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The rapidly evolving landscape of novel targeted...
Journal article

The rapidly evolving landscape of novel targeted therapies in advanced non-small cell lung cancer

Abstract

Lung cancer is a highly heterogeneous disease often driven by well-characterized driver mutations. Although the best studied are common alterations in the epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) oncogenes, rapid advances in molecular characterization has led to the development of novel therapeutics that inhibit additional oncogenic alterations in advanced NSCLC. The literature search identified 62 eligible …

Authors

Melosky B; Wheatley-Price P; Juergens RA; Sacher A; Leighl NB; Tsao M-S; Cheema P; Snow S; Liu G; Card PB

Journal

Lung Cancer, Vol. 160, , pp. 136–151

Publisher

Elsevier

Publication Date

October 2021

DOI

10.1016/j.lungcan.2021.06.002

ISSN

0169-5002