Protein-Tyrosine Kinases Concept

subject area of

• 1,25-Dihydroxyvitamin D3Primes Acute Promyelocytic Cells for TPA-Induced Monocytic Differentiation through Both PKC and Tyrosine Phosphorylation Cascades  Journal Articles
• A pharmacodynamic study of the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in metastatic colorectal cancer patients.  Journal Articles
• Achondroplasia–hypochondroplasia complex in a newborn infant  Journal Articles
• Adenosine downregulates DPPIV on HT-29 colon cancer cells by stimulating protein tyrosine phosphatase(s) and reducing ERK1/2 activity via a novel pathway  Journal Articles
• Assembly of Bcl-2 into microsomal and outer mitochondrial membranes  Journal Articles
• Brain-derived neurotrophic factor and TrkB expression in the “oldest-old,” the 90+ Study: correlation with cognitive status and levels of soluble amyloid-beta  Journal Articles
• CANTRK  Journal Articles
• CD34‐positive acute promyelocytic leukemia is associated with leukocytosis, microgranular/hypogranular morphology, expression of CD2 and bcr3 isoform  Journal Articles
• Canadian ROS proto-oncogene 1 study (CROS) for multi-institutional implementation of ROS1 testing in non-small cell lung cancer  Journal Articles
• Cardiovascular Events After Exposure to Nilotinib in Chronic Myeloid Leukemia: Long-term Follow-up  Journal Articles
• Cardiovascular events in chronic myeloid leukemia clinical trials. Is it time to reassess and report the events according to cardiology guidelines?  Journal Articles
• Clinical and Molecular Studies of the Effect of Imatinib on Advanced Aggressive Fibromatosis (desmoid tumor)  Journal Articles
• Conformational Studies on Calcium Binding BytBoc-Leu-Pro-Tyr-Ala-NHCH₃, a Tyrosine Kinase Substrate, in a Nonpolar Solvent  Journal Articles
• Crizotinib Inhibition of ROS1-Positive Tumours in Advanced Non-Small-Cell Lung Cancer: A Canadian Perspective  Journal Articles
• Differences in Functional Consequences and Signal Transduction Induced by IL-3, IL-5, and Nerve Growth Factor in Human Basophils  Journal Articles
• Economic Analysis: Randomized Placebo-Controlled Clinical Trial of Erlotinib in Advanced Non-Small Cell Lung Cancer  Journal Articles
• Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis  Journal Articles
• Endothelial cell tumors develop in transgenic mice carrying polyoma virus middle T oncogene  Journal Articles
• Estrogen induced changes in uterine brain-derived neurotrophic factor and its receptors  Journal Articles
• Excitation-contraction coupling in pulmonary vascular smooth muscle involves tyrosine kinase and Rho kinase  Journal Articles
• Exon-skipping in BCR/ABL is induced by ABL exon 2  Journal Articles
• Glucose transporter expression in L6 muscle cells: Regulation through insulin- and stress-activated pathways  Journal Articles
• Identification of MEK- and phosphoinositide 3-kinase-dependent signalling as essential events during Chlamydia pneumoniae invasion of HEp2 cells  Journal Articles
• Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes.  Journal Articles
• Identification of a novel Wee1 isoform  Journal Articles
• Lorlatinib Effectiveness and Quality-of-Life in Patients with ALK-Positive NSCLC Who Had Failed Second-Generation ALK Inhibitors: Canadian Real-World Experience  Journal Articles
• Mirk/Dyrk1b Mediates Cell Survival in Rhabdomyosarcomas  Journal Articles
• Molecular cloning and characterization of PEA3, a new member of the Ets oncogene family that is differentially expressed in mouse embryonic cells.  Journal Articles
• Multicenter, Randomized Phase II Trial of Oral CI-1033 for Previously Treated Advanced Ovarian Cancer  Journal Articles
• NMDA and dopamine D2L receptor interaction in human neuroblastoma SH-SY5Y cells involves tyrosine kinase and phosphatase  Journal Articles
• Nintedanib plus Sildenafil in Patients with Idiopathic Pulmonary Fibrosis  Journal Articles
• Nuclear Targeting of Methyl-Recycling Enzymes in Arabidopsis thaliana Is Mediated by Specific Protein Interactions  Journal Articles
• Nucleotide Selectivity of Antibiotic Kinases  Journal Articles
• Osimertinib in UntreatedEGFR-Mutated Advanced Non–Small-Cell Lung Cancer  Journal Articles
• Perivascular adipose tissue promotes vasoconstriction: the role of superoxide anion  Journal Articles
• Phase I and Pharmacokinetic Study of Daily Oral AZD2171, an Inhibitor of Vascular Endothelial Growth Factor Tyrosine Kinases, in Combination With Carboplatin and Paclitaxel in Patients With Advanced Non–Small-Cell Lung Cancer: The National Cancer Institute of Canada Clinical Trials Group  Journal Articles
• Phase II Study of Lapatinib in Recurrent or Metastatic Epidermal Growth Factor Receptor and/or erbB2 Expressing Adenoid Cystic Carcinoma and Non–Adenoid Cystic Carcinoma Malignant Tumors of the Salivary Glands  Journal Articles
• PhenCode: connecting ENCODE data with mutations and phenotype  Journal Articles
• Phosphorylation of PITSLRE p110 Isoforms Accompanies Their Processing by Caspases during Fas-mediated Cell Death  Journal Articles
• Prenatal sonographic diagnosis of hypochondroplasia in a high‐risk fetus  Journal Articles
• Regulation of plasminogen activator inhibitor-1 secretion by growth factors in smooth muscle cells  Journal Articles
• Regulation of plasminogen activator inhibitor‐1 secretion by urokinase and tissue plasminogen activator in rat epithelioid‐type smooth muscle cells  Journal Articles
• Responsiveness of canine bronchial vasculature to excitatory stimuli and to cooling  Journal Articles
• Reversion of middle T antigen-transformed Rat-2 cells by Krev-1: implications for the role of p21c-ras in polyomavirus-mediated transformation.  Journal Articles
• Role for IL-4 in macromolecular transport across human intestinal epithelium  Journal Articles
• Role of Tyrosine Phosphorylation in U46619-induced Vasoconstriction of Pulmonary Vasculature and Its Modulation by Genistein, Daidzein, and Equol  Journal Articles
• Role of the actin cytoskeleton in insulin action  Journal Articles
• Signals for local and systemic responses of plants to pathogen attack  Journal Articles
• Simultaneous overexpression of avian pp60c-src and polyomavirus middle T antigen in mammalian cells  Journal Articles
• Site-directed point mutation in the src gene oF rous sarcoma virus results in an inactive src gene product  Journal Articles
• Specific CD45 Isoforms Regulate T Cell Ontogeny and Are Functionally Distinct in Modifying Immune Activation  Journal Articles
• Stability and peptide binding specificity of Btk SH2 domain: Molecular basis for X‐linked agammaglobulinemia  Journal Articles
• Sustained activation of the extracellular signal-regulated kinase pathway protects cells from photofrin-mediated photodynamic therapy.  Journal Articles
• Synthetic beta-turn peptides as substrates for a tyrosine protein kinase.  Journal Articles
• Targeted disruption of β1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction  Journal Articles
• The activity of the Ets transcription factor PEA3 is regulated by two distinct MAPK cascades.  Journal Articles
• The amino terminus of polyomavirus middle T antigen is required for transformation  Journal Articles
• The rapidly evolving landscape of novel targeted therapies in advanced non-small cell lung cancer  Journal Articles
• The risk of atrial fibrillation with ibrutinib use: a systematic review and meta-analysis  Journal Articles
• Therapeutic Potential of Spleen Tyrosine Kinase Inhibition for Treating High-Risk Precursor B Cell Acute Lymphoblastic Leukemia  Journal Articles
• Thymic CD45 tyrosine phosphatase regulates apoptosis and MHC-restricted negative selection.  Journal Articles
• Tyrosine kinase inhibitors and tumor lysis syndrome in hematologic malignancies: A systemic review  Journal Articles
• Tyrosine phosphorylation and cadherin/catenin function  Journal Articles
• Vasoconstrictor actions of isoprostanes via tyrosine kinase and Rho kinase in human and canine pulmonary vascular smooth muscles  Journal Articles
• XXIII International Association for Comparative Research on Leukemia and Related Diseases Symposium: from Molecular Pathogenesis to Targeted Therapy in Leukemia and Solid Tumors  Conferences
• β2 integrin–derived signals induce cell survival and proliferation of AML blasts by activating a Syk/STAT signaling axis  Journal Articles