic Article
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Thymic CD45 tyrosine phosphatase regulates apoptosis and MHC-restricted negative selection. Academic Article
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Tyrosine kinase inhibitors and tumor lysis syndrome in hematologic malignancies: A systemic review Academic Article
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Tyrosine phosphorylation and cadherin/catenin function Academic Article
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Vasoconstrictor actions of isoprostanes via
tyrosine kinase and Rho kinase in human and canine pulmonary vascular smooth muscles Academic Article
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XXIII International Association for Comparative Research on Leukemia and Related Diseases Symposium: from Molecular Pathogenesis to Targeted Therapy in Leukemia and Solid Tumors Conference Paper
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β2 integrin–derived signals induce cell survival and proliferation of AML blasts by activating a Syk/STAT signaling axis Academic Article